GUIDELINES (Effective from July, 2005) Introduction The Restructured B.Sc. Programme in Physical Sciences, Life Sciences, Applied Physical Sciences and Applied Life Sciences will come into effect from July, 2005. The Programme will replace the earlier B.Sc. (General) Group A; B.Sc. (General) Group B; B.Sc. (General) in Electronic, Computer Science, Industrial Chemistry, Analytical Chemistry, Biochemistry and B.Sc. (General) in Environmental Science, Sericulture, Agrochemicals and Pest Control. The Academic Council of the University of Delhi adopted the report of the Empowered Committee on Restructuring of the Undergraduate Science Programmes set up by the Vice-Chancellor in its meeting held on 11 and 12 October, 2004. Subsequently, the syllabi and readings of all Foundation Courses (Ist year) of the Restructured B.Sc. Programme in Physical Sciences, Life Sciences, Applied Physical Sciences and Applied Life Sciences were approved by the Academic Council in its meeting held on 17th March, 2005. Syllabi and readings for 2nd and 3rd years were approved by the Academic Council in its meeting held on 14-2-2006 and 21-4-2006. Objectives The objectives of the Restructured B.Sc. Programme are : - To provide students a broad-based exposure to the critical domains of the sciences i.e. Physicas, Chemistry, Biology, in both single science domain and multiple science domain modes; - To provide students adequate background of Mathematical Sciences, and tools and techniques such as Computer Applications, Modern Instrumentation and Electronics, and Analytical Techniques; - To enable students to enhance their technical writing and communication skills; - To provide students adequate exposure to global and local concerns that explore the many aspects of societal relevance in Environmental Science; and 2 - To permit students an opportunity to explore the multidisciplinarity in science, particularly in those emerging areas that lie at the intersection(s) of physical, chemical, life and earth sciences including such cutting-edge areas like astrobiology, theoretical biology, geophysics, molecular paleontology, biogeochemistry, etc. Keeping these objectives in view, the restructuring of B.Sc. Programme was done. The essentials of the Restructured B.Sc. Programme are given in the following pages: Structure Every candidate shall be required to take an examination at the end of the I, II, III years respectively as per the schemes given below: Scheme of Examination I YEAR Course Course Title Duration Max. Code (Hours) Marks PH 101 Physics 3 100 PH 102 Physics Laboratory 5 50 CH 103 Chemistry 3 100 CH 104 Chemistry Laboratory 6 50 BY 105a Biology or BY 105b Biology for Physical Science 3 100 BY 106a Biology Laboratory or BY106b Biology Laboratory for Physical Science 4 50 MA 107a Mathematics or MA 107b Mathematics for Life Sciences 3 100 IN 108 Laboratory : Electronics and Modern Instrumentation 4 50 } } 3 IN 109 Laboratory : Analytical Techniques 4 50 CS 110 Laboratory : Computer Science and 4 50 Informatics ES 111 Environmental Studies 2 60 HU 112 Technical Writing and Communication 2 40 in English Total Marks 800 25% of the marks in each Theory paper will be reserved for internal assessment. 50% marks in Practical Papers will be reserved for internal assessment which will include marks for performance throughout the year, record book, and viva voce (20% + 20% + 10% respectively). II Year and III Year In the II year every student shall opt for three domain courses, each domain consisting of 2 Theory papers and a Laboratory (if required). The total marks for each domain will be 300. In addition every student shall opt for either an elective course or a project of 50 marks. In the III year, the student shall continue with the same domains which he had opted in the II year; the overall distribution of marks shall be as follows : Course Course Title Duration Max. Code (Hours) Marks D1 201/301 Science Domain (1) I 3 100 D1 202/302 Science Domain (1) II 3 100 D2 203/303 Science Domain (2) I 3 100 D2 204/304 Science Domain (2) II 3 100 D3 205/305 Science Domain (3) I 3 100* D3 206/306 Science Domain (3) II 3 100* D1 207/307 Laboratory - I Science Domain (1) 3 to 6** 100 D2 208/308 Laboratory - II Science Domain (2) 3 to 5** 100 4 D3 209/309 Laboratory - III Science Domain (3) 3 to 6** 100 EL 210/310 Elective/Project 2 50 Total Marks 950 * In courses, where there is no laboratory, theory papers shall be of 150 marks. Similar distribution of marks will be there for III year. ** Practical Examinations in Chemistry/Analytical Chemistry/ Industrial Chemistry shall be of 6 hours duration; in Physics of 5 hours duration, and in all other subjects of 3 to 4 hours duration. The following combinations will be available : A. Physical Sciences 1. Physics, Chemistry and Mathematics B. Life Sciences 1. Chemistry, Botany and Zoology C. Applied Physical Sciences 1. Physics, Mathematics and Computer Science 2. Physics, Mathematics and Electronics 3. Chemistry, Industrial Chemistry and Mathophysics 4. Chemistry, Analytical Chemistry and Mathophysics 5. Mathematics, Computer Science and Operational Research 6. Mathematics, Computer Science and Statistics D. Applied Life Sciences 1. Chemistry, Biology and Environmental Science 2. Chemistry, Biology and Agrochemical & Pest Management 3. Chemistry, Biology and Sericulture 4. Chemistry, Biology and Mathophysics 5 Scheme of Examination (for different science domains) CHEMISTRY Course Course Title Duration Max. Code (Hours) Marks II Year Examination CH 201 Inorganic & Physical Chemistry 3 100 CH 202 Organic & Physical Chemistry 3 100 CH 203 Chemistry Laboratory-I 6 100 III Year Examination CH 301 Inorganic & Physical Chemistry 3 100 CH 302 Organic & Physical Chemistry 3 100 CH 303 Chemistry Laboratory-II 6 100 PHYSICS II Year Examination PH 201 Mathematical Physics 3 100 PH 202 Thermal Physics 3 100 PH 203 Physics Laboratory-I 6 100 III Year Examination PH 301 Electromagnetic Theory 3 100 PH 302 Modern Physics 3 100 PH 303 Physics Laboratory-II 6 100 6 MATHEMATICS Course Course Title Duration Max. Code (Hours) Marks II Year Examination MA 201 Calculus and Geometry 3 150 MA 202 Algebra and Differential Equations 3 150 III Year Examination MA 301 Real Analysis 3 150 MA 302 Algebra and Mechanics 3 150 BOTANY AND ZOOLOGY (Life Sciences I and II) II Year Examination LS 201 Biodiversity I : Plants 3 100 LS 202 Biodiversity II : Animals 3 100 LS 203 Cell Biology, Biochemistry & Immunology 3 100 LS 204 Genetics, Genomics & Molecular Biology 3 100 LS 205 Life Sciences Laboratory 4 100 LS 206 Life Sciences Laboratory 4 100 III Year Examination LS 301 Development Biology and Physiology : Plants 3 100 LS 302 Development Biology and Physiology : Animals 3 100 LS 303 Ecology and Environmental Management 3 100 LS 304 Applied Biology and Biotechnology 3 100 LS 305 Life Sciences Laboratory 4 100 LS 306 Life Sciences Laboratory 4 100 7 COMPUTER SCIENCE Course Course Title Duration Max. Code (Hours) Marks II Year Examination CS 201 Programming and Data Structures 3 100 CS 202 Computer System Architecture 3 100 CS 203 Laboratory (Based on CS 201 & CS 202) 4 100 III Year Examination CS 301 Operating Systems and Networks 3 100 CS 302 Software Engineering and Databases 3 100 CS 303 Laboratory (Based on CS. 301 & CS 302) 4 100 STATISTICS II Year Examination ST 201 Statistical Methods and Probability Theory 3 100 ST 202 Applied Statistics 3 100 ST 203 Statistics Laboratory-I 4 100 III Year Examination ST 301 Statistical Inference 3 100 ST 302 Sample Surveys and Design of Experiments 3 100 ST 303 Statistics Laboratory-II 4 100 OPERATIONAL RESEARCH II Year Examination OR 201 Optimization 3 150 OR 202 Inventory Management and Queueing Theory 3 150 8 Course Course Title Duration Max. Code (Hours) Marks III Year Examination OR 301 Reliability and Statistical Quality Control 3 150 OR 302 Forecasting and Case Studies 3 150 ELECTRONICS II Year Examination EL 201 Analog and Digital Circuits 3 100 EL 202 Semiconductor Devices and Fabrication 3 100 EL 203 Electronics Lab-I 4 100 III Year Examination EL 301 Electronic Communication 3 100 EL 302 Microprocessors and Micro Controllers 3 100 EL 303 Electronics Lab-II 4 100 INDUSTRIAL CHEMISTRY II Year Examination IC 201 Industrial Chemicals & Environment 3 100 IC 202 Fossil Fuels and Fermentation Industries 3 100 IC 203 Industrial Chemistry Lab-I 6 100 III Year Examination IC 301 Industrial Chemicals in Agriculture and Medicine 3 100 IC 302 Polymers and Instrumental Methods of Analysis 3 100 IC 303 Industrial Chemistry Lab-II 6 100 9 ANALYTICAL CHEMISTRY Course Course Title Duration Max. Code (Hours) Marks II Year Examination AC 201 Basic Principles & Laboratory Operation 3 100 AC 202 Quantitative Methods of Analysis 3 100 AC 203 Analytical Chemistry Lab-I 6 100 III Year Examination AC 301 Separation Methods in Analytical Chemistry 3 100 AC 302 Instrumental Methods Analysis 3 100 AC 303 Analytical Chemistry Lab-II 6 100 ENVIRONMENTAL SCIENCE II Year Examination ES 201 Concepts in Ecology 3 100 ES 202 Natural Resource Management 3 100 ES 203 Environmental Science Lab-I 4 100 III Year Examination ES 301 Environmental Concerns and Health 3 100 ES 302 Environmental Protection and Management 3 100 ES 303 Environmental Science Lab-II 4 100 BIOLOGY II Year Examination BIO 201 Biology of Animals : Form, Structure and Function 3 100 BIO 202 Biology of Plants : Form, Structure and Function 3 100 BIO 203 Biology Lab-I 3 100 10 Course Course Title Duration Max. Code (Hours) Marks III Year Examination BIO 301 Cell & Molecular Biology and Development Biology 3 100 BIO 302 Genetics, Biotechnology and Immunology 3 100 BIO 303 Biology Lab-II 3 100 AGROCHEMICALS AND PEST MANAGEMENT II Year Examination ACP 201 Agricultural Botany, Plant Pathology and weeds 3 100 ACP 202 Fertilizers, herbicides, fungicides 3 100 ACP 203 Agrochemicals and Pest Management Lab-I 4 100 III Year Examination ACP 301 Applied Entomology 3 100 ACP 302 Insecticides, Pesticide Formulation, Analysis, Quality Control 3 100 ACP 203 Agrochemicals and Pest Management Lab-II 4 100 MATHOPHYSICS II Year Examination MP 201 Mathematics-I 3 150 MP 202 Thermal Physics and Electromagnetism 3 100 MP 203 Physics Lab-I 4 50 III Year Examination MP 301 Mathematics-2 3 150 MP 302 Optics, Electronics and Modern Physics 3 100 MP 303 Physics Lab-II 4 50 11 SERICULTURE Course Course Title Duration Max. Code (Hours) Marks II Year Examination SC 201 General Sericulture, Soil Science 3 100 SC 202 Mulberry & Silkworm Studies 3 100 SC 203 Sericulture Lab-I 4 100 III Year Examination SC 301 Sericulture Crop Improvement and Management 3 100 SC 302 Silkworm Seed Technology and Silk Technology 3 100 SC 303 Sericulture Lab-II 4 100 One Elective subject in II year may be chosen out of the following : Economics/Entrepreneurship/Organizational Behaviour/Psychology/ Financial Accounting/Financial Management or a Project of equivalent weightage in any one of these elective subjects. One Elective subject in III year may be chosen out of the following : Green Chemistry/Polymer Science/Biotechnology/Forensic Science/ Earth System Science/Intellectual Property Rights/Computational and Discrete Mathematics*/Mathematical Methods in Life Sciences. *Only for students of B.Sc. Physical Sciences/Applied Physical Sciences. 12 Promotion Rules 1. The minimum marks required to pass the I year examination shall be 36% in the aggregate of all the Theory papers taken together and 36% in the aggregate of all the Practical papers taken together. The candidate shall have to secure 36% marks separately in the University examination, as well as in the total of the University examination and internal assessment. 2. The minimum marks required to pass the II year or III year examination in the three subjects of Science Domains shall be 36% in the aggregate of the Theory papers taken subject-wise and 36% in the Practical examination in each subject, and 36% in the Elective/ Project in each year separately. The criteria will be applied separately to the University examination as well as in the total of the University examination and internal assessment. 3. At the end of II year, a candidate, who has secured pass marks (separately in Theory and Practical) in at least 2 of the Science Domains and has secured 25% marks in the aggregate including the elective subject/project may be permitted to proceed to the III Year class, and take subsequently the examination in the remaining subject of II year (in which he has not secured the pass marks) along with the University examination of the III year. 4. At the end of the III year, a candidate, who has not passed the third year examination, but has secured at least 36% marks in any subject/subjects (Theory and Practical separately for each subject) will be exempted for reappearing in those subjects. 5. The successful candidate will be classified on the combined results of I, II and III year examinations as follows : (a) First Division : 60% Marks or more in the aggregate (b) Second Division : 50% Marks or more in the aggregate (c) Third Division : All others Note : Candidates who have failed or have been absent in any year of the B.Sc. Examination may be allowed to reappear at the examination on being enrolled as ex-student in accordance with the rules and regulations prescribed in that behalf irrespective of whether they had secured the minimum pass marks in the practical papers. 13 Candidates who have already secured the minimum pass marks in the practical papers and, or Project Report/Field Work Report at a previous examination shall not be allowed to reappear in the practical papers and Project Report/Field Work Report as the case may be. Attendance Subject to the provisions of Ordinance VII-Conditions for Admission to Examination : a candidate for the B.Sc. I year Examination shall not be deemed to have satisfied the required conditions of attendance unless he has attended, in all the subjects of I year taken together, not less than two-thirds of the lectures and practicals, held in the college. In the II and III year the student should have attended not less than two-thirds of the lectures and practicals separately, held in the college in each academic year. Provided that a student of the I year class who does not fulfill the required conditions of attendance as provided in the Clause above, but has attended, in all the subjects taken together, not less than 40 per cent of lectures and practicals, held during the I year, may, at the discretion of the Principal of the College concerned, be allowed to appear at the Part I Examination; but such a candidate shall be required to make up the deficiency of lectures and/or practicals, as the case may be, of the I year, during the II year. Provided further that a student of the II year class who does not fulfill the required conditions of attendance as above, but has attended in all the subjects taken together, not less than 40 per cent of the lectures and practicals, separately, held during the II year class, may, at the discretion of the Principal of the College concerned, be allowed to appear at the Part II examination provided that he makes up the deficiency of the II year by combining the attendance of the first year class. Provided further that a student of the II year class, who was short of attendance at the end of I year class, but was allowed to appear at the I year examination, subject to his making up the deficiency of attendance during II year, and who has not been able to make up the deficiency as above, but has attended in all the subjects taken together not less than 55% of the lectures and practicals, separately, held during the I year class and the II year class, taken together, may, at the discretion of the Principal of the College concerned, be 14 allowed to appear at the II year examination, subject to his making of the deficiency of the two years taken together, as above, during the III year class. Provided further that a student of the III year class, who does not fulfill the required conditions of attendance as above, but has attended, in all the subjects taken together not less than 40% of the lectures and practicals, separately held during the III year class, shall be allowed to appear at the III year examination, if by combining the attendance of the III year with the attendance of I and II years, the candidate has put in two-thirds of attendance in all the subjects taken together, separately, in lectures and practicals held during the three years. Explanation : A student who has failed at the I year or II year or III year Examination and has rejoined the I year or II year or III year class, as the case may be shall be required to put in the requisite attendance as above, afresh, and the attendance previously put in by him for the respective year will not be taken into account. I. Notwithstanding anything to the contrary contained in the foregoing provisions : (a) A candidate for the III year examination, appearing at the examination initially, during the pendency of the course, may, with a view to improving his previous performance, be allowed to reappear, once only, at the examination in one or more subject(s) of II year, alongwith the III year examination on foregoing in writing, his earlier performance, in the subject(s) of II year. No candidates shall be allowed to re-appear in the subject(s) of II year after he has passed the III year examination. (b) A candidate who has cleared the papers of the III year examination after having appeared at the Examination initially, during the pendency of the span period, may with a view to improving his earlier performance, be allowed to re-appear, once only, at the examination in one or more subject(s) of III year either at the Supplementary Examination immediately held thereafter or if he fails to appear then at the next Annual Examination on foregoing, in writing, his previous performance in the subject(s) concerned of III year examination. 