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Posted By: India Member Level: Diamond Posted Date: 22 Jan 2008
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2007 Rajiv Gandhi University of Health Sciences M.B.B.S February 2007-PHARMACOLOGY - PAPER - I (Revised Scheme 2)-PHASE - II Degree Examination Question paper
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Rajiv Gandhi University of Health Sciences
M.B.B.S. PHASE - II Degree Examination - February 2007
Time: 3 Hrs. [Max. Marks: 100]
PHARMACOLOGY - PAPER I (Revised Scheme 2)
QP Code: 1085
By Dr.Bhargava, JJMMC, Davangere
&
Dr.Nandish, BMC
Q Paper Courtesy: Dr. Singi Yatiraj
LONG ESSAY 2 X 10 = 20 Marks
1. Classify Antihypertensive drugs with examples for each group. Explain mechanism of
action, therapeutic uses and adverse effects of Angiotensin Converting enzyme (ACE)
inhibitors.
2. Classify Anticholinergic drugs with examples for each group. Describe pharmacological
actions, therapeutic uses and adverse effects of Atropine.
SHORT ESSAY 10 X 5 = 50 Marks
3. Explain protein binding of drugs with suitable examples. Give its clinical importance.
4. Explain basis for use of Nitroglycerine in Angina pectoris. Enumerate routes of
administration and unwanted effects.
5. Lignocaine â mechanism of action, indications for use and various routes of
administration and two side effects.
6. Carbamazepine â indicat ions for use and side effects.
7. Drug - Drug antagonism â Define, mention the types and mechanisms with
examples.
8. What are Fibrinolytic agents? Give examples â mechanisms and their uses.
9. Mention Beta2 agonists and write their therapeutic uses and side effects.
10. Mention plasminogen activators with their therapeutic indications and side effects.
11. What are atypical antipsychotics? Mention examples of advantages over the older ones.
12. Mention organophosphorous compounds. How do you treat organophosphorous
poisoning?
SHORT ANSWERS 10 X 3 = 30 Marks
13. State the basis for the use of Pilocarpine in glaucoma. Mention two adverse
effects.
14. State reasons â Chlorpromazine is an antiemetic but is not useful in motion
sickness.
15. State reasons â Dopamine is preferred to noradrenaline in circulatory failure.
16. Mention advantages and disadvantages of sublingual route of drug
administration.
17. What is neuroleptanalgesia? What are the drugs used for it?
18. What is Atracurium? How is it eliminated from the body? Write indications for its
use.
19. Methadone â explain the basis for its use in heroin dependence.
20. Malignant Hyperthermia. Mention the drugs causing this condition and outline the
treatment.
21. Mention two COMT (Catechol â O â Methyl transferase) inhibitors in the
treatment of Alzheimerâs disease. Mention two adverse effects.
22. Orphan drugs â define & give examples.
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