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Posted By: Sra1 Member Level: Diamond Posted Date: 27 May 2008
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2007 Jawaharlal Nehru Technological University B.Tech Biotechnology BIO-INFORMATICS (Supplimentary Examinations, Aug/Sep 2007) Question paper
Set No 1
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Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
1. What is Bioinformatics? Describe its scope in modern biology? [16]
2. Write short notes on:
(a) Gapped BLAST
(b) PSI-BLAST
(c) BLAST (2) [16]
3. What is multiple sequence alignment? Describe the applications of multiple sequence alignments? [16]
4. Describe the following:
(a) Structural classifications of proteins
(b) The CATH (Class, Architecture, Topology, Homology) databases [16]
5. Explain Database searching with Smith-waterman Dynamic programming method? [16]
6. Describe about Phylogenetic tree construction by using UPGMA method? [16]
7. Define Genome? Outline the structure and composition of prokaryotic and Eukaryotic genomes? [16]
8. Write short notes on:
(a) GRAIL II
(b) ORF [16]
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