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Posted By: Sanjana Member Level: Gold Posted Date: 11 Jun 2008
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2005 Cell Biology and Genetics Degree Examination Question paper
Cell Biology and Genetics Degree Examination SCHOOL OF BIOLOGY UNIVERSITY OF ST. ANDREWS CELL BIOLOGY AND GENETICS MODULE BL1001 2004-5 DEGREE EXAMINATION January 2005 Time available: 2 hours PRINT your name in BLOCK CAPITALS here, and at the top of each page where requested: SURNAME: ...................................................................................................... GIVEN NAMES (in full): ................................................................................ This examination paper comprises 9 questions, of which you must answer 8. All questions carry equal value. This examination book will be taken apart before marking, so WRITE YOUR ANSWERS ONLY ON THE PAGE ON WHICH THE QUESTION APPEARS. Cell Biology & Genetics Degree Examination January Page 2 MATRICULATION NO.: ............................................................................................................................... 1. Outline the main mechanisms by which material is transported across the cell membrane. EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination January Page 3 MATRICULATION NO.: ............................................................................................................................... 2. What are proteins, and what are their main functions inside cells? EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination January Page 4 MATRICULATION NO.: ............................................................................................................................... 3. A testcross produces the following numbers of offspring which show the wild type (+) or mutant phenotypes, A, B or C. Construct a genetic map, showing all your working. A B C 150 + + + 150 A B + 270 + + C 270 A + + 10 + B C 10 A + C 70 + B + 70 Total 1000 The parental classes are ____________ and ____________ (2 marks) The map is: (8 marks) EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination January Page 5 MATRICULATION NO.: ............................................................................................................................... 4. Write notes on FOUR of the following: gastrulation, Huntingdon's disease, testcross, epistasis, ribosomal RNA, the synaptonemal complex. (1) A note on: (2) A note on: (3) A note on: (4) A note on: EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination January Page 6 MATRICULATION NO.: ............................................................................................................................... 5. (a) Two short-tailed cats are mated. In the progeny, two have no tails, six have short tails, and three have long tails. Explain these results by diagramming the cross. What mode of inheritance do we see? (4 marks) (b) EITHER: What clues to the structure of DNA were available to Watson and Crick? OR: Write a note on microscopy in the 18th Century. (6 marks) EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination January Page 7 MATRICULATION NO.: ............................................................................................................................... 6. (a) The red alga Polyides rotundus stores its genetic information in doublestranded DNA. When DNA was extracted from P. rotundus cells and analysed, 32% of the bases were found to be guanine residues. From this information, can you determine what percentage of the bases in this DNA were thymine residues? If not, why not? ANSWER: (2 marks) (b) In the pedigrees below, determine whether the trait is more likely to be due to a dominant or a recessive allele, and whether it is autosomal or X-linked. ANSWER A ………………………………………………… (2 marks) ANSWER B ………………………………………………… (2 marks) In pedigree B above, what is the chance that the couple III-1 and III-2 will have an affected child? Answer………………… (2 marks) In pedigree B above, what is the chance that couple IV-2 and IV-3 will have an affected child? ANSWER: …………………………….. (2 marks) EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination January Page 8 MATRICULATION NO.: ............................................................................................................................... 7. Using diagrams, explain how prokaryotes recycle carbon and nitrogen within the ecosystem. EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination January Page 9 MATRICULATION NO.: ............................................................................................................................... 8. With the aid of a diagram, explain the differences between cyclic photophosphorylation and non-cyclic photophosphorylation during photosynthesis. EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination January Page 10 MATRICULATION NO.: ............................................................................................................................... 9. With the aid of diagrams, explain the importance of weak bonds at the active site of an enzyme. EXAMINER: please mark out of 10, and put mark here ...............
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