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2016 Manonmaniam Sundaranar University General B.Sc Microbiology BSc (CBCS) degree examination / Fundamentals of immunology /Manonmaniam sudaranar university Question paper



Course: B.Sc Microbiology   University/board: Manonmaniam Sundaranar University

are you a microbiology student.are you searching for fundamentals of microbiology previous year question.this is original question from manonmaniam sundaranar university. if you want this question for preparation please download from here.Use thi question properly for preparation and score well.



CODE: 30958 SUB CODE: GMMI41
BSC (CBCS) DEGREE EXAMINATION, APRIL 2016
FOURTH SEMESTER
MICROBIOLOGY – MAIN
FUNDAMENTALS OF IMMUNOLOGY
CHOOSE THE CORRECT ANSWER:
1. Immunological memory is a feature exhibited by
(a) Cell – mediated immunity
(b) Adaptive immunity
(c) Humoral immunity
(d) Innate immunity
2. __________ the presence of ABO incompatibility between mother and fetus increase the likelihood of developing symptoms of Rh incompatibility.
(a) Agglutination
(b) Flocculation
(c) Both (a) and (b)
(d) None
3. The light and heavy chains of an IgG held to each other by
(a) Covalent bond
(b) Non covalent bond
(c) Both
(d) Neither
4. Tissue macrophages are mature
(a) B cells
(b) T cells
(c) NK cells
(d) Monocytes
5. Antigen presenting cells
(a) Express both MHC class I and class II molecules
(b) Only express Fe receptors
(c) Express CD4 molecules on their surface
(d) Display the invariant chain of the MHC class II molecule on the plasma membrane
6. Peptide vaccines are desirable because
(a) They don't expose patients to active pathogens
(b) They are easier to manufacture than live pathogen
(c) They always evoke a cell mediated immunity
(d) They can be readily made to produce a cross reactive immunity
7. Antibody affinity is not determined by the amino acid sequence in
(a) The constant region of the immunoglobulin molecule.
(b) The variable region of the immunoglobulin molecule.
(c) The Fc of the immunoglobulin molecule.
(d) (a), (b), and (c)
8. IgE
(a) Is produced by mast cells
(b) Is produced by B cells
(c) Is produced by T cells
(d) Binds to mast cells
9. Penicillin can cause
(a) Type I hypersensitivity
(b) Type I and II hypersensitivity
(c) Type I, II and III hypersensitivity
(d) Type I, II, III and IV hypersensitivity
10. Transplantation between HLA – identical siblings belongs to
(a) Allogenic transplantation
(b) Sysgenic transplantation
(c) Autologous transplantation
(d) Xenogenic transplantation

PART B –( 5 * 5 = 25 MARKS )
ANSWER ALL QUESTION. CHOOSING EITHER (a) OR (B)

11. (a) Define Rh factor
Or
(b) Define innate immunity

12. (a) describe secondary lymboid organs
Or
(b) Detail about B cells.

13. (a) Adjuvants ; what are they?
Or
(b) Detail about vaccine.

14. (a) Explain complex fixation.
Or
(b) Illustrate invivo methods in skin test.

15. (a) Explain the mechanism of MHC I molecule.
Or
(b) Explain mechanism involved in graft rejection.

PART C –( 5 * 8 = 40 MARKS )
ANSWER ALL QUESTION. CHOOSING EITHER (a) OR (B).

16. (a) Explain function of the cell and organ immune system.
Or
(b) Write a note on blood groups
.
17. (a) Draw a diagram to describe the different steps in phagocytosis of a bacterium.
Or
(b) Describe cytokines.

18. (a) Describe the various antigen – antibody reaction in detail.
Or
(b) Distinguish paratope and epitope.

19. (a) What are the three function of antibodies?
Or
(b) Brief notes in RIA.

20. (a) How does xenograft from isograft?
Or
(b) Distinguish Autograft and Allograft.


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