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Posted By: Sanjana Member Level: Gold Posted Date: 11 Jun 2008
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2005 Cell Biology and Genetics Degree Examination Question paper
Cell Biology and Genetics Degree Examination SCHOOL OF BIOLOGY UNIVERSITY OF ST. ANDREWS CELL BIOLOGY AND GENETICS MODULE BL1001 2004-5 DEGREE EXAMINATION August 2005 Time available: 2 hours PRINT your name in BLOCK CAPITALS here, and at the top of each page where requested: SURNAME: ...................................................................................................... GIVEN NAMES (in full): ................................................................................ This examination paper comprises 9 questions, of which you must answer 8. All questions carry equal value. This examination book will be taken apart before marking, so WRITE YOUR ANSWERS ONLY ON THE PAGE ON WHICH THE QUESTION APPEARS. Cell Biology & Genetics Degree Examination August Page 2 MATRICULATION NO.: ............................................................................................................................... 1. Describe the key structural features of the cell (plasma) membrane. EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination August Page 3 MATRICULATION NO.: ............................................................................................................................... 2. What are vesicles? Give examples of some of their functions inside cells. EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination August Page 4 MATRICULATION NO.: ............................................................................................................................... 3. A testcross produces the following numbers of offspring which show the wildtype (+) or mutant phenotypes A, B and C. Construct a genetic map, showing all your working. A B C 140 A B + 300 + + + 140 + + C 300 A + + 15 A + C 45 + B C 15 + B + 45 1000 The parental classes are _______________ and ________________. (2 marks) The map is: (8 marks) EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination August Page 5 MATRICULATION NO.: ............................................................................................................................... 4. Write notes on FOUR of the following: phenotype, sex determination in alligators, the DNA replication fork, polytene chromosomes, introns, balanced polymorphism. (1) A note on: (2) A note on: (3) A note on: (4) A note on: EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination August Page 6 MATRICULATION NO.: ............................................................................................................................... 5. Write a brief essay on the early development of Drosophila embryos. OR How do we know that the genetic code is read in triplets? EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination August Page 7 MATRICULATION NO.: ............................................................................................................................... 6. (a) The M, N and MN blood groups are determined by two alleles, LM and LN. The ABO blood groups are determined by three alleles. The Rh+ (rhesus positive) blood group is caused by a dominant allele R of a different gene. In a court case concerning a paternity dispute, each of the two men claimed three children to be his own. The blood groups of the men, the children and their mother were: HUSBAND 0 M Rh+ WIFE'S LOVER AB MN Rh+ WIFE A N Rh+ CHILD 1 0 MN Rh+ CHILD 2 A N Rh+ CHILD 3 A MN Rh+ For each of the children, give the paternity (or state that it cannot be established from this evidence) and give your reasons. The parent of child 1 is: …………………………………. (2 marks) REASON: The parent of child 2 is: …………………………………. (2 marks) REASON: The parent of child 3 is: …………………………………. (2 marks) REASON: (b) Mitosis and meiosis always differ in regard to the presence of one of the following: chromatids, homologs, bivalents, centromeres, spindles. Which one? Answer: ………………………………………………… (2 marks) (c) In humans, differences in the ability to taste phenylthiourea are due to a pair of recessive alleles. Inability to taste is recessive to ability to taste. A child who is a nontaster is born to a couple who can both taste the substance. What is the probability that their next child will be a taster? Answer: ………………………………………………… (2 marks) EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination August Page 8 MATRICULATION NO.: ............................................................................................................................... 7. Using examples, describe what is meant by the 'pathogenicity' of some prokaryotes. EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination August Page 9 MATRICULATION NO.: ............................................................................................................................... 8. With the aid of a diagram, explain the important roles of protons and electrons that are associated with the inner mitochondrial membrane and its cristae during the generation of ATP. EXAMINER: please mark out of 10, and put mark here ............... Cell Biology & Genetics Degree Examination August Page 10 MATRICULATION NO.: ............................................................................................................................... 9. With the aid of diagrams, explain the importance of light-harvesting pigments during photosynthesis. EXAMINER: please mark out of 10, and put mark here ...............
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