15 Explanation : No candidate will be admitted to the examination after the expiry of six years after admission to the I year class, five years after admission to the II year class and three years after admission to the III year class. Note : In the case of a candidate, who offers to reappear in any subject(s) under the aforesaid provision, on surrendering his earlier performance but fails to re-appear in the subject(s) concerned, for satisfactory reasons, the marks previously secured by the candidate in the subject(s) in which he failed to re-appear may be taken into account while determining the results of the examination held currently, on application by the candidate which should reach the University within a fortnight of the termination of the current examination. 17 SYLLABI AND READINGS 1ST Year 19 FOUNDATION COURSES PH 101 PHYSICS (70 Lectures) The primary objective of this course is to lay the foundation of Physics essential for the undergraduate students of Physical Sciences, Life Sciences and Applied Sciences. This course provides the basic understanding of core concepts in Physics and deals with their impact on modern day technology. The concepts of physics has been elaborated by some examples with the purpose of understanding the impact on other fields. Essentials of Physics Unit I Mechanics (12 L) Galilean invariance and Newton’s Laws of motion. Dynamics of a system of particles, Conservation of momentum and energy, work energy theorem. Conservation of angular momentum, torque, Motion of a particle in central force field. Kepler’s Laws, Satellite in circular orbit and applications (Synchronous satellite, GPS, Artificial gravity, apparent weightlessness). Physiological effects of acceleration and angular motion. Unit II Special Theory of Relativity (6 L) Constancy of speed of light, postulate of Special theory of relativity, length contraction, time dilation, relativistic velocity addition, Mass-energymomentum relations. Unit III Waves and Oscillations (8 L) Simple harmonic motion, damped and driven harmonic oscillator, coupled oscillator, energy relation and energy transfer, normal modes, Wave equation, Travelling waves, superposition principle, pulses. Doppler effect, effects of vibrations in humans, physics of hearing, heartbeat. Unit IV Modern optics (10 L) Two slit Interference, Diffraction, Resolving power, Resolution of the eye, Laser characteristics, Principle, Population inversion, Application of laser in medical science, Polarization of EM wave, Malus Law, Polarizing materials, Polarizer, Analyzer. 20 Unit V Statistical Mechanics (8) Phase space, micro and macro states, Thermodynamic probability, Concept of entropy, Maxwell-Boltzmann distribution. Connection to thermodynamics. Unit VI Electronics and Semiconductor Physics (8 L) PN junction diode, transistor, Operational amplifier, Inverting and noninverting amplifier OP-Amp as adder, subtractor, comparator, integrator and differentiator, Digital : Half adder and full adder, Multiplexer, clocked RS Flip Flop, 1-bit memory cell, J-K flip-flop, D to A converter (ladder network), Block diagram of A to D converter. Unit VII Quantum Mechanics (8 L) Inadequacy of classical mechanics, photoelectric effect, Compton scattering, wave particle duality, de Broglie hypothesis, two slit experiment with electrons, Heisenberg’s uncertainty Principle, basic postulates of Quantum Mechanics, Particle in a box. Unit VIII Applied Physics (10 L) Viscosity, Poiseuille’s equation, Application to blood flow in human body, Principal for measuring the blood pressure, Physiological effects of electric current, Electrical forces in molecular biology; DNA structure and Replication, Resting and action potential, Nerve conduction (Propagation of action potential in neuron), capacitance of axon. Nano-particles and its properties, Methods of synthesis of nanostructures- Physical & Chemical, introduction to Fullerenes and Carbon nano-tubes. Reference 1. Fundamentals of Physics, Halliday, Resnick and Walker, John Wiley. 2. Physics, Paul A. Tipler, CBS Publishers and Distributors. 3. Physics for Scientists and Engineers with Modern Physics, Serway and Beichner, Thomson, Brooks/Cole. 4. Physics (5th Edn.) : Principles with applications, Douglas C. Giancoli, Prentice Hall. 5. Physics (5th Edn.), John D. Cutnell & Kenneth W. Johnson, John Willey & Sons, Inc. 6. Plasma Physics, F. F. Chen. 7. Nanoelectronics & Information Technology, Wiley-VCH GmbH & Co. 8. Op-Amps and linear integrated circuits, Ramakant A. Gayakwad, Prentice Hall. 9. Digital Principles and Applications, A.P. Malvino and D. P. Leach, McGraw-Hill. 21 PH 102 PHYSICS LABORATORY Proposed Experiments 1. Moment of Inertia using Fly Wheel 2. g by Katers Pendulum/Free fall 3. To study the Coupled Oscillator 4. Frequency of tuning fork by Melde’s experiment 5. Single slit & Double slit diffraction using laser 6. Specific rotation of cane sugar by Polarimeter 7. Coefficient of thermal conductivity by Lees disc method using resistive heating. 8. Boltzman constant by PN junction 9. Poiseuilles method (Viscosity of fluid) 10. Characteristics of RC circuits 11. Forced Oscillation in LCR (series & Parallel) resonance circuit 12. Determination of Planks constant by LEDs 13. e/m by Bar Magnet/Magnetic focusing Reference Practical Physics, Nelson and Jon Ogborn 22 CH 103 CHEMISTRY The Primary objective of this course is to promote an understanding of the fundamental concepts of Chemistry and their applications while retaining the excitement of Chemistry. The course also emphasizes the development of problem solving skills in students. Unit I. Atomic Structure (14 L) Wave Mechanical Model of the Hydrogen Atom : Recapitulation of : Bohr’s theory and its limitations, dual behaviour of matter and radiation, De-Broglie’s relation, Hé is enberg Uncertainty principle. Need of new approach to the atomic structure. What is Quantum mechanics (wave mechanics)? Time-independent Schrodinger equation (H ?= E?) and meaning of various terms in it. Schrodinger equation for hydrogen atom. Need of polar coordinates, transformation of cartesian coordinates (x,y,z) into polar coordinates (r,?,F). Outline of various steps in the solution of the electronic Schrodinger equation for hydrogen atom. Radial and angular parts of the hydogenic wavefunctions (atomic orbitals) and their variations for 1s, 2s, 2p, 3s, 3p and 3d orbitals. Radial and angular nodes and their significance. Radial distribution functions and the calculation of the most probable distances for 1s and 2s atomic orbitals (by taking actual wavefunctions for these orbitals). Significance of quantum numbers, orbital angular momentum and quantum numbers m1 and m1. Shapes of s, p and d atomic orbitals - charge cloud diagrams and boundary surface diagrams, nodal planes. Discovery of spin, spin quantum number (s) and magnetic spin quantum number (ms). Multi-electron Atoms Recapitualation of : rules for filling electrons in various orbitals, Electronic configurations of the atoms. Stability of half-filled and completely filled orbitals, concept of exchange energy. Relative energies of atomic orbitals, Anomalous configurations. Total orbital angular momentum, Total spin angular momentum and total angular momentum, Spin-orbit coupling, Term symbols for light atoms 23 containing no unpaired electron, one unpaired electron and two nonequivalent unpaired electrons (s-s, s-p and pp electrons) and their importance (including the fine spectrum of H atom). Unit II Chemical Bonding and Molecular Structure (13 L) Ionic Bonding : Recapitualation of : the general characteristics of ionic bonding Energy considerations in ionic bonding, lattice energy and solvation energy and their importance in the context of stability and solubility of ionic compounds, Derivation of Born-Lande equation for calculation of lattice energy, Born-Haber cycle and its applications, polarizing power and polarizability, Fajan’s rules, ionic character in covalent compounds, bond moment, dipole moment, percentage ionic character. Covalent Bonding : VB Approach Recapitulation of : Lewis theory, VSEPR theory to explain the shapes of molecules, salient features of the Valence bond (VB) theory and the concept of hybridization. Shapes of some inorganic molecules and ions on the basis of VSEPR and hybridization with examples of linear, trigonal planar, square planar, tetrahedral, trigonal bipyramidal andS noCc1tah,e SderOalC a1rra, nIOgeFm,e Cn1tsO Fsuc, hX eaOs , BeCl , XeO F . NO , CO , SF , C F , XeF , IF , XeF , IF , XeF , BrF , CIO , CIO 2 2 4 3 3 2 2 2 4 1 3 2 5 4 7 6 5 3 2- 3 3 Concept of resonance, resonating structures and resonance energy in various inorganic and organic compounds. MO Approach Recapitulation of : limitations of the VB approach, salient features of the MO theory. Rules for the LCAO method, bonding and anti-bonding MOs and their characteristics for s-s-, s-p and p-p combinations of atomic orbitals, nonbonding combinations of orbitals MO treatment of homonuclear diatomic molecules of 1st period (including idea of s-p mixing) and heteronuclear diatomic molecules such as CO, NO, NO4, CN–, HF, HCI. Comparison of VB and MO approaches. - - 24 Unit III Chemical Thermodynamics (20 L) Recapitulation of : objectives and limitations of thermodynamics, state of system, state variables, thermodynamic equilibrium, thermodynamic properties, intensive and extensive properties, various types of systems and processes. First Law of Thermodynamics : Recapitulation of : First law of thermodynamics, concepts of internal energy and enthalpy. Calculation of work (w), heat (q), change in internal energy (?E) and change in enthaply (?H) for expansion or compression of ideal gases under isothermal and adiabatic conditions for both reversible and irreversible processes. Calculation of w, q, ?E, and ?H for processes involving changes in physical state. Thermochemistry : Recapitulation of : laws of thermochemistry, intenal energy and enthaply changes for physical and chemical processes including formation, neutralisation, combustion, ionisation, fusion and vaporisation. Concept of standard state and standard enthapies of formation, integral and differential enthalpies of solution and dilution. Calculation of bond energy, bond dissociation energy and resonance energy from thermochemical data. Variation of ethalpy of a reaction with temperature- Kirchhoff’s equation. Second and Third Laws of Thermodynamics : Recapitulation of : second law of thermodynamics, concepts of entropy, Gibbs free energy and Helmoltz free energy. Various statements of the second law of thermodynamics. Calculations of entropy change and free energy change for reversible and irreversible processes under isothermal and adiabatic conditions. Criteria of spontaniety, Gibbs - Helmholtz equation. Maxwell’s relations, thermodynamic equation of state. Third Law of thermodynamics : Statement of the law, calculation of absolute entropies of substances. Unit IV. Ionic Equilibria (7 L) Recapitulation of : strong, moderate and weak electrolytes, degree of ionization, factors affecting degree of ionization., ionization constant and 25 ionic product of water, ionization of weak acids and bases. pH scale, common ion effect, hydrolysis of salts, buffer solutions and solubility product. Multistage equilibria of acids and bases. Salt hydrolysis - calculation of hydrolysis constant, degree of hydrolysis and pH for different salts. Buffer solutions-buffer capacity, calculation of pH of different buffer solutions. Solubility and solubility product of sparingly soluble salts - applications of solubility product principle. Acid-base titrations : calculation of pH at various stages of different titrations, acid-base titration curves, Theory of acid-base indicators, pH changes and selection of indicators in different acid-base titrations. Unit V. Fundamentals of Organic Chemistry (13 L) Recapitulation of : Hybridization in organic compounds, classification and nomenclature of hydrocarbons and their derivatives, cleavage of covalent bondshomolysis and heterolysis. Electronic effects : Electronic effects and their applications - inductive, resonance and hyperconjugation effects. Structure and stability of reactive carbon species - carbocations, carbanions, free radicals and carbenes. Relative strengths of carboxylic acids (both aliphatic and aromatic), alcohols, phenols, amines (aliphatic, aromatic and heteroaromatic) and the effect of solvent and substituents (including their steric effects) on their strengths. Molecular Forces : Intermolecular and intramolecular forces, types of intermolecular forces and their characteristics : ion-dipole, dipole-dipole, dipole-induced dipole and dispresion (London) forces. Hydrogen bond (both intramolecular and intermolecular), Effect of inter/intramolecular forces on physical properties such as solubility, vapour pressure, melting and boiling points of different compounds. Aromaticity : Criterion of aromaticity : Huckel’s rule and its applications to aromatic (homonuclear and heteronuclear) and non-aromatic compounds. Unit VI. Stereochemistry (13 L) Recapitulation of : Meaning of stereochemistry and its importance. Optical isomerism - optical activity, plane polarized light, enantiomerism, chirality, specific molar rotation. 26 Stereoisomerism with two chiral centers : Diastereomers, mesoisomers, threo and erythro isomers. Physical and chemical properties of enantiomers and diastercomers. Resolution of racemic modification. A brief introduction to optically active compounds with no chiral center. Projection diagrams of stereoisomers : Fischer, Newman, Sawhorse and Flying Wedge projections. Illustration of interconversion of different projections with different examples. Relative Configuration : D/L designation in carbohydrates and amino acids. Absolute Configuration : R/S nomenclature of chiral centers, sequence rules of priority order. Conformational isomerism — ethane, butane, 1, 2-dihaloethane and 1, 2 diols, energy diagrams and relative stability of conformers. Ring strain in cyclopropane, cyclobutane. Baeyer strain theory and its limitations, cyclohexane and its conformers. Geometrical isomerism : cis/trans and E/Z nomenclature in olefins. 27 CH 104 CHEMISTRY LABORATORY Foundation Course Chemistry 1. Preparation of standard solutions of different molarities. 2. Estimation of oxalic acid by titrating with sodium hydroxide. 3. Estimation of sodium carbonate by titrating with hydrochloric acid. 4. Estimation of sodium carbonate and sodium bicarbonate/sodium hydroxide present together in a mixture. 5. Estimation of Fe (II) ions by titrating with KMnO4. 