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Posted By: Shanthi M Member Level: Diamond Posted Date: 03 Jun 2008
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2007 Tamil Nadu State Annamalai University M.Sc BioTechnology Molecular Modeling and Drug Design Question paper
M.Sc DEGREE EXAMINATION, 2007
(BIO-INFORMATICS)
(FOURTH SEMESTER)
(PAPER-XX)
420. MOLECULAR MODELING AND DRUG DESIGN
Dec] [Time : 3 Hours
Maximum : 100 Marks
Answer any FIVE Questions
All questions carry equal marks
1. Discuss the physiochemical principles of drug action.
2. Write an account of lead discovery and optimization.
3. List out the current regulatory affairs on racemic drugs.
4. What are receptors? Discuss with suitable examples, the importance of receptors in drug design.
5. Write a detailed account on structure aided drug design.
6. Briefly describe various in Silico methods used to model three dimensional structures.
7. Explain the different approaches adopted in drug design.
8. Discuss in detail about ADME and molecular descriptors
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