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Posted Date: 20 Nov 2012      Posted By:: Sandeep    Member Level: Silver    Points: 5 (Rs. 5)

2012 University of Pune B.Pharm Second Year B. Pharmacy Examination , April 2012 Physical Pharmacy (2008 Pattern) University Question paper



Course: B.Pharm   University/board: University of Pune

Are you looking for the second year B. Pharmacy question paper of University of Pune. Here is the original question paper of second year B.Pharmacy Examination conducted in April 2012 for the subject of Physical Pharmacy.



Second Year B.Pharmacy Examination, 2012
2.1: PHYSICAL PHARMACY
(2008 Pattern)

Time: 3 Hours
Max. Marks: 80

Instructions: 1) Answer to the two sections should be written in separate books.
2) Neat diagrams must be drawn wherever necessary.
3) Black figures to the right indicate full marks.
4) All questions are compulsory
.................................................................................
SECTION - I

Q1. Attempt any one: [10]

Discuss solubility of solids in liquids and factors affecting it.

OR

Discuss phase rule. Explain two component system in detail.

Q2. Answer any five (3 marks each): [15]
i) Explain gold number along with examples.
ii) Explain Schulz Hardy rule and Hoffemeister series.
iii) Define and differentiate triple point and freezing points of water.
iv) Differentiate between ideal and real solutions.
v) Discuss solute solvent interaction.
vi) Define crystallization and explain factors affecting crystallization.
Vii) Explain Lindes method of liquifaction of gases.

Q3. Write short notes on any three (5 marks each: [15]
i) Methods of Crystal analysis.
ii) Thermodynamic principles in solubilization.
iii) Arrhenius theory of electrolytes.
iv) Partition coefficient.
v) Explain the electrical properties of colloids.

................................................................................

SECTION II

Q4. Attempt any one: [10]

Define adsorption isotherm. Draw various types of adsorption isotherm and explain their behavior.

OR

Compare first and second order reactions with respect to the rates and explain the mechanism for their behavior.

Q5. Answer any five (3 marks each): [15]
i) Write the equation for the spreading coefficient. Suggest two methods to improve the spreading of a medicament.
ii) Define angle of repose. What are its uses in the pharmaceutical field ?
iii) Define thixotropy. Describe the role of thixotropy in formulations.
iv) Differentiate between dissolution and diffusion.
v) What are the applications of Coulter-counter apparatus ?
vi) Draw the flow curve for antithixotropic flow and explain its mechanism.
vii) Write applications of chemical kinetics.

Q6. Write short notes on any three (5 marks each) [15]
i) Gibbs equation and soluble monolayer
ii)Dissolution test apparatus (USP)
iii) Ficks law of diffusion
iv) Factors affecting flow of powders
v) Du Nouy method for surface tension determination.
................................................................................





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