6. Estimation of oxalic acid by titrating with KMnO4. 7. Estimation of water of crystallization in Mohr’s salt/oxalic acid using KMnO4. 8. Estimation of Fe(II) ions by titrating with K2Cr2O7 using internal indicator. 9. Estimation of Cu(II) ions iodom etrically using Na2S2O3. 10. Detection of extra elements (N, S, C1, Br, I) in organic compounds (containing not more than one extra element). 11. Purification of organic compounds by crystallization (from water or alcohol) and distillation. 12. Determination of melting and boiling points of organic compounds. 13. Determination of heat capacity of a calorimeter directly (Heat gained = Heat lost by water) or by using known enthalpy data. 14. Determination of enthalpy of neutralization of hydrochloric acid with sodium hydroxide. 15. Determination of enthalpy of ionization of acetic acid. 16. Determination of integral enthalpy of solution of salts (KNO3, NH4Cl). 17. Verification of Hess’s law of constant heat summation. 28 Suggested Readings 1. J. D. Lee : A new Concise Inorganic Chemistry, E L. B. S. 2. F. A. Cotton & G. Wilkinson : Basic Inorganic Chemistry, John Wiley. 3. T. W. Graham Solomons : Organic Chemistry, John Wiley and Sons. 4. Peter Sykes : A Guide Book to Mechanism in Organic Chemistry, Orient Longman. 5. E. L. Eliel : Stereochemistry of Carbon Compounds, Tata McGraw Hill. 6. P. W. Atkins : Physical Chemistry, Oxford University Press. 7. G. W. Castellan : Physical Chemistry, Narosa Publishing House. Additional Reference Books 1. Douglas, McDaniel and Alexader : Concepts and Models in Inorganic Chemistry, John Wiley. 2. James E. Huheey, Ellen Keiter and Richard Keiter : Inorganic Chemistry : Principles of Structure and Reactivity, Pearson Publication. 3. F. A. Carey : Organic Chemistry, Tata Mc-Graw Hill. 4. I. L. Finar : Organic Chemistry (Vol. I & II), E. L. B. S. 5. W. J. Moore, Physical Chemistry, Prentice-Hall. 6. G. M. Barrow, Physical Chemistry, Tata McGraw-Hill. 7. R. T. Morrison & R. N. Boyd : Organic Chemistry, Prentice Hall. 29 BY 105a BIOLOGY (74 Lectures) Biology addresses three questions with regard to organisms. One, how should one explain the causation of the beildering variety in form and function that we notice in living organisms. Two, can the living process be analyzed through the concepts and techniques of Physics and Chemistry? And three, how has biology contributed to the human welfare on one hand and to understanding of the mind and matter in a larger sense on the other hand? This course looks at functional unity underlying structural diversity in living organisms. It tries to explain the origin and evolution of biological diversity. This course summarizes the essence of biology. It is a conceptualized presentation of the whole of biological science for recall and reflection. It provides a framework for further indepth study of biology for students of life sciences. It presents biology as a unitary, integrated and universal science. It combines organismic biology and reductionistic biology to provide a new theme of philosophy of biology i.e. organism. Unit I : Biological Systems & Environment (24 L) Origin of Life on Earth-perspectives Cell as a unit of Life Description of biodiversity Concept of Evolution Five kingdom classification of living organisms Hierarchy of organization of living processes and ecological concepts Systematics and phylogeny Living in Groups - Conflict and Cooperation (e.g. Social Insects, symbiosis, Parasitism, etc.) Unit II : Functional Unity and Chemical Context of living process (24 L) Cellular basis of living processes Nutritional requirements of organisms - autotrophs and heterotrophs Dynamic state of body constituents 30 Bioenergetics - generation, flow and utilization of energy; photosynthesis and respiration Patterns of growth & reproduction Introduction to structural and functional organization of genomes Regularity Networks Unit III : Biology and Human Welfare (26 L) Nutritional and Genetic disorders, Infectious diseases Clinical diagnostics - principles Enzyme technology, protein engineering and recombinant DNA Technology Transgenic microbes, plants and animals - products and applications Plant and animal tissue culture - applications Food Security - biofertilizers and aquaculture Fertility regulation - reproductive technologies Bioresource conservation Suggested Readings 1. P. H. Raven and G. B. Johnson : Biology 6th Edition, McGraw Hill (2004) 2. A. E. Magurran : Measuring Biological Diversity, Blackwell Science Ltd. (2004) 3. Lodish, H. et al. : Molecular Cell Biology, W. Freeman Publishers (2004) 4. Campbell : Biology, Benjamin Publishers 5. Wolfe : Biology : The Foundation, Wadsworth Publisher. 31 BY 106a BIOLOGY LABORATORY 1. Field Trip to any one ecosystem - practical description 2. Field Trip to botanical garden and Zoo-ex-situ conservation analysis 3. Biodiversity indices-measurement 4. Protein and Nucleic Acid Data Base - phylogenic analysis 5. Analysis of Modelling Data 6. Statistical analysis of biological Data - any one tool 7. Atomic Models of 10 biomolecules (e.g. amino acids, sugars, nucleotides, vitamins, peptides, steroids, antibiotics, fats and oils, etc.) 8. One animal behaviour experiment 9. Haemolysis - quantitation 10. Observation of Cell structure 11. Observation of Cell division (Mitosis) 12. Observation of Cell division (Meiosis) 13. One experiment in photosynthesis - quantitative measurement 14. Measurement of any one Circadian rhythm 15. One experiment on adsorption 16. Qualitative analysis of 2 sugars and 11 amino acid and 1 vitamin tablet 17. One physiological experiment, on a live animal/plant. 18. Type study of 6 representative each of plants and animals 19. Extraction and quantitation of one plant pigment / oil 20. Examination of histological sections (permanent slides) 32 BY 105b BIOLOGY FOR PHYSICAL SCIENCES (72 Lectures) Biology is the science of the living state. It is a science of the living process and of life forms. It is a historical science in more than one sense. Biology tells us the story of life on the earth. All the currently living organisms are not only connected to each other but also connected to all the ancestors who ever lived on the earth in the past. This course presents processed information on Biology in a capsular and conceptualized form to physical scientists. Unit I : Biodiversity and Evolution (24 L) Characteristics of living organisms. Origin of Life on Earth-problems and perspectives. Description of diversity of life forms, habitats and ecosystems. Hierarchy of interacting systems-molecules to Communities. Biosphere-Geosphere interactions through geological periods. Concept of Evolution- Elemental factors, speciation, phylogeny and bioinformatic tools. Mathematical modeling of any one biological phenomeon such as bioreactors, foraging behaviour, metabolic networks, population genetics etc. Unit II : Chemical Biology (24 L) Structural Diversity of biomolecules. Physical properties of biological structures. Nutritional requirements of Organisms. Metabolism, energy and work. Macromoleculs - structure and functions, Regulatory networks. Physical phenomena in biological systems - analysis of any two (e.g. membrane transport, photobiology, Body and Tissue Design, etc.) Unit III : Biology and Human Welfare (24 L) Medicinal Plants and products. Genetic Engineering, Ethical issues. Immuno-diagnostics. Immobilized enzymes and Biosensors. Fossil fuels and Biofuels. Bioimplants. Microscopy and Imaging techniques. Stem Cell technology and tissue engineering. 33 Suggested Readings 1. P.H. Raven and G. B. Johnson (2004) : Biology, 6th Edition, McGraw Hill. 2. A. E. Magurran : Measuring Biological Diversity, Blackwell Science Ltd. (2004) 3. Lodish, H. et al. : Molecular Cell Biology, W. Freeman Publishers (2004) 4. Campbell : Biology, Benjamin Publishers 5. Wolfe : Biology : The Foundation, Wadsworth Publishers. 34 BY 106b LABORATORY : BIOLOGY FOR PHYSICAL SCIENCES 1. Field Trip to any one ecosystem - practical description 2. Field Trip to botanical garden and Zoo-ex-situ conservation analysis 3. Biodiversity indices-measurement 4. Protein and Nucleic Acid Data Base - phylogenic analysis 5. Analysis of Modelling Data 6. Statistical analysis of biological Data - any one tool 7. Atomic Models of 10 biomolecules (e.g. amino acids, sugars, nucleotides, vitamins, peptides, steroids, antibiotics, fats and oils, etc.) 8. One animal behaviour experiment 9. Haemolysis - quantitation 10. Observation of Cell structure 11. Observation of Cell division (Mitosis) 12. Observation of Cell division (Meiosis) 13. One experiment in photosynthesis - quantitative measurement 14. Measurement of anyone Circadian rhythm 15. One experiment on adsorption 16. Qualitative analysis of 2 sugars and 1 amino acid and 1 vitamin tablet 17. One physiological experiment on a live animal/plant 18. Type study of 6 representative each of plants and animals 19. Extraction and quantitation of one plant pigment / oil 20. Examination of histological sections (permanent slides) 35 MA 107a MATHEMATICS (72 Lectures) The objective of this course is to lay the foundations of Mathematics required for the study of Physical Sciences. The focus is on introducing mathematical concepts using examples and problems from various science domains. Rigorous approaches including proofs and derivations are exemplified in a few topics. Visual, graphical and application oriented approaches are introduced, wherever appropriate. Unit I. Matrices (24 L) R, R2, R3 as vector spaces over R and concept of Rn. Standard basis for each of them. Concept of Linear Independence and examples of different bases. Subspaces of R2, R3. Translation, Dilation, Rotation, Reflection in a point, line and plane. Matrix form of basic geometric transformations. Interpretation of eigenvalues and eigenvectors for such transformations and eigenspaces as invariant subspaces. Matrices in diagonal form. Reduction to diagonal form upto matrices of order 3. Computation of matrix inverses using elementary row operations. Rank of matrix. Solutions of a system of linear equations using matrices. Illustrative examples of above concepts from Geometry, Physics, Chemistry, Combinatorics and Statistics. Unit II. Calculus (36 L) Sequences to be introduced through the examples arising in Science beginning with finite sequences, followed by concepts of recursion and difference equations. For instance, the sequence arising from Tower of Hanoi game, the Fibonacci sequence arising from branching habit of trees and breeding habit of rabbits. Convergenee of a sequence and algebra or convergent sequences. Illustration of proof of convergence of some simple sequences such as (–1)n/n, I/n2, (1+1/n)n, sin n/n, xn with ?x? < 1. Graphs of simple concrete functions such as polynomial, trigonometric, inverse trigonometric, exponential, logarithmic and hyperbolic functions arising in problems or chemical reaction, simple pendulum, radioactive decay, temperature cooling/heating problem and biological rhythms. 36 Successive differentiation. Leibnitz, theorem. Recursion formulae for higher derivative. Functions of two variables. Graphs and Level Curves of functions of two variables. Partial differentiation upto second order. Verification of known basic solutions of wave equation, heat equation, Laplace equation and diffusion equation arising from diffusion of Potassium ions in cells. Computation of Taylor’s Maclaurin’s series of functions such as ex, log (1 + x), sin (2x), cos x. Their use in polynomial approximation and error estimation. Formation and solution of Differential equations arising in population growth, radioactive decay, administration of medicine and cell division. Unit III. Statistics (12 L) Elementary Probability and basic laws. Discrete and Continuous Random variable, Mathematical Expectation, Mean and Variance of Binomial, Poisson and Normal distribution. Sample mean and Sampling Variance. Hypothesis testing using standard normal variate. Curve Fitting. Corelation and Regression. Suggested Readings 1. George B. Thomas, Jr., Ross L. Finney : Calculus and Analytic Geometry, Pearson Education (Singapore); 2001. 2. D. Waltham : Mathematics, a simple tool for Geologists, Blackwell Science, Inc., Cambridge, Massachusetts, Reprint from Chennai, India (2000). 3. Richard A. Johnson : Miller and Freund’s Probability and Statistics for Engineers, Pearson Education; 2005. 4. T.M. Apostal : Calculus, vol. 1, John Wiley and Sons (Asia) : 2002. Note : It is desirable that softwares should be used for demonstrating visual, graphical and application oriented approaches. 37 MA 107b. MATHEMATICS (72 Lectures) The objective of this course is to lay the foundations of Mathematics required for life sciences. The focus is on introducing mathematical concepts using relevant examples and in developing problem solving skills. Visual, graphic and application oriented approaches are used, wherever appropriate. Unit I Calculus (24 L) Sets. Functions and their graphs : polynomial, sine, cosine, exponential and logarithmic functions. Motivation and illustration for these functions through projectile motion, simple pendulum, biological rhythms, cell division, muscular fibres etc. Simple observations about these functions like increasing, decreasing and, periodicity. Sequences to be introduced through the examples arising in Science beginning with finite sequences, followed by concepts of recursion and difference equations. For instance, the Fibonacci sequence arising from branching habit of trees and breeding habit of rabbits. Intuitive idea of algebraic relationships and convergence. Infinite Geometric Series. Series formulas for ex, log (1+x), sin x, cos x. Step function. Intuitive idea of discontinuity, continuity and limits. Differentiation. Conception to be motivated through simple concrete examples as given above from Biological and Physical Sciences. Use of methods of differentiation like Chain rule, Product rule and Quotient rule. Second order derivatives of above functions. Integration as reverse process of differentiation. Integrals of the functions introduced above. Unit II Sequences and Multivariate Calculus (30 L) Points in plane and space and coordinate form. Examples of matrices inducing Dilation, Rotation, Reflection and System of linear equations. Examples of matrices arising in Physical, Biological Sciences and Biological networks. Sum and Produce of matrices upto order 3. Functions of two variables. Partial differentiation upto second order. Modeling and verification of solutions of differential equations arising in population growth, administration of medicine and diffusion equation arising from diffusion of Potassium ions in Cells. 38 Unit III. Statistics (18 L) Mesures of central tendency. Measures of dispersion; skewness, kurtosis. Elementary Probability and basic laws. Discrete and Continuous Random variable, Mathematical Expectation, Mean and Variance of Binomial, Poisson and Normal distribution. Sample mean and Sampling variance. Hypothesis testing using standard normal variate. Curve Fitting. Correlation and Regression. Emphasis on examples from Biological Sciences. Suggested Readings 1. H. S. Bear : Understanding Calculus, John Wiley and Sons (Second Edition); 2003. 2. E. Batschelet : Introduction to Mathematics for Life Scientists, Springer Verlag, International Student Edition, Narosa Publishing House, New Delhi (1971, 1975) 3. A. Edmondson and D. Druce : Advanced Biology Statistics, Oxford University Press; 1996. 4. W. Danial : Biostatistics : A foundation for Analysis in Health Sciences, John Wiley and Sons Inc; 2004. Note : It is desirable that softwares should be used for demonstrating visual, graphical and application oriented approaches. 39 IN 108 LABORATORY : ELECTRONICS AND MODERN INSTRUMENTATION The primary objective of this Laboratory Course is to provide hands-on exposure to basic electronic components, devices, commonly used circuit blocks, test procedures and datagathering techniques. The emphasis will be on introducing sensors and transducers used in measurement of physical quantities. The course includes basic familiarization exercises, characterization and analysis of pre-designed circuits and design applications. Students will develop a working knowledge of functional circuit blocks and integrated circuits commonly used in instrumentation. The recommended systems approach is conceptually simple and would enable the students to set up fairly advanced measurement systems for project work. List of Experiments MODULE I Unit I : Introduction to Basic Electronic Components, Test and Measurement Instruments (2 L) 1. To gain familiarity with basic electronic components. 