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Posted By: Sanjana Member Level: Gold Posted Date: 11 Jun 2008
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2007 Cell Biology and Genetics Degree Examination September Question paper
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Cell Biology and Genetics Degree Examination September SCHOOL OF BIOLOGY
UNIVERSITY OF ST. ANDREWS
CELL BIOLOGY AND GENETICS
MODULE BL1001
2005-6
DEGREE EXAMINATION
September 2006
Time available: 2 hours
PRINT your name in BLOCK CAPITALS here, and at the
top of each page where requested:
SURNAME: ......................................................................................................
GIVEN NAMES (in full): ................................................................................
MATRICULATION NO: ................................................................................
This examination paper comprises 10 questions, of which
you must answer 8.
All questions carry equal value.
This examination book will be taken apart before marking, so WRITE YOUR ANSWERS ONLY ON THE PAGE ON WHICH THE QUESTION APPEARS.
Cell Biology & Genetics Degree Examination September Page 2
MATRICULATION NO.:
...............................................................................................................................
1. What is the evidence for the fluid mosaic model of the plasma membrane?
EXAMINER: please mark out of 10, and put mark here ...............
Cell Biology & Genetics Degree Examination September Page 3
MATRICULATION NO.:
...............................................................................................................................
2. With the aid of a diagram, explain the main interactions that occur during the contraction of striated muscle.
EXAMINER: please mark out of 10, and put mark here ...............
Cell Biology & Genetics Degree Examination September Page 4
MATRICULATION NO.:
...............................................................................................................................
3. A testcross produces the following numbers of offspring which show the wildtype (+) or mutant phenotypes A, B and C. Construct a genetic map, showing all your working.
A B C 50
+ + + 50
A B + 350
+ + C 350
A + C 85
+ B + 85
+ B C 15
A + + 15
1000 TOTAL PROGENY
The parental classes are _______________ and ________________. (2 marks)
The map is: (8 marks)
EXAMINER: please mark out of 10, and put mark here ...............
Cell Biology & Genetics Degree Examination September Page 5
MATRICULATION NO.:
...............................................................................................................................
4.
(i) Haemophilia is an X-linked recessive disorder. A normal woman whose father was haemophilic marries a normal man. They have a haemophilic son. The man claims his wife has been unfaithful. If you were a judge, how would you rule and why? (3 marks)
(ii) In humans, having attached earlobes is recessive to having free earlobes. A woman and her husband both have free earlobes, although each happens to have a father with attached earlobes. Is it possible for this woman and man to have a child with attached earlobes? Please explain by indicating the genotypes of the parents and child. (3 marks)
(iii) Two short-tailed cats are mated. In the progeny, two have no tails, six have short tails and three have long tails. Explain the cross with the aid of a diagram. (4 marks)
EXAMINER: please mark out of 10, and put mark here ...............
Cell Biology & Genetics Degree Examination September Page 6
MATRICULATION NO.:
...............................................................................................................................
5.
(a) How does the bicoid gene control early Drosophila development?
OR
(b) Outline the main features of cleavage and gastrulation.
EXAMINER: please mark out of 10, and put mark here ...............
Cell Biology & Genetics Degree Examination September Page 7
MATRICULATION NO.:
...............................................................................................................................
6. Write notes on FOUR of the following:
The effect of ionising radiation on chromosomes, penetrance, heterozygote advantage, the insect hormone ecdysone, somatic mutation, the cell cycle.
(i)
(ii)
(iii)
(iv)
EXAMINER: please mark out of 10, and put mark here ...............
Cell Biology & Genetics Degree Examination September Page 8
MATRICULATION NO.:
...............................................................................................................................
7.
EITHER
Gregor Mendel has been proposed for a new award, a posthumous Nobel Laureate. Write him a reference.
OR
Write an essay on genetic linkage.
EXAMINER: please mark out of 10, and put mark here ...............
Cell Biology & Genetics Degree Examination September Page 9
MATRICULATION NO.:
...............................................................................................................................
8. Use a diagram to explain what is meant by the 'lytic' and 'lysogenic' life-cycle modes of bacteriophage.
EXAMINER: please mark out of 10, and put mark here ...............
Cell Biology & Genetics Degree Examination September Page 10
MATRICULATION NO.:
...............................................................................................................................
9. With the aid of a labelled diagram, explain the functional role and importance of a chloroplast's antenna complexes.
EXAMINER: please mark out of 10, and put mark here ...............
Cell Biology & Genetics Degree Examination September Page 11
MATRICULATION NO.:
...............................................................................................................................
10. With the aid of diagrams, explain in general terms how the active site of an enzyme functions.
EXAMINER: please mark out of 10, and put mark here ...............
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