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Posted By: srinivas Member Level: Gold Posted Date: 30 May 2008
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2008 Andhra Pradesh State Jawaharlal Nehru Technological University Biotechnology III B.Tech II Semester Supplimentary Examinations, Apr/May 2008 PROTEIN ENGINEERING Question paper
Code No: RR322306 Set No. 2
III B.Tech II Semester Supplimentary Examinations, Apr/May 2008
PROTEIN ENGINEERING
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
1. (a) Describe the assembly of a- helix, with examples.
(b) Describe the geometry of the peptide bond in details. [8+8]
2. Describe the role of hydrophobic forces in tertiary structure. [16]
3. Justify the statement - “Information of final structure of protein lies in its primary
structure”. [16]
4. Describe the zinc finger and their function. [16]
5. Write a note on interactions of proteins in membrane with a neat sketch showing
various classes of proteins associated with the lipid bi-layer? [16]
6. Write in detail about basic structure and function of Immunoglobulin? [16]
7. Describe the advantages and disadvantages of oligonucleotide - directed mutagenesis
using PCR. [16]
8. Explain the importance of protein designing in the field of Drug designing. [16]
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