2. To become familiar with the use of analog and digital multimeter for measurement of resistance, current and voltage in different ranges and testing of components. 3. To gain familiarity with Function Generator and cathode ray oscilloscope and (a) Investigate signal waveforms using an oscilloscope and calibrate frequency. (b) Calibrate the Audio Oscillator against main frequency. (c) Measure the phase difference between two independent signals. Unit II : DC Circuits (2 L) 1. To verify Ohm’s Law for a resistor across a power supply for a range of values of R and determine the error as R is increased to mega ohms. 40 2. To investigate the I-V characteristics of (a) Tungsten bulb, (b) diode, and (c) Solar cell. Unit III : RC Circuits (3 L) 1. Measure the time constant of an RC circuit. 2. To construct the RC differentiator and study the response to time varying signals. 3. To construct the RC integrator and study the response to time varying signals. 4. To model chemical and biological systems as RC analogs. Unit IV : Diode Circuits (2 L) 1. To design a semiconductor power supply of given rating using (a) half wave, and (b) full wave bridge recitifier circuits; investigate the affect of introducing C-filter; and study voltage regulation using a semiconductor IC. Unit V : Transistor Circuits (2 L) 1. To investigate the transistor characteristics of a common-emitter circuit and design an amplifier of given gain. 2. To study the use of transistor as a switch and a. design a light operated switch circuit using a photoresistor. b. design an opto switch using in infra-red source-sensor pair. c. design a relay driver circuit to light a bulb. MODULE II Unit VI : Operational Amplifiers (5 L) 1. To design an amplifier of given gain using Op-Amp in inverting and non-inverting configurations. 2. To measure EMF using Op-Amp. 3. To design and calibrate a differential input Op-Amp Amplifier for measuring temperature in a given range using a thermocouple. 41 4. To design and calibrate three Op-Amp instrumentation Amplifier for measuring temperature in a given range using a Resistance Temperature Device (RTD). Unit VII : Timers (2 L) 1. To design an astable oscillator of given specifications using Timer IC 555. 2. To design a monostable oscillator of given specifications using Timer IC 555. Unit VIII : Digital Gates and Combinatorial Logic Circuits (3 L) 1. To design basic logic gates OR, AND, NAND, NOT, NOR using discrete components; verify the truth tables using LED as output indicator. 2. To design a logic system for a given real life application such as water level indicator, vending machine, combinatorial lock, traffic light system, etc. 3. To study use of 4-bit binary counter; use a decoder IC to display an input 4-bit binary number as a hexadecimal number on a seven segment display. Unit IX : Data Converters (2 L) 1. To study and calibrate the circuit for a digital-to-analog converter. 2. To study and calibrate the circuit for analog-to-digital converter with LED display unit for measurement of output voltage. MODULE III Unit X : Transducer Circuits (4 L) 1. To design a photometer using a photo-diode and use this to : (a) determine how the intensity of light varies with distance from the light source (b) verify Lambert-Beer’s Law 42 2. Study of off-balance Wheatstone bridge for measurement of fractional changes in electrical resistance of resistive transducers, such as Resistive Temperature Device (RTD) or Strain Guage. Project Work Based on Microcomputer-based Data-Acquisition and Control Systems Students may be encouraged to take up projects using microcomputerbased techniques for real-time measurement of physical quantities and simple control applications. This would entail use of Analog to Digital and Digital to Analog data converter circuits along with transducer/control circuits already studied in this laboratory course. Suggested Readings 1. The Art of Electronics, P. Horowitz and W. Hill, Cambridge University Press (Cambridge, 1980). 2. Student Manual for The Art of Electronics, T. C. Hayes and P. Horowitz, Cambridge University Press (Cambridge, 1989). 3. Physics Through Experiments 1, EMF Constant and Varying, B Saraf et. al, Vikas Publishing House Pvt. Ltd. (Delhi, 1992). 4. Operational Amplifiers, George Clayton, Steve Winder and G.B. Clayton, Newnes; 5 edition (April, 2003). 5. Operational Amplified Experiment Manual, G. B. Clayton, Butterworth-Heinemann (May, 1983). 6. Data Converters, G. B. Clayton, Halsted Pr (1982). 7. Digital Design, M. Morris Mano, Morris M. Mano, Pearson Higher Education (1990). 43 IN 109 LABORATORY : ANALYTICAL TECHNIQUES The objective of this paper is to provide the students an exposure to instrumental methods and analytical techniques commonly used in Chemistry and Biology. Experimental errors and their statistical treatment Types of errors, precision and accuracy, absolute and relative uncertainty, Gaussian distribution, mean value and standard deviation. Students’ T and Q tests, confidence intervals, central charts spread sheets and finding best straight line. The students must be encouraged to perform these tests wherever possible using computational techniques. Separation Techniques 1. Chromatography (5 Lab.) (a) Separation of mixtures (i) Paper chromatographic separation of Fe3+, Al3+ and Cr3+ OR Paper chromatographic separation of Ni2+, Co2+, Mn2+ and Zn2+. (ii) Identify and separate the components of a given mixture of amino acids (glycine, aspartic acid, glutamic acid and tyrosine) by paper chromatography. (iii) Separate and identify the monosaccharides present in the given mixture (glucose and fructose) by paper chromatography. Report and Rr values. (b) Separate a mixture of Sudan Yellow and Sudan Red by T.L.C. techniques and identify them on the basis of their Rr values. (c) Chromatographic separation of the active ingredients of plant/ flower juices by TLC. (d) Separation of ortho and para-nitroaniline by Column Chromatography. 44 2. Solvent Extraction (2 Lab.) To separate a mixture of Ni2+ and Fe3+ by complexing Ni2+ with DMG and extracting the Ni2+ - DMG complex in CHCl3. Also record the absorbance of the extracted complex at A. ? max . 3. DNA Isolation (2 Lab.) Isolation of DNA from an actively growing tissue by disruption of noncovalent bonds among various macromolecules (cauliflower or onion can be used). Electroanalytical Methods : (10 Lab.) 1. Conductometry (a) (i) Determine the equivalent conductance of a weak electrolyte (acetic acid) at different concentrations. (ii) Determine the pH and conductivity of a soil sample. (b) (i) Determine the strength of the given HCI solution by titrating it against NaOH solution conductometrically. (ii) Determine the strength of the given Ch3COOH solution by titrating it against NH4OH solution conductometrically. 2. pH-Metry and Potentiometry (a) (i) Prepare buffers of (i) CH3COOH and CH3COONa (ii) Citric acid and Na2HPO4 and determine their pH values using glass electrode. (ii) Determine the pH of given aerated drinks, fruit juices, shampoos and soaps. (Use diluted solutions of soaps and shampoos to prevent damage to the glass electrode) (b) Titrate given solution of HCI with NaOH pH-metrically. (c) Determine the isoelectric point of an amino acid (e.g. glycine) by pH-metric titration with a weak acid or a weak base. 45 (d) Determine the strength of given solution of K2Cr2O7 by titrating with Mohr’s salt solution potentiometrically. 3. Electrophoresis (a) Separation of mixture of 2 or 3 amino acid viz. Glycine, arsine/ lysine, aspartic acid/glutamic acid by electrophoresis. Introduction to Spectroscopic Techniques (6 Lab.) 1. COLORIMETRY / SPECTROPHOTOMETRY (a) To plot absorbance Vs wavelength curve for a given coloured complex {Fe(SCN)2+} and identify ? max for the complex ion. (b) To draw calibration curve [Absorbance at ? max vs concentration] for various concentrations of Fe3+ in Fe(SCN)2+ complex and estimate the concentration of Fe3+ in a given solution. 2. FLAME TECHNIQUES Flame photometry : Determine the concentration of Na+ and K+ using flame photometry. Project Work Students must be encouraged to do projects using the above techniques and also the kits prepared by other Institutions such as Central Pollution Control Board, Development Alternatives. Suggested Readings 1. Vogel, Arther I. : Textbook of Quantitative Chemical Analysis- (Rev. by G. H. Jeffery) 5th Ed. - Singapore : Addison. 2. Willard, Hobert H. et al : Instrumental Methods of Analysis-6th ed. - Delhi : C.B.S. Pub., 1986. 3. Christian, Gary D.; Analytical Chemistry-6th ed., - New York-John Wiley, 2004. 4. Harris, Daniel C. : Exploring Chemical Analysis-2nd ed., - New York- W.H. Freeman, 2001. 46 CS 110 COMPUTER APPLICATIONS As application of computers plays a central role in the study of science, the course aims at familiarizing the students with basic concepts and applications of computers. The course would enable the student to make use of computers for document preparation, data analysis, visual interpretation and electronic communication. The student would also be able to develop small programs for solving scientific problems, making use of suitable tools. Unit I : Introduction : (2 Lab.) Computer Fundamentals : Logical organization of computer, memory : primary, secondary; input-output devices; keyboard, monitor, printers; data representation : bits and bytes, words, number systems : decimal, binary, octal, hexadecimal, BCD; ASCII, EBCDIC; byte codes. User Computer Interface : Functional familiarity with operating system: Linux/Windoes, security. Unit II : Presentation and Communication Tools : (16 Lab.) Document Preparation : Creating a document, entering and editing text, formating text, using spell check, applying styles and fonts, columns, tables and frames, merging and indexing, inserting links, working with other applications, inserting pictures, inserting symbols. Spreadsheet Handling : Working with worksheets : Creating a spreadsheet, entering and formating information, basic functions and formulas, creating charts, tables and graphs. Presentation Software : Creating a presentation : applying special effects (animation and sound), working with images, linking with other documents or spreadsheets. Internet Technology : Introduction to network terminology, internet and intranet, connecting to internet, internet services : telnet, ftp, www, e-mail, electronic publishing. Unit III : Programming : (12 Lab.) Introduction to Scientific Programming Environment : Introduction to High level language, problem solving using algorithmic notation, prorgramming fundamentals : input-output statements, data types and data 47 structures such as array, control structures for selection and looping, functions, introduction to files : opening, closing, reading and writing; use of geometric transformations for 2D and 3D objects, use of scientific functions such as finding derivatives, interpolation, roots, use of statistical functions such as mean, median, standard deviation, variance and histogram, use of functions for scientific visualization, introduction to molecular modeling tool kit (overview). Note : Use of Star Office is recommended as it is freely downloadable, Python to be used for programming. References http://www.opeooffice.org http://www.python.org Reference manuals of Star Office Star office Companion, Solveing Haughland, Floyd Jones, SYBEX Python : How to Program, Harvey M. Deitel & Paul J. Deitel, Prentice Hall How to Think Like a Computer Scientist : Learning with Python, Allen Downey. 48 ES 111 ENVIRONMENTAL SCIENCE (36 Lectures) This course aims to provide an overview of the environmental and natural resource system that are essential for a sustainable earth. The course emphasizes the issues related to environmental degradation affecting abiotic and biotic components with typical Indian examples. This course would also expose the students to good practices of measures adopted for effective management, and conservation of earth resources. Unit I : Introduction to the Environment (8 L) Components of the Environment & Natural Resources : Water, air, rocks, soils, sediments and living organisms; kind’s of natural resources. Levels of Ecological Organization : populations, communities, ecosystems, biomes, biosphere. Linkages within and among Components of Ecosystem : Food chain and webs, energy flow and cycling of chemical substances and other materials in ecosystem, hydrological cycle. Finiteness of resources : carrying capacity; human population and resource utilization; humanecological interrelationships. Resources and Development : Concept of Mother Earth; Conflict between development and environment; conservation and sustainable development; biodiversity. Environmental Protection, global and regional issues. Field Trip Unit II : Environmental Problems with Special Reference to India (10 L) Deforestation, soil degradation and desertification Air pollution - sources and sinks, pollutants Water pollution - sources and sinks, pollutants Soil pollution - sources and sinks Noise pollution 49 Mining related environmental problems Hazardous wastes and Radioactive Pollution Solid Wastes Disposal, Sewage Treatment and Sanitation Energy and Environment - patterns and trends in energy consumption and production Environment, Public Health and Hygiene. Field Trip Unit III : Impact of Environmental Degradation (8 L) Climate Change, Acid Rain and Damage to Forests Pollution and damage to National Heritage Monuments Radioactive Pollution, Nuclear winter and Mass Destruction Biodiversity, Losses and Species Extinction Oil Spills and Loss of Marine Life Natural Disasters - earthquakes and seismicity, floods, drought, Tsunamis and cyclones Reduction of Agriculture Productivity and Pastures and associated Food Security Concerns, Poverty and Famines. Field Trip Unit IV: Management of Environment and Sustainability (10 L) Technological choices in agriculture, industrial and domestic spheres, population, resources and sustainability. Technological solutions : pollution abatement technologies, clean technologies, alternate sources of energy; afforestation programmes (Social forestry, agroforestry and alley cropping); restoration technologies for ecological rehabilitation of degraded lands; water shed management; bioremediation; resource recycling and biotechnologies. Environmental auditing, environmental impact assessment and environmental laws. 50 Field Trip Suggested Field Activities and Visits 1. Walk/boating along Yamuna Banks 2. Sites of dumping of coal ash by power houses 3. Visit to Pollution Monitoring Units 4. Visit to Biodiversity Park 5. Visit to Bird Sanctuary. Suggested Readings 1. Miller, G.T. Jr. Environmental Science. 10th Ed. Thomson/Brooks- Cold (Indian edition available) 2004 2. Roy, S. Environmental Science. Publishing Syndicate, Kolkata 2003 3. Singh, H.R. and Neeraj Kumar. Ecology and Environmental Science. Vis. Jallandhar 2004 4. Shormila Mukherjee. Fragile environment. Manak Pub. Pvt. Ltd. Laxmi Nagar, Delhi, 2004. 51 HU 112 TECHNICAL WRITING AND COMMUNICATION IN ENGLISH This is an enabling course which aims to give students a formal and methodical exposure to technical writing and professional communication skills. The approach is practical in nature. The course will provide an opportunity to use computer-based tools for effective document preparation and presentation. Unit I (10 L) Communication : Language and communication, differences between speech and writing, distinct features of speech, distinct features of writing. Unit II (10 L) Writing Skills; Selection of topic, thesis statement, developing the thesis; introductory, developmental, transitional and concluding paragraphs, linguistic unity, coherence and cohesion, descriptive, narrative, expository and argumentative writing. Unit III (10 L) Technical Writing : Scientific and technical subjects ; formal and informal writings; formal writings/reports, handbooks, manuals, letters, memorandum, notices, agenda, minutes; common errors to be avoided. Suggested Readings 1. M. Frank. Writing as thinking : A guided process approach, Englewood Cliffs, Prentice Hall Reagents. 