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Posted By: Sra1       Member Level: Diamond       Posted Date: 02 Jun 2008

2008 Jawaharlal Nehru Technological University Biotechnology PROTEIN ENGINEERING (III B.Tech II Semester Supplimentary Examinations, Apr/May 2008) Question paper



Course: B.Tech Biotechnology   University: Jawaharlal Nehru Technological University




Set No 2
------------


III B.Tech II Semester Supplimentary Examinations, Apr/May 2008
PROTEIN ENGINEERING
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
* * * * *


1. (a) Describe the assembly of a- helix, with examples.
(b) Describe the geometry of the peptide bond in details. [8+8]

2. Describe the role of hydrophobic forces in tertiary structure. [16]

3. Justify the statement - “Information of final structure of protein lies in its primary structure”. [16]

4. Describe the zinc finger and their function. [16]

5. Write a note on interactions of proteins in membrane with a neat sketch showing various classes of proteins associated with the lipid bi-layer? [16]

6. Write in detail about basic structure and function of Immunoglobulin? [16]

7. Describe the advantages and disadvantages of oligonucleotide - directed mutagenesis using PCR. [16]

8. Explain the importance of protein designing in the field of Drug designing. [16]





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