2. L. Hamp-Lyons and B. Heasely : Study Writing; A course in written English. For academic and professional purposes, Cambridge Univ. Press. 3. R. Quirk, S. Greenbaum, G. Leech and J. Svartik : A comprehensive grammar of the English language, Longman, London. 4. Daniel G. Riordan & Steven A. Panley : “Technical Report Writing Today” - Biztaantra. 52 Additional Reference Books 5. Daniel G. Riordan, Steven E. Pauley, Biztantra : Technical Report Writing Today, 8th Edition (2004). 6. Contemporary Business Communication, Scot Ober, Biztantra, 5th Edition (2004). 53 2nd Year 55 CHEMISTRY CH 201 INORGANIC AND PHYSICAL CHEMISTRY (3 Lectures per week) Unit I : (34 L) General Principles of Metallurgy Chief modes of occurrence of metals based on standard electrode potential. Hydrometallurgy. Ellingham diagrams. Methods of refining and purification of metals : electrolytic, oxidative refining. Kroll Process, Parting process, van Arkel - de Boer method, Mond process. 5 s- and p - Block Elements Periodicity in s - and p- block elements w.r.t. electronic configuration, atomic and ionic size, ionization enthalpy, electron gain enthalpy, electronegativity (Pauling and Mullikan scales), allotropy and catenation, oxidation states (with special reference to elements in unusual and rare oxidation states like in alkalides, carbides, nitrides), inert pair effect, diagonal relationship and anomalous behaviour of first member of each group. Solutions of alkali metals in liquid ammonia and their properties. Complexes of s- and p- block elements. Hydrides and their classification (ionic, covalent and interstitial), structure and variations in properties with respect to stability, reducing behaviour and acid/base strength of hydrides of various Groups of p- block elements. A study of the following compounds with emphasis on structure, bonding and their important properties like oxidation/reduction, acidic/basic nature and their applications in industrial, organic and environmental chemistry: Hydrides of nitrogen (NH3, N2H4, N3H2 NH2OH) Oxides and oxo-acids of N. P. S and Cl. Halides - SiCl4, Sncl2, PCl3, PCl5, SOCl2, SO2Cl2. 23 Inorganic Polymers : Comparison between inorganic and organic polymers. Synthesis, structural aspects and applications of borazine, silicates, silicones and phosphazine. 6 56 Unit II : Bio-Inorganic Chemistry (11 L) A brief introduction to bio-inorganic chemistry. Role of metal ions present in biological systems with special reference to Na2, K2,Mg2- ions : Na/K pump; role of Mg2 ions in energy production transmission of impulses along nerve fibers and chlorophyll; role of ca2- ions in blood clotting, muscle contraction, stabilization of protein structures and structural role (bones). 5 Chemistry Toxicity : Toxicity of As, Cd, Pb. Hg, CO, NOx, SOx, H2S, their sources of contamination. Causes of toxicity (biochemical effects) and antidotes. 6 Unit III : States of Matter (13 L) Kinetic Theory of Gases Collision cross section, collision number, collision frequency, collision diameter and mean free path of molecules and also effects of temperature and pressure on them (for ideal gases). Viscosity of gases, relation between mean free path and coefficient of viscosity. Temperature and pressure dependence of coefficient of viscosity. Degrees of feedom of motion, principle of equipartition of energy. Maxwell distribution laws of molecular velocities and molecular energies (only graphical representation - derivation not required) and their importance. Temperature dependence of these distributions. Most probable, average and root mean square velocities (no derivation). Real gases, compressibility factor, deviation of real gases from ideal behaviour. Causes of this deviation van der Waals equation of state for real gases. Brief mention of various other equations of state of real gases (viz. the Virial equation and the Berthelot equation). Calculation of Boyle temperature from van der Waals equation of state. Principles of liquefaction of gases. Critical phenomena, critical constants and their calculation from van der Waals equation. Andrews isotherms of CO2. Continuity of states. Law of Corresponding States. Derivation of the reduced equation of state and its physical significance. 10 Liquids Surface tension and its determination using stalagmometer. Viscosity of a liquid and determination of coefficient of viscosity using Ostwald viscometer. Effect of temperature on surface tension and coefficient of viscosity of a liquid (qualitative treatment only). 3 57 Unit IV: Systems of Variable Composition and Solutions (12 L) Systems of Variable Composition Partial molar quantities and their physical significance. Chemical potential, variation of chemical potential with temperature and pressure. Free Energy and entropy of mixing of ideal gases. Gibbs - Duhem equation. 2 Solutions Thermodynamics of Ideal Solutions : ideal Solutions and Raoult’s law. Deviations from Raoult’s law - non-ideal solutions. Isothermal vapour pressure - composition (and isobaric boiling point-composition) curves of ideal and non-ideal solutions. Distillation of ideal and non-ideal solutions. Lever rule. Azeotropes., Partial miscibility of liquids. Critical solution temperature. Immiscibilty of liquids. Principle of steam distillation. 5 Colligative Properties of Dilute Solutions Thermodynamics of dilute solutions : thermodynamic derivations (from chemical potential) of the expressions in terms of molailty for the elevation in boiling point, depression in freezing point and osmotic pressure of a dilute ideal solution. Relationship between different colligative properties. Determination of molar masses of non-volatile solutes (non-electrolytes). Colligative properties of electrolytic solutions, van’t Hoff factor and its applications. 5 58 CH 202 ORGANIC AND PHYSICAL CHEMISTRY (3 Lectures per week) Unit - I : Organic Reactions and their Mechanisms (Substitution, Addition, Elimination, Rearrangement); Oxidation and Reduction Reactions (40 L) Addition Reactions Alkenes and Alkynes (Ethene, Propene, Ethyne and Propyne) : Hydrogenation, Halogen addition, hydrohalogenation (Markovnikov’s and anti Markovnikov’s), hydration, hydroboration, hydroxylation (cis and trans), oxymercuration - demercuration, ozonolysis and carbene addition. Reactivity of alkenes vs alkynes. Alkadienes (Butadiene) : Hydrogenation, halogen addition and Diels-Alder reaction. Aromatic hydrocarbons (Benzene) : Hydrogenation, halogen addition and ozonolysis. Aldehydes and ketones (Formaldehyde, acetaldehyde, benzaldehyde and acetone) : Addition reaction with sodium bisulphite, hydrogen cyanide and alcohols. Addition-elimination reactions with ammonia and its derivatives as well as the following name reactions - Aldol, Cross - Aldol, Perkin, Claisen, Knoevengel, Wittig, Cannizzaro, Cross Cannizzaro and Benzoin condensation. 9 Substitution Reactions (a) Free radical substitution reactions : Halogenation of alkanes, allylic compounds and alkyl benzenes. (b) Nucleophilic substitution reactions : Alkyl, Allyl and Benzyl halides- Substitution of halogen by important nucleophiles. Mechanism of SN1 and SN2 reactions (stereochemistry, nature of substrate, nucleophile and leaving group). Aryl halides : Substitution reaction of chlorobenzene by SnAr and benzyne machanism. 59 Benzenediazonium chloride : replacement of diazo group (nucleophilic and free radical mechanism). Benezene sulphonic acid : substitution of sulphonic acid group by important reagents. Alcohols, Phenols and Amines : substitution of active hydrogen. Replacement of hydroxyl group in alcohols (using PCL5, SOCl2, and Hl), glycol and glycerol (using Hl). Carboxylic acid derivatives : Hydrolysis. Ethers - cleavage of ethers by hydroiodic acid. (c) Electrophilic substitution reactions (Aromatic compounds) : General mechanism of electrophilic substitution, directive influence of substituents and the following reactions; Nitration. Halogenation and sulphonation, Alkylation (Friedal Craft’s alkylation). Acylation (Friedal Crafts and Hoesch condensation), Formylation (Gattermann, Gattermann - Koch and Reimer- Tiemann reactions) Carboxylation (Kolbe-Schmidt reaction) and coupling of benzenediazonium chloride with phenols and amines. 16 Elimination Reactions Alkyl halides (dehydrohalogenation), vicinal dihalides (dehalogenation), alcohols (dehydration) — Quaternary ammonium salts (Hofmann’s elimination) and Cope elimination (Amine-oxides). Mechanism of E1 and E2 reactions (nature of substrate and base) and elimination vs substitution. 5 Rearrangement Reactions Pinacol - Pinacolone, Hofmann bromamide. Curtius, Schmidt, Lossen, Beckmann, Benzil - Benzilic acid. Benzidine. Fries rearrangement. cumene hydroperoxide (phenol from cumene). 5 Oxidations Aromatic side chain oxidation with potassium permanaganate, potassium dichromate, chromium trioxide-acetic anhydride. Etard reaction. Alcohols with potassium dichromate, potassium permanganate, catalytic dehydrogenation and Oppenauer oxidation, Oxidation of 1.2 - diols with periodic acid and lead tetraacetate. Aldehydes with Chromic acid, potassium permanganate, selenium dioxide, Tollen’s and Fehling solution. 60 Ketones with Potassium permanganate, selenium dioxide, sodium hypoiodite (iodoform reaction) and Baeyer-Villiger oxidation. Amines with Hydrogen peroxide. Trifluoroperoxy acetic acid and peroxydisulphuric acid. 3 Reductions Aldehydes and ketones : Catalytic hydrogenation, reduction with sodium borohydride, lithium aluminium hydride. Clemmensen, Wolff-Kishner, Meerwein Ponndorf-Verley, Bouveault-Blane reduction and formation of pinacols. Carboxylic acids and derivatives : Lithium aluminium hydride, Sodiumethanol, Stephen’s reaction and Rosenmund reduction. Nitro benzene : Acidic, alkaline and neutral reducing agents, Lithium aluminium hydride and electrolytic reduction. Diazonium salts : Benzenediazonium chloride - reduction to aniline and phenyl hydrazine. 2 Unit II : Active Methylene Compounds and Grignard Reagents (5 L) Active methylene compounds - preparation, properties and synthetic applications of Ethyl accetoacetate and diethyl malonate. 5 Grignard Reagents - preparation and reactions. Unit III : Conductance & Electrochemical Cells (16 L) Conductance Conductance and its measurement conductivity, equivalent and molar conductivity. Explanation of variation of conductivity, equivalent and molar conductivity with dilution of weak and strong electrolytes. Kohlrausch law of independent migration of ions. Transference number and its experimental determination using Hittorf and Moving boundary methods Ionic velocity and ionic mobility. Applications of conductance measurements : determination of degree of ionisation of weak electrolyte, solubility and solubility product of sparingly soluble salts, ionic product of water, hydrolysis constant of a salt. Conductometric titrations (only acidbase). Activity and activity coefficient of strong electrolytes Ionic strength of a 61 solution. Debye Huckel theory of activity coefficients (derivation not required. 8 Electrochemical Cells Reversible and Irreversible cells. Measurement of EMF of a cell : Thermodynamics of a reversible cell : calculation of thermodynamic properties ?G, ?H and ?S from EMF data. Nernst equation Types of electrodes (including reference electrodes such as glass and calomel electrodes). Standard electrode potential. Determination of standard EMF of a cell. Calculation of equilibrium constant from EMF data. Concentration cells (both electrode and electrolytic) with transference and without transference. Liquid junction potential. pH determination using hydrogen electrode, glass electrode and quinone-hydroquinone electrode. Potentiometric titrations. Unit IV : Chemical Equilibrium & Phase Equilibrium (9 L) Chemical Equilibrium Thermodynamic derivation of the law of chemical equilibrium. van’t Hoff reaction isotherm ?GO = - RT In KP. Distinction between ?G and ?GO, Le Chatelier’s principle, Thermodynamic treatment of temperature and pressure dependence of equilibrium constant - van’t Hoff equation. Phase Equilibrium Explanation of the terms : phase (P), component (C) and degree of freedom (F), Criteria of phase equilibria. Gibbs Rule (F + P = C + 2) and its themodynamic derivation. Derivation of Clausius - Clapeyron equation and its importance in phase equilibria. Phase diagrams of one component systems (water and sulphur systems) and two component system (leadsilver system to explain desilverisation of lead). Nernst Distribution Law (derivation not required) and its applications. 62 CH 203 CHEMISTRY LABORATORY - I Note : Practical examination will include three exercises - one each out of the following physical, organic and inorganic chemistry experiments. 1. Determination of critical solution temperature for phenol - water system. 2. Comparison of osmotic pressures of different concentrations of aqueous solutions of sugars, salts by measuring the heights to which the solvents rise. 3. Determination of surface tension of a liquid using a stalgmometer. 4. Determination of relative and absolute viscosities of a liquid using on Ostwald viscometer. 5. Preparation of the following compounds : a. Carboxylic acids by alkaline hydrolysis of an Ester/Amide b. Benzoyl derivatives of amines and phenols. c. m-Dinitrobenzene from nitrobenzene. d. Osazone of glucose / fructose 6. Following organic transformations using biocatalysts a. Fermentation of sucrose with yeast and lab test of the alcohol so formed (iodoform test). b. Hydrolysis of an ester. c. Organic estimation of : (i) Aniline by Bromate - Bromide method (ii) Glycine by Sorensen’s method 7. Semi-micro qualitative analysis using H2S/ PTC / Thioacetamide or any other reagent of mixtures containing not more than six ionic species (three anions and three cations and excluding insoluble salts and interfering anions) out of the following. Spot tests should be carried out wherever feasible : - - - - + + + + + - - - - - - - + + + + + + + + + + + + + 2 3 4 2 3 2 2 3 2 3 2 2 3 2 2 2 2 2 3 2 2 2 3 3 2 3 2 2 4 ,1 , , , , , , , , , , , , , , , , , , , , , , , , , Br NO SO Zn Ba Sr Ca K CO S SO S O NO CH COO Cl NH Pb Ag Bi Cu Cd Sn Fe Al Co Cr Ni Mn 63 Suggested Readings 1. J. D. Lee : A New Concise Inorganic Chemistry, E.L.B.S. 2. F.A. Cotton & G. Wilkinson : Basic Inorganic Chemistry, John Wiley. 3. D. F. Shriver and P. W. Atkins : Inorganic Chemistry, Oxford University Press. 4. Gary Wulfsberg : Inorganic Chemistry, Viva Books Pvt. Ltd. 5. T. W. Graham Solomons : Organic Chemistry, John Wiley and Sons. 6. R. T. Morrison & R. N. Boyd : Organic Chemistry, Prentice Hall. 7. I. I. Finar : Organic Chemistry (Vol. I & II) E. L. B. S. 8. Jerry March : Advanced organic Chemistry, John Wiley & Sons 9. P. W. Atkins : Physical Chemistry, Oxford University Press. 10. G. W. Castellan : Physical Chemistry, Narosa Publishing House. Additional Reference Books 1. K. M. Mackay and R. A. Mackay, Introduction to Modern Inorganic Chemistry, Intertext. 2. James E, Hubeey, Ellen Keiter and Richard Keiter : Inorganic Chemistry : Principles of Structure and Reactivity, Person Publication. 3. Peter Sykes : A Guide Book to Mechanism in Organic Chemistry, Orient Longman. 4. F. A. Carey : Organic Chemistry, Tata Mc-Graw Hill 5. W. J. Moore : Physical Chemistry, Prentice-Hall. 6. G. M. Barrow - Physical Chemistry, Tata McGaw-Hill. 64 PHYSICS PH 201 METHEMATICAL PHYSICS (Physical Sciences / Applied Physical Sciences) (70 Lectures) Vector analysis: (18 L) Scalar and vector products. Vector calculus; gradient, divergence and curl of a vector Gauss’ theorem and stokes’ theorem. Line, surface and volume integrals. Line, surface, volume elements and ?2 in cylindrical and spherical polar coordinates. Complex variables: (25 L) Complex variables, complex numbers and their graphical representation. de Moiver’s theorem, Roots of complex numbers. Euler’s formula. Functions of complex variables. Analytic functions. Multiple valued functions. Cauchy-Reimann condition. Analytic functions. Singularities. Differentiation and integration of function of complex variable. Cauchy’s integral Formula. Residue theorem. Taylor and Laurent series. Singular point, poles, essential and removable singularities. Contour integration. Special functions: (11 L) Legendre, Bessel, Hermite and laguerre functions, Generating function. Recurrence relations. Legendre, Bessel and Hermite differential equations. Orthogonality. Gamma functions. Fourier series: (6 L) Fouries series, Dirichlet conditions. Since and cosine series. Applications to square wave, triangular wave. Half wave and full wave rectifier and simple functions. Integral transform: (10 L) Fourier transform: Sine and cosine transform. Solution of one- dimensional differential wave equation. 65 Laplace transform: transform of elementary functions, derivatives and integrals, unit step function, periodic functions. Translation, substitution. Solution of first and second order differential equations with constant cofficients. Advanced Engineering Mathematics, Erwin Kreyszing, John Wiley & Sons, Inc. Schaum outline series (Vector analysis, Complex variable, Fourier Analysis), Tata McGraw-Hill. Mathematical Physiscs; a modern introduction to its foundation, Sadri Hassani, Springer-Verlag Advance Engineering Mathematics, C. Ray Wylie and Louis C. Barrett, Tata McGraw-Hill Edition. 66 PH 202 THERMAL PHYSICS (Physical Sciences / Applied Physical Sciences) (70 Lectures) Thermodynamics: (15 L) Zeroth and first of thermodynamics. Reversible and irreversible processes. Carnot’s cycle, Carnot’s theorem. Second law of thermodynamics and entropy. Thermodynamic temperature. Entropy change in reversible and irreversible processes. Thermodynamic potentials. Enthalpy, Gibbs’ and Helmholtz’s functions. Joule’s Thomson effect, cooling of Van der Waals gas, Maxwell relations and their applications. Claussius-Clapyron equation. Kinetic theory: (15 L) Derivation of Maxwell’s law of distribution of velocities and its experimental verification. Mean free path. Law of equipartition of energy and its applications to specific heat of gases. Transport phenomenon ; viscosity, conduction and diffusion. Brownian motion. Statistical mechanics: (5 L+20 L+15 L) Micro and Macro states, Thermodynamic probability. Partition Function, Entropy, Maxwell-Boltzmann distribution, Thermodynamic properties of ideal-gas Bose-Einstein Distribution Function, Thermodynamic properties of photon gas, Bose Einstein Condensation and its experimental verification (qualitative treatment only). Bose derivation of Planck’s Law. Its special cases i.e. Rayleigh Jeans and Wein’s displacement law. Stefan-Boltzman law Fermi Dirac Statistics: Fermi Dirac Distribution function, Completely and Strongly degenerate Fermi gas. Specific heat of metals. Relativistic degenerate Fermi gas. Chandrashekhar mass limit for white dwarf stars. Thermodynamics and Statistical Mechanics, Greiner, Springer Heat and Thermodynamics, Zemanskay and Dittman, Mc Graw Hill Statistical Mechanics, R.K. Patharia, Pergamin press, Oxford 67 PH 203 PHYSICS LABORATORY - I (Physical Sciences/Applied Sciences) 1. Determination of Stefan’s constant. 2. Thermal conductivity of good conductor by Searles method 3. Temperature coefficient of resistance by PRT 4. Calibration of Thermocouple. 5. Study of BG (charge sensitivity, CDR) 6. High resistance by Leakage method 7. Ratio of two capacitances by De-Saughty bridge 8. Coefficient of Mutual inductance by absolute method 9. Determination of ? of light by Newton’s ring. 10. Low resistance by Carey Foster Bridge 11. Determine the Cauchy’s constant and dispersive power of Prism. 12. Determination of ? of Na light by diffraction grating. 13. To determine the ? of light by Fresnel’s biprism 14. Programming using 8085 microprocessor. Add and subract two 8-bit numbers. Multiply two 8-bit numbers. Divide two 8-bit numbers. Check the parity of a number. A Minimum of ten experiments are to be performed by each student. 68 MATHEMATICS MA 201 CALCULUS AND GEOMETRY (4 Lectures+1 tutorial a week) Total marks 150 Examination 112 Internal Assessment 38 Unit I: Geometry of complex numbers and polynomial equations (15 marks) Geometrical representation of addition, subtraction, multiplication and division of complex numbers. Lines half planes, circles, discs in terms of complex variables. Statement of the Fundamental Theorem of Algerbra and its consequences, Relation between roots and coefficients for and polynomial equation. Results about occurrence of repeated roots, rational roots, surd roots and complex roots. De Moivre’s theorem for rational indices and its simple applications. Unit II: Calculus 60 Limit and continuity of a function: (e, d) and sequential approach. Properties of continuous functions including intermediate value theorem. Differentiability. Darboux’s theorem, Rolle’s theorem, Lagrange’s mean value theorem, Cauchy mean value theorem with geometrical interpretations. Uniform continuity. Definitions and techniques for finding asymptotes singular points, concavity, convexity, points of inflexion for functions. Tracing of standard curves. Integration of irrational functions. Reduction formulae. Rectification. Quadrature. Volumes. Surfaces of revolution. Unit III: Geometry and Vector Calculus 37 Techniques for sketching parabola, ellipse and hyperbola. Reflection properties of parabola, ellipse and hyperbola . Classification of quadratic equations representing lines, parabola, ellipse and hyperbola. Polar equations of conic sections. 69 Differentiation of vector valued functions, gradient, divergence, curl and their geometrical interpretation. Spheres, Cylindrical surfaces. Illustrations of graphing standard quadric surfaces like cone, ellipsoid. Recommended Books 1. H. Anton, I. Bivens and S. Davis: Calculus, John Wiley and Sons (Asia) Pte. Ltd. 2002. 2. R.G. Bartle and D.R. Sherbert : Introduction to Real Analysis , John Wiley and Sons (Asia) Pte, Ltd; 1982 3. A.I. Kostrikin: Introduction to Algebra, Springer Verlag, 1984. Further References 1. K.A. Ross: Elementary Analysis- The Theory of Calculus Series- Undergraduate Texts in Mathematics, Springer Verlag, 2003 2. G.B. Thomas and R.L. Finney: Calculus and Analytic Geometry, Pearson Education (Singapose), 2001. 3. S.L. Salas, E. Hille and G.J. Etgen: Calculus of One and Several Variables John Wiley & Sons, Inc., 1999. 70 MA 202 ALGEBRA AND DIFFERENTIAL EQUATIONS (4 Lectures + 1 tutorial per week) Total marks: 150 Examination 112 Internal Assessment 38 Unit I : Groups, Rings and Vector spaces 6 Groups: Definition and examples of groups, examples of abelian and nonabelian groups: the group Zn of integers under addition modulo n and the group U (n) of units under multiplication modulo n. Cyclic groups from number systems, complex roots of unity, circle group, the general linear group GLn (n,R), groups of symmetries of (i) an isosceles triangle, (ii) an equilateral triangle, (iii) a rectangle, and (iv) a square, groups of transformations in a plane, the permutation group Sym (n), Group of quaternions, crystallographic groups. Subgroups, cyclic subgroups, the concept of a subgroup generated by a subset and the commutator subgroup of group, examples of subgroups including the center of a group. Cosets, Index of subgroup, Lagrange’s theorem, order of an element, Euler and Fermat’s theorem, order of HK where H and K are subgroups. Normal subgroups: their definition, examples, and characterizations, Quotient groups. Rings: Definition an examples of rings, examples of commutative and noncommutative rings: rings from number systems, Zn the ring of integers modulo n, ring of real quaternions, rings of matrices, polynomial rings, and rings of continuous functions. Subrings and ideals, Integral domains and fields, examples of fields: Zp, Q, R, and C. Field of rational functions. Vector spaces: Definition and examples of vector spaces. Subspaces and its properties Linear independence, basis, invariance of basis size, dimension of a vector space. Unit II : Ordinary Differential equations 37 First order exact differential equations. Integrating factors, rules to find and integrating factor. First order higher degree equations solvable for 71 x,y,p=dy/dx. Methods for solving higher-order differential equations. Basic theory of linear differential equations, Wronskian, and its properties. Solving an differential equation by reducing its order. Linear homogenous equations with constant coefficients. Linear non-homogenous equations. The method of variation of parameters, The Cauchy-Euler equation. Simultaneous differential equations, total differential equations. Applications of differential equations: the vibrations of a mass on a spring, mixture problem, free damped motion, forced motion, resonance phenomena, electric circuit problem, mechanics of simultaneous differential equations. Unit III : Partial Differential Equations 15 Order and degree of partial differential equations. Concept of linear and non-linear partial differential equations. Formation of first order partial differential equations. Linear partial differential equation of first order, Lagrange’s method, Charpit’s method. Classification of second order partial differential equations into elliptic, parabolic and hyperbolic through illustrations only. Applications to Traffic Flow. Recommended Books 1. Joseph A Gallian: Contemporary Abstract Algebra, fourth edition, Narosa, 1999. 2. George E Andrews: Number Theory, Hindustan Publishing Corporation. 1984 (Only sections 1-3 of chapter 12) 3. Shepley L. Ross: Differential equations, Third edition, John Wiley and Sons, 1984 4. I. Sneddon: Elements of partial differential equations, McGraw-Hill, International Edition, 1967. 72 BOTANY AND ZOOLOGY (LIFE SCIENCES) LS 201 BIODIVERSITY I : PLANTS Biodiversity has been referred to as “The planet Earth’s most valuable resource”. Understanding biodiversity requires a proper analysis of different organisms for their correct identification, proper naming and scientific classification. Information on the relationship amongst species is essential for evaluation biodiversity. This paper provides an evolutionary sequence in studying Biodiversity with reference to the plant Kingdom. It cover all groups of organisms traditionally studied by botanists, and emphasizes the importance of taxonomy in understanding Plant Diversity. Unit I Diversity in Nature Three domain classification (Karl Woelse); Understanding diversity from and evolutionary perspective from prokaryotes (bacteria cyano bacteria) to higher plants (angiosperms). Unit II Relevance of Plant Diversity The importance of plants in human life. Unit III Classification Characterization as the basis of classification. Introduction to taxonomic hierarchy (Kingdom, Division, Class, Order, Family, Genus, Species) and identification; Nomenclature. Artificial, Natural and Phylogenetic systems with special emphasis on Bentham & Hooker’s system and Takhtajan’s system. Introduction to Modern methods in plant taxonomy. Unit IV Viruses and Becteria A general account of structure, reproduction and types Diversity in Cyanobacteria, nitrogen fixation. Study of Nostoc. Unit V Algae A general account with stress on the significant characters and importance of the algae. Study of vegetative and reproductive structure of Volvox, Oedogonium, Vaucheria, Ectocarpus and Polysiphonia. 73 Unit VI Fungi An account of the general characters and the basic criteria used in fungal taxonomy. Ainsworth’s classification. Study of vegetative and reproductive structures of Rhizopus, Penicillium, Albugo, Puccinia and Agaricus. A General account of the Lichens. Unit VII Archegoniatae An introduction to the Archegoniate with emphasis on general characters and adaptation to land habit. Concept of apogamy and apospory; experimental studies in Bryophytes and Pteridophytes. Characteristic features and classification of Bryophytes and Pteridophytes. Study of vegetative and reproductive structures of Marchantia, Funaria, Selaginella, Equisetum and Pteris. Unit VIII Gymnosperms Distribution and important characters of Gymnosperms Vegetative and reproductive structures in different groups giving examples from Cycas, Pinus, Ephedra and Gingko. Outline of classification and economic importance. Unit IX Angiosperms General account, with emphasis on important characters. Diversity in form, structure and function. Suggested Readings Moore, R., Clarke, W.D., and Vodopich D. S. 1998. Botany (2nd edition)- McGraw-Hill, New York. Raven, P.H., Evert, K.F., and Eichhorn, S.E. 1999. Biology of Plants (5th edition). W.H. Freeman and Co. Worth Publishers, New York. Raven, P. H., Johnson, G.B., Losos, J.B., and Singer, S.R. 2005. Biology. Tata Mc Graw Hill, New Delhi. Bold, H.C., Alexopoulos, C., and Delevoras, T. 1980. Morphology of Plants and Fungi (4th edition). Harper and Row. New York. Alexopoulos, C. J., C. W. Mims and Blackwell. 1996. Introductory Mycology, 4th ed., John Wiley and Sons Inc. 74 Bhatnagar, S.P. & Moitra, A. 1996 Gymnosperms. New Age Int. Publ. House. New Delhi. Gurcharan Singh, 2004. Plant Systematics – Theory and Practice (2nd Ed.) Oxford & IBH Publishing Co. Pvt. Ltd. New Delhi. Srivastava, Sheela and Srivastava, P.S. 2004 Understanding Becteria Springer Verlag, Germany/Kluwer Acad., Netherlands. Foster, A.S. & Gifford, E.M. (1959). Comparative Morphology of Vascular Plants, Freeman, San Francisco. 75 LS 202 BIODIVERSITY II : ANIMALS Knowledge of animal diversity has an immense potential and utility, integration in modern scientific fields. Contemporary study of animal diversity cannot be carried out just in terms of their structure and functions; these have rather to be projected as a tool in understanding varied complexities of biological organization in order to find appropriate answers to unresolved issues. The present syllabus provides a strong and comprehensive base for animal diversity studies with this perspective. Unit I Classification General characteristics and outline classification of different animal groups (up to classes for Non-Chordates and up to orders for Chordates). Unit II Protista Locomotion, Reproduction, Economic importance of Protozoans. Unit III Porifera Skeleton, Canal System. Unit IV Cnidaria Metagenesis, Polymorphism, Corals and Coral reefs. Unit V Helminthes Parasitic adaptations and evolution of Parasitism. Unit VI Annelida Coelom, Metamerism, Excretion, Modes of Life in Polychaetes. Unit VII Arthropoda Vision, Respiration, Crustacean Larvae. Unit VIII Mollusca Torsion and Detorsion, Shell, Respiration. Unit IX Echinodermata Water Vascular system, Larval forms. Unit X Protochordata Salient features, affinities. 76 Unit XI Pisces Respiration, Osmoregulation, Migration of Fishes. Unit XII Amphibia Respiration, Parental care. Unit XIII Reptilia (The first Amniotes) Terrestrial Adaptation, Biting Mechanism in snake. Unit XIV Aves Respiration, Flight, Endothermy. Unit XV Mammalia Integument, Dentition, Evolution of Man. Suggested Readings Barnes, R.D. (1992). Invertebrate Zoology. Saunders College Publishers, USA. Campbell & Reece (2005). Biology, Pearson Education, (Singapore) Pvt. Ltd. Miller, S.A. and Harley, J.B. (2002). Zoology. Tata McGraw Hill Publishing Company, New Delhi. Kardong, K. V. (2002). Vertebrates Comparative Anatomy. Function and Evolution. Tata McGraw Hill Publishing Company. New Delhi. Raven, P. H. and Johnson, G. B. (2004). Biology, 6th edition, Tata McGraw Hill Publications. New Delhi. 77 LS 203 CELL BIOLOGY, BIOCHEMISTRY AND IMMUNOLOGY After biology course in school and foundation course in first year, the present course in cell biology, biochemistry and immunology is a logical sequel in progression and furtherance of knowledge in life science. Cell, the basic functional unit of life, desirably should be studied with emphasis on structure-function correlation. To facilitate this, essentials of biochemistry are an integral part of this paper. Immunology has been included as part of this course to learn about the dynamics of defense mechanisms the nature has provided to the cell. Unit I The Cell A brief introduction, cell theory, cell cycle and its regulation. Unit II Tools and Techniques Phase contrast, Fluorescence and Confocal microscopy, SEM, TEM. Cell fractionation. Chromatography: Paper and TLC. Electrophoresis. Use of radioisotopes: Autoradiography. Spectrophotometry. X-ray diffraction. Unit III Cell and cell membrane Cell wall: chemical components, structure and functions. Cell membrane: Models of cell membrane, transport mechanisms across cell membrane, plasmodesmata and junctions. Extracellular matrix of animal cells. Unit IV Cell organelles Mitochondria: structure and function, Racker’s Experiment. Chloroplasts: structure and function, thylakoid membrane Structure. Nucleus: structure and function, nuclear pore complex, nucleoius and its functions. Ribosomes: structure and function in eukaryotic and prokaryotic cell. ER, Golgi apparatus, microbodies, lysosomes and peroxisomes. Unit V Cytoskleton Microtubules: structure and function. Structure of cilia and flagella. Microfilaments. Unit VI Biomolecules Carbohydrates: Structure and functional significance of mono78 di-and polysaccharides. Lipids: structure, nomenclature, and functional significance of fatty acids, triglycerides, phospholipids, glycolipids and steroids, lipid peroxidation and role of antioxidants. Amino acids and Proteins: structure and general properties, role of chaperones in protein conformationy physiologically important peptides and proteins. Unit VII Metabolism Carbohydrate metabolism: glycolysis, citric acid cycle, pentose phosphate pathway, gluconeosenesis. Lipid metabolism: beta oxidation of fatty acids, ketogenesis. Protein metabolism: Overview of protein degradation, catabolism of amino acids transamination, oxidative deamination, blood transport of amino nitrogen, Fate of glycogenic and ketogenic amino acids. Biosynthesis of urea. Intermediary metabolism: Inter-relationships of carbohydrate, lipid and protein metabolism. Unit VIII Enzymes Nomenclature, classification, kinetics, mechanisms of action, inhibition. Unit IX Immunology Overview of immune system: innate, acquired immunity. Generation of immunogenicity, recognition of antigens, properties of B-cell and T-cell epitopes, antigen-antibody interactions. Immune effector mechanisms: Cytokines, complement system, hypersensitive reactions. Immune system in health and disease: vaccines, autoimmunity, AIDS, diagnostic tools. Suggested Readings Lehninger, A. L. Nelson, D. K. and Cox, M. M. (1993). Principles of Biochemistry, CBS Publishers and Distributors, New Delhi. Roitt, I.M. Essential Immunology. (2001). Blackwell Scientific Publications, New York. Sheeler, P. and D. E. Bianchi. (1987). Cell and Molecular Biology. John Wiley & Sons, New York. De Robertis, E. D. P. and De Robertis, E. M. F. Jr. (2002). Cell and Molecular Biology, Lipponcott Williams and Wilkins, USA. Richard, A.G. Kindt, T.J., Osborne, B.A. and Kuby, J. (2003). Immunology, W. H. Freeman and Co. New York. 79 LS 204 GENETICS, GENOMICS AND MOLECULAR BIOLOGY This course is designed for those students who have studied a general biology at first year level of B.Sc. Life Science. An attempt has been made to cover most aspects of genetics and its peripheral areas, which an undergraduate student must know. With the advent of recombinant DNA technology, the science of genetics has crossed a major milestone. The DNA sequences of a number of organisms including humans have already been worked out. This represents a major advancement and a new branch of genetics called genomics, is developing rapidly. Moreover, recent developments in molecular biology and biotechnology have impacted heavily almost all disciplines of biological sciences. The present syllabus has been drafted, keeping in mind the importance of classical genetics and molecular biology and significance of recent development keeping human perspective in mind. Unit I Heredity Mendel’s Laws of inheritance, Gene interactions: allelic and nonallelic, modified dihybrid ratios, complementary genes, epistasis, additive, inhibitory, lethal genes, pleiotropy, polygenic inheritance, cytoplasmic inheritance. Unit II Genetic material and its organization Chromosome morphology, karyotype and ideogram, Special types of chromosomes. Salivary gland chromosome, lampbrush chromosome. DNA/RNA as genetic material, nature of genetic material, Watson & Crick’s model, A, B and Z forms of DNA, chromatin organisation and packaging in eukaryotic chromosomes. Unit III Variation in Chromosome number and structure Euploidy, polyploidy, aneuploidy in plants and animals. Methylation and gene silencing. Down’s syndrome, Turner’s syndrome and Kleinfelter’s syndrome, Chromosomal aberrations deletion, duplication, inversion and translocation. 80 Unit IV Linkage and Crossing over Linkage, frequency of recombination and crossing over, cytological basis of crossing over; Sex determination and sexlinked inheritance. Unit V Mutation Types of mutation, mutagens — role of mutations in plant and animal improvements and in evolution. Unit VI Genomics Genome diversity and phylogeny, genetical and physical maps, genome wide sequence, bacterial, plant, animal and human genome (size and special features), introduction to functional genomics. Unit VII DNA replication in pro- and eukaryotes Gene concept, mechanisms of DNA replication, inhibitors of DNA replication. Unit VIII Transfer of genetic information in pro- and eukaryotes Transcription — types and structure of RNA, role of polymerase, initiation, elongation and termination of transcription, posttranscriptional modifications and inhibitors; splicing mechanisms. Translation-genetic code-features and deciphering of genetic code, inhibitors of protein synthesis. Unit IX Regulation of gene expression Prokaryotes inducible and repressible systems, positive and negative controls, DNA methylation. In eukaryotes: Tissuespecific and developmental stage specific expression of genes, gene amplification, puffing in polytene chromosomes. Unit X Molecular basis of recombination Holliday model, role of rec genes in genetic recombination. 81 Unit XI Cell-signaling and Programmed cell death (Apoptosis) Modes — endocrine, paracrine and autocrine signaling, signal transduction pathway of steroids and peptide hormones. Mechanisms of apoptosis, Role of apoptosis in human diseases. Unit XII Oncogenes and cancer Types of cancers — sarcomas, carcinomas, leukemias and lymphomas. Oncogenes, tumor suppressor genes. Suggested Readings Hartl, D. L. and E. W. Jones. 1998. Genetics: Principles and Analysis. Jones and Bartlett, USA. Hartwell, L. H. Hood, L., Goldberg, m.l., Reynolds, A. E. Silver, L.M., and Veres, R. C. 2004. Genetics — from genes to genomes (Second Edition). Mc Graw Hill, USA. Lewis, R. 1999. Human Genetics: Concepts and Applications. (3rd Edition) McGraw Hill, Dubuque, lA. Russel, P.J. 1998, Genetics. The Benjamin/Cummings Publishing Co. Inc., USA. Snustad, D.P. and M.J. Simmons. 2000. Principles of Genetics, 2nd ed. John Wiley and Sons, New York. Stern, C. 1973 Principles of Human Genetics. W. H. Freeman, San Francisco. Strickberger, M. W. 1985. Genetics. Collier MacMillan, Canada. 82 LS 205 LAB Bio Diversity I : Plants Paper I 1. Viruses: EM of TMV and Bacteriophage, study specimens of virus infected plants (any two). 2. Bacteria: Types through permanent slides/ photographs, specimens of infected plants (any tow). Nostoc 3. Algae: Mount material of (a) Volvox, (b) Oedogonium, (c) Vaucheria, (d) Polysiphonia, and (e) Ectocarpus to study vegetative and observe reproductive structures. 4. Fungi: Mount material to study thallus and reproductive structures in (a) Rhizopus, and (b) Penicillium. Observe specimens and permanent slides to study (a) Albugo, (b) Puccinia, (c) Agaricus. Lichen morphology. 5. Bryophytes: Study of (a) Marchantia from specimen and permanent slides only, (b) Funaria: detailed study – w.m. rhizoids, leaf, operculum, peristome, spores, permanent slides of archegonia, antheridia, and capsule. 6. Pteridophytes: Study (a) Selaginella, (b) Equisetum: from specimens and permanent slides only, and (c) Pteris – detailed study of T. S. of rachis, V. S. of sporophyll, W. M. of sporangium through preparations and permanent slides. 7. Gymnosperms: Study of Cycas and Pinus from specimens and permanent slides only. 8. Angiosperms: Taxonomic study of characters of one plant from each of the following families: (a) Brassicaceae, (b) Malvaceae, (c) Solanaceae, (d) Lamiaceae, (e) Asteracea, (f) Liliaceae. Classification according to the system of Bentham and Hooker. 83 9. Study of morphological variations/modifications of root — through preparation/permanent slides (tap root and adventitious root-tuberous, fasciculate, prop, stilt), stem (tuber, bulb, rhizome, runner, corm, cladode, phylloclade) and leaf (simple, compound — pinnate, and palmate, phyllode, tendril). Biodiversity II: Animals Non Chordata 1. Study of following specimen: Radiolaria/ Foraminiferan ooze, Euglena, Noctiluca, Paramecium, Leucosolenia, Sycon, Spongilla, Physalia, Tubipora, Aurelia, Metridium, Alcyonium Taenia, Ascaris, Nereis, Aphrodite, Leech, Bonellia, Peripatus, Limulus, Spider, Hermitcrab, Balanus, Daphnia, Millipede, Centipede, Beetle, Dragonfly, Bedbug, Butterfly, Chiton, Dentalium, Aplysia, Mytilus, Octopus, Nautilus, Asterias, Cucumaria, Echinus and Antedon. 2. Study of Permanent Slides: - Cross section of Sycon, Sea anemone and Ascaris. - T. S. of Earthworm passing through pharynx, gizzard, and typhlosolar intestine. - T. S. of arm of Star fish. Bipinnaria and Pluteus larva. - Trochobhore. 3. Dissections Digestive and nervous system of Earthworm, and Cockroach. 4. Temporary mounts – Septal & pharyngeal nephridia and ovary of earthworm. – Mouthparts and salivary apparatus of cockroach. Chordata 5. Study of following specimens Balanoglossus, Herdmania, Amphioxus, Petromyzon, Pristis, Electricray, Hippocampus, Clarias, Gambusia, Labeo, Icthyophis/ Uraeotyphlus, Salamander, Rhacophorus, Chamaeleon, Draco, 84 Uromastix, Anguis, Naja, Python, Viper, model of Archaeopteryx, 3 common birds-(Crow, duck, Owl), Squirrel and Bat. 6. Study of following permanent slides – Section of Amphioxus through pharynx gonads, intestine and caudal region. 7. Skeleton: Rabbit (disarticulated). 8. Dissections Afferent branchial system and cranial nerves (V, VII, IX X) of Scoliodon/Mystus. – Dissection of Rat: arterial, venous system and urinogenital system. 9. Temporary mount of following – Unstained mounts of Placoid, Cycloid and Ctenoid scales. 85 LS. 206 LAB Paper III–Cell Biochemistry & Immunology 1. Preparation: Squamous epithelium, epidermal peel of onion, Rhoeo leaf. 2. Study of the following techniques through photograph: Microscopy– Phase contrast and florescent, Electron Microscope-Scanning and Transmission: freeze fracture (membrane) technique. 3. Study of electron micrograph of prokaryotic and eukaryotic cell, chloroplast, mitochondria, Golgi apparatus, lysosome, endoplasmic reticulum (SER, RER), microtubules. 4. Cytochemical demonstration of Nucleic acids, proteins and polysaccharides (from permanent slides). 5. Temporary squash preparation to study meiosis (grasshopper testis/ Onion flower buds). 6. Demonstration of dialysis (glucose and starch). Study of plasmolysis and deplasmolysis using red onion peel/Rhoes. 7. Separation and identification of aminoacids by paper chromatography. 8. Study of effect of temperature, organic solvent on semi permeable membranes using beet root. 9. Measurement of cell size in epidermal peel by using stage and ocular micrometer. 10. Study of effect of temperature, pH and heavy metals on the action of salivary amylase. 11. Demonstration of primary (Bone marrow & Thymus ) and secondary immune organs (Spleen, Lymph nodes) in Rat. 12. Isolation, staining and counting of mononuclear cells from peripheral blood. 86 13. Determination of ABO Blood groups and Rh-factor. 14. Double simple immuno-diffusion test (Ouchterlony method). Paper IV – Genetics, Genomics & Molecular Biology 1. Study of gene interaction/ deviations from the Mendelian ratios using seed samples in the ratios of 9:7, 9:4:3, 13:3, 9:6:1, 15:1 and 12:3:1. 2. To study through photographs of the karyotype of diploid and polyploid of the same genus; and aneuploids (Down’s, Turner’s and Klinefelter) syndrome through photographs. 3. Preparation of the karyotype and idiogram from the given photograph of somatic metaphase chromosomes (Vicia/ Phlox/ Allium and Human). 4. Study of the organization of DNA in the eukaryotic chromosomes (through illustration). 5. Study of salivary gland and lampbrush chromosomes, laggards, bridges, multivalents and translocation ring. 6. Study of banding patterns (Q, C, G) through photograph. 7. To study sex chromosomes of Melandrium/ Coccinia (Permanent slide/photographs). 8. Temporary preparation of Barr bodies. 9. Study of inherited characters in human: Colour blindness and PTC test. 10. Isolation of DNA from cauliflower by spooling method. 87 COMPUTER SCIENCE CS 201 PROGRAMMING AND DATA STRUCTURES (3 Lectures per Week) 3 Hours, 100 Marks Fundamentals of Object Oriented Programming Primitive data types, abstraction and encapsulation objects, classesattributes and methods, input-output, control flow: sequence, selection and repetition, constructors, inheritance, reuse and polymorphism, exception handling mechanisms, organizing large programs. Date Structures Sorting and searching, stacks, queues, linked lists, binary trees, implementation using OOP language, basics of complexity of algorithms. References 1. Bjarne Stroustrup, The C++ Programming Language, Addison-Wesley. 2. Stanley B. Lippman, Josée Lajoie, C++ Primer, Pearson Education. 3. Herbert Schildt, C++. The Complete Reference, Tata McGraw Hill. 4. Mark Allen Weiss, Data Structures and Problem solving using C++, Addison-Wesley. 5. Robert L. Kruse, Alex Ryba, Data Structures and Program Design in c++ Prentice Hall of India. 6. Yedidyah Langsam. Moshe J. Augenstein, Aaron M. Tenenbaum. Data Structures using C and C++, Prentice Hall of India. 88 CS 202 COMPUTER SYSTEM ARCHITECTURE (3 Lectures per Week) 3 Hours, 100 Marks Introduction: Logic gates, boolean algebra, combinational circuits, circuit simplification flip-flops and sequential circuits, decoders, multiplexors, registers, shift registers, counters, memory units. Data Representation: Number systems, complements, fixed and floating-point representation, character representation. Computer Arithmetic : Addition, subtraction, magnitude comparison, multiplication, and division algorithms for integers. Basic Computer Organization and Design: Computer registers, bus system, instruction set, timing and control, instruction cycle, memory reference, input-output and interrupt, design of basic computer. Programming the Basic Computer: Instruction formats, addressing modes, instruction codes, machine language, assembly language, input output programming. Central Processing Unit: Register organization, register transfer and micro-operations—register transfer language, arithmetic and logical microoperations, stack organization, micro programmed control. Input-output Organization: Peripheral devices, I/O interface, asynchronous data transfer, priority interrupt, direct memory access, I/O processor, serial communication. Memory Organization: Main memory, auxiliary memory, associative memory, cache memory, virtual memory. References 1. M. Morris Mano, Computer System Architecture, Prentice Hall of India. 2. William Stallings, Computer Organization and Architecture, Prentice Hall of India. 89 CS 203 LAB (BASED ON CS. 201 and CS. 202) (4 Periods / Weed - 4 Hours, 100 Marks) 90 STATISTICS ST 201 STATISTICAL METHODS AND PROBABILITY THEORY ( 75 Lectures) Statistical Methods: Concepts of a statistical population and sample from a population, quantitative and qualitative data, nominal, ordinal and time series data, discrete and continuous data, Presentation of data by tables and by diagrams, frequency distributions for continuous and discrete data, graphical representation of a frequency distribution by histogram and frequency polygon, cumulative frequency distributions (inclusive and exclusive methods). Measures of location (or central tendency) and dispersion, moments, measures of skewness and kurtosis, absolute moments. Bivariate data: Scatter diagram, principle of least squares and fitting of polynomial and Exponential curves, Correlation and Regression, Karl Pearson coefficient of correlation, Lines of regression, Spearman’s rank correlation coefficient, multiple and partial correlations (for 3 variates only). Probability Theory: Random experiment, sample point and sample space, event, algebra of events, Definition of Probability—classical, relative frequency and axiomatic approaches to probability, Theorems on probability, conditional probability, and independent events. Random Variables: Discrete and continuous random variables, p.m.f., p.d.f. and c.d.f., illustrations of random variables and its properties, expectation of random variable and its properties, Moment generating function, Transformation of variates in univariate case, Bivariate distributions, Marginal and conditional distributions. Distributions: Point (or degenerate), Binomial, Poisson, Geometric, Negative Binomial, Normal, Uniform, Exponential distributions. Bivariate Normal distribution and related marginal and conditional distributions, Concept of multinomial distribution. 91 Chebyshev’s inequality, WLLN, SLLN (Statement only), applications, central limit theorem (C. L. T. ) for i.i.d. variates and applications of C.L.T.. Suggested Readings 1. Freund J. E. (2001): Mathematical Statistics, Prentice Hall of India. 2. Goon, A. M,. Gupta M. K. and Dasgupta, B. (1991): Fundamentals of Statistics, Vol. I, World Press, Calcutta. 3. Hogg, R. V. and Craig, A. (1999): Introduction to Mathematical Statistics, Prentice Hall. 4. Mood, A. M., Graybill, F. A. and Boes, D. C. (2001): Introduction to the Theory of Statistics, Tata McGraw-Hill Pub. Co. Ltd. 5. Ross, S.M. (2003): Introduction to Probability Models, Academic Press. 92 ST 202 APPLIED STATISTICS (75 Lectures) Economic Statistics: Time Series Analysis-economic time series, different components, illustrations, additive and multiplicative models, determination of trend, growth curves, analysis of seasonal fluctuations, variate difference methods. Periodogram analysis, Autocorrelation, Correlogram for moving average and AR (1) processes. Index Numbers— Criteria for a good index number, Different types of index numbers, Construction of index number of prices and quantities, Paasche’s. Laspeyre’s and Fisher’s Ideal index numbers, Time reversal, Factor reversal and Circular tests, Construction of index number of cost of living and industrial production. Uses and limitations of index numbers. Statistical Quality control: Importance of statistical methods in industrial research and practice determination of tolerance limits, general theory of control charts, Process and product control, causes of variation in quality control limits, summary of out of control criteria, charts for attributes— p-chart, np-chart, c-chart, charts for variables- X , R and s charts, Principles of acceptance sampling, problem of lot acceptance, producer’s and consumer’s risks, single and double sampling plans and their OC and ASN functions, concepts of AQL, LTPD, AOQL, ATI functions, Dodge and Romig tables. Demographic Methods: Sources of demographic data—census, register, adhoc surveys, hospital records, demographic profiles of Indian Census, questionnaire, errors in these data and their adjustment. Measurement of Mortality, CDR, SDR (with respect to age and sex), IMR, morbidity rate, standardised death rate, complete life table, its main features and uses. Measurement of fertility and reproduction - CBR, General, specific and total fertility rates, GRR, NRR, Vital index, graduation of mortality rates by Gompertz and Makeham’s Law, Logistic Curve, its fitting by the method of three selected points, pearl-Reed’s method, Rhode’s method and its uses in population projection. 93 Suggested Readings 1. Croxton, F. E. and Cowden, D. J. (1969): Applied General Statistics, Prentice Hall of India. 2. Goon, A. M., Gupta, M. K. and Dasgupta, B. (1991): Fundamentals of Statistics, Vol. II, World Press, Calcutta. 3. Kendall, M. G. and Stuart, A. (1977): The Advanced Theory of Statistics, Vol. III, Macmillan Publishing Co. 4. Montgomery, D. C. (2005): Introduction to Statistical Quality Control, Fifth Education, John Wiley & Sons. 5. Mukhopadhyay, P. (1999): Applied Statistics, Books and Allied (P) Ltd., Kolkata. 94 ST 203 STATISTICS LABORATORY - I Handling of problems based on Statistical methods, Economic Statistics, Statistical Quality Control and Demographic methods as covered under ST. 201 and ST. 202; the practicals to be carried out on computer by developing programs via Python/C Language. 95 OPERATIONAL RESEARCH OR 201 OPTIMIZATION (Three Lectures plus one tutorial per week) Total Marks : 150 Internal Assessment : 38 marks Examination : 112 marks Duration : 3 Hours Origin of Operational Research, Definition, Meaning and Development of Operational Research, Different Phases of an Operational Research Study, Scope and Limitations of Operational Research, Mathematical Modelling of Real Life Problems as Linear Programming. Solution of a System of Linear Equations, Concept of Basis, Basic Feasible Solution, Convex Sets and Extreme Points. Theory of Simplex Method, M-Charnes Simplex Methods, Two-Phase Simplex Method. Degeneracy in Linear Programming, Duality in linear programming, Economic Interpretation of Duality, Sensitivity Analysis in Linear Programming, Transportation Problem, Assignment Problem, Linear Integer Programming. Suggested Readings 1. K. Chandrasekhra Rao and Shanti Lata Mishra : Operations Research, Narosa Publishing House Pvt. Ltd., 2005. 2. Hadley, G. Linear Programming, Narosa Publishing House, 2002. 3. Hamdy, A. Taha : Operations Research: An Introduction, 6th Ed., Prentice Hall, 1996. 96 OR 202 INVENTORY MANAGEMENT AND QUEUEING THEORY (Three Lectures plus one tutorial per week) Total Marks : 150 Internal Assessment : 38 marks Examination : 112 marks Duration : 3 Hours (a) Inventory Management: Introductory Concepts and Problems in Inventory Management, Selective Inventory Control (ABC Analysis), Different Costs in Inventory Control and Method of their Estimation. General Inventory Models for Demand Known with Certainty, With and Without Lead Time and With and Without Shortages. Inventory Models with Price Breaks (All-Unit and Incremental). Multi Item Model with Constraints. Production Scheduling Problem. Single Period Stochastic Inventory Models. (b) Queueing Theory: General Concepts of Queueing Systems, Measures of Performance, Arrival and Services Processes, Deterministic Queueing Model, Single Server and Multiserver Models (M/M/1 M/M/c), Generalized Birth—Date Queueing System and its Particular Cases, Erlang Distribution, M/Ek/1 and Ek/M/1 Queueing Models (Steady State solutions Only). Application of Simple Queueing Decision Models. Suggested Readings 1. Donal Waters: Inventory Control & Management, John Wiley & sons, 2003. 2. D. Gross and Harris, C. M.: Fundamentals of Queueing Theory, John Wiley, 2004. 3. Hamdy, A.: Taha Operations Research: an Introduction, 6th Ed., Prentice Hall, 1996. 4. Hiller, F. S. and Liberman, G. J.: Introduction to Operations research, 7th Ed., McGraw Hill, 2001. 97 ELECTRONICS EL 201 ANALOG AND DIGITAL CIRCUITS (Total Lectures: 70) Total Marks : 100 Network Analysis (14 L) Current and voltage Sources. Introduction to Network Analysis (KV L and KCL), Mesh and Node analysis, Conversion between T and p sections. Thevenin’s, Norton’s, Maximum Power, Superposition and Reciprocity Theorems. Two-port networks (Z, Y, ABCD and h-parameters) Low pass, High pass and Band pass filters (RC) Diode Circuits (5 L) Diode as a circuit element, positive, negative and biased clipper circuits, clamping circuits. Analysis of rectifier circuits, ripple factor and power conversion efficiency. Reduction of ripple factor by C and L filters. Transistor Circuits (12 L) Review of BJT characteristics (CB, CE and CC), Transistor Hybrid Model, quiescent point, biasing (fixed and self) of a transistor circuit. Small signal analysis of the CE amplifier. Derivation of voltage and current gains, input impedance, output impedance and frequency response. Qualitative comparison of transistor amplifier circuits in CB, CE and CC configurations. Class A, Class B and Class C amplifiers. Analysis of Class B push-pull amplifiers (efficiency, power dissipation). Number System (4 L) Binary number system, binary to decimal conversion, decimal to binary conversion, signed binary numbers (sign ,magnitude, I’s complement and 2’s complement representations), binary arithmetic (addition, subtraction, 98 multiplication, division), 2’s complement arithmetic, octal and Hexadecimal Number system, Codes (straight binary code, BCD Code and Gray Code). Logic Gates (2 L) Basic digital Gates (OR, AND, NOT, NAND, NOR, XOR, XNOR), positive and negative logic, Boolean algebra theorems, Examples of IC Gates. Digital Logic Families (5 L) Various logic families (Bipolar: RTL, DTL, TTL and ECL; Unipolar: PMOS, NMOS, CMOS) and a comparison their characteristics (basic gates, fan-out, power dissipation, noise immunity, propagation delay, clock-rate, number of functions). Combinational Logic Design (10 L) Standard representation of logical functions (SOP, POS), Karnaugh map representation and simplification (limited to four variables). Arithmetic Circuits (half and full adders, half and full subtractors), BCD adder. Demultiplexers / Decoders, Multiplexers, Encoders, Code converters (BCD-to Binary and Binary to BCD converters). Sequential Logic Design (12 L) Sequential systems, I-bit memory, Latch, S-R Flip-Flop, J-K Flip-Flop (Race-around Condition, Master-Slave), T and D Flip-Flops. Registers, Modes of operation (SISO, SIPO, PISO, PIPO), Shift Registers (4-bit). Ripple or Asynchronous Counters, Synchronous Counters, Up-Down counters, ring counter, decade counter. Memories (6 L) Volatile, non-volatile memories, ROM, PROM, EPROM, EEPROM, RAM (SRAM, DRAM), cache memory. 99 Suggested Readings 1. Nasar S.A., Electric Circuits, Schaum’s Outline Series, Tata McGraw- Hill, 2005. 2. Malvino A.P., Electronic Principles, Tata McGraw-Hill, 2005. 3. Ryder J.D., Networks, Lines and Fields, Prentice Hall of India, 2004. 4. Jain R.P., Modern Digital Electronics, Tata McGraw-Hill, 2003. 5. Bali S.P., Solved Problems in Digital Electronics, Sigma Series, Tata McGraw-Hill, 2005. 6. Mano M.M., Digital Design, Pearson Education Asia, 2002. 7. Floyd T.L., Digital Fundamentals, Pearson Education Asia, 2004. 100 EL 202 SEMICONDUCTOR DEVICES AND FABRICATION (Total Lectures: 70) Total Marks : 100 Properties of Semiconductors (14 L) Energy band in solids, Kronig Penney model, band diagram of semiconductor, metal and insulator, Concept of Fermi level, Direct and indirect band-gap semiconductors. Charge carriers in semiconductors — electrons and holes, concept of effective mass, intrinsic semiconductor, concept of doping, extrinsic semiconductor. Carrier transport phenomenon: conductivity, mobility and sheet resistance, effect of temperature on mobility, Hall effect. Junction Diodes and Bipolar Transistors (16 L) The PN junction, formation of depletion layer, space charge at a junction, qualitative description of current flow at a junction, derivation of electrostatic potential difference at thermal equilibrium, depletion width and depletion capacitance for abrupt junction, diode equation and dependence of I-V characteristics on temperature. Reverse bias breakdown (Zener and avalanche), Zener and avalanche diodes. Basic idea of varactor diode, tunnel diode, photo diode, solar cell, light emitting diode. PNP & NPN transistor, transistor action, energy band diagram of transistor in thermal equilibrium. Metal Semiconductor Contacts (6 L) Energy band diagram, Schottky Effect, rectifying and ohmic contacts. Field Effect Transistors (14 L) Construction and characteristics of Junction Field Effect Transistor (JFET) and Metal-Semiconductor Field Effect Transistor (MESFET). 101 Basic structure of a Metal-Oxide Semiconductor Field Effect transistor (MOSFET) and its characteristics (n, p-channel, enhancement and depletion modes). Semiconductor Fabrication Technology (20 L) Introduction to semiconductor technology. Basic fabrication steps: epitaxial growth, oxidation, photolithography, etching, diffusion, ion implantation, film deposition and metallisation. Process integration for Integrated Circuits, Diodes and transistors for monolithic circuits, integrated resistors, capacitors and inductors, monolithic circuit layout. Moore’s Law, Medium Scale Integration (MSl), Large Scale Integration (LSI), Very Large Scale Integration (VLSI), Ultra Large Scale Integration (ULSI). Giant Scale Integration (GSI). Suggested Readings 1. Sze S.M., Physics of Semiconductor Devices, John Wiley, 1999. 2. Millman J. and Halkias C.C., Integrated Electronics, Analog and Digital Circuits and Systems, Tata McGrraw-Hill, 2004. 3. Millman J. and Halkias C.C., Electronic Devices and Circuits, Tata McGraw-Hill, 2005. 4. Cathey J. J., Electronic Devices and Circuits, Schaum’s Outline Series, Tata McGraw-Hill, 2005. 5. May G.S. and Sze S.M., Fundamentals of Semiconductor Fabrication, John Wiley (WES Edition), 2004. 6. Cheruku D.R. and Krishna B.T., Electronic Devices and Circuits, Pearson Education Asia, 2005. 102 EL 203 ELECTRONICS LAB - I Total Marks : 100 Module-I Analog Electronics 1. Verification of Network Theorems: Thevenin’s, Maximum Power and Superposition (1) 2. T and p Networks (1) 3. h-parameters of CE configuration, design of CE Amplifier (2) 4. Operational amplifiers: clipper, clamper, integrator, differentiator (4) 5. Characteristics of SCR, DIAC, TRIAC (3). Module-II Digital Electronics 6. Verification of Gates: OR, AND, NOT, NAND, NOR, XOR and XNOR by use of NAND Gates of IC 7400 (1) 7. Arithmetic Circuits: Half and full adders and subtractors using NAND Gates (2) 8. Multiplexers and Demutiplexers: 4×1 MUX, 1 × 4 DMUX using NAND Gates (2) 9. Flip-Flops: Study of SR, D, JK, master slave flip-flops including clocked SR and D flip-flops (3) 10. Four bit shift register: SISO, PISO using Flip-Flops (1) 11. Counters: Study of up-down counter, divide by N circuit and decade counter (4). 103 INDUSTRIAL CHEMISTRY IC 201 INDUSTRIAL CHEMICALS AND ENVIRONMENT (Total Lectures : 75) Total Marks : 100 I. Chemical Technology Basic principles and calculations in industrial chemical processes. Heat transfer and mass transfer; mixing and agitation, crystallization, filtration, drying, grinding and sieving. Fundamental concepts and practical techniques for solving problems relating to equilibria stage processes. Distillation, solvent extraction, solid-liquid leaching and liquid-liquid extraction, separation by absorption and adsorption. An introduction into the scope of different types of equipment needed in chemical technology, including reactors, distillation columns, extruders, pumps, mills, emulgators. Scaling up operations in chemical industry. Introduction to clean technology. II. Industrial Gases and Inorganic Chemicals (a) Industrial Gases : Large scale production, uses, storage and hazards in handling of the following gases: oxygen, nitrogen, argon, neon, helium, hydrogen, acetylene, carbon monoxide, chlorine, fluorine, sulphur dioxide and phosgene. (b) Inorganic Chemicals: Manufacture, application, analysis and hazards in handling the following chemicals: fluorine, chlorine, bromine, iodine, hydrochloric acid, nitric acid, sulphuric acid, sulfamic acid, hydrazine, phosphoric acid, sodium carbonate and bicarbonate, caustic soda, common salt, bleaching powder, sodium thiosulphate, hydrogen peroxide, potash alum, chrome alum, potassium dichromate and potassium permanganate. III Industrial Metallurgy Preparation of metals (ferrous and nonferrous) and ultra pure metals for semiconductor technology. 104 IV. Silicate Industries (a) Glass: Glassy state and its properties, classification (silicate and non silicate glasses). Manufacture and processing of glass, composition and properties of the following types of glasses: Soda lime glass, lead glass, armoured glass, safety glass, borosilicate glass, fluorosilicate, coloured glass, photosensitive glass, glass fiber, coated glasses and fotoform. (b) Ceramics: Important clays and feldspar, ceramic, their types and manufacture. High technology ceramics and their applications, aero space composites, super conducting and semi conducting oxides, fullerenes carbon nanotubes and carbon fiber. (c) Cements : Classification of cement, ingredients and their role, Manufacture of cement and the setting process, quick setting cements. V. Environment (a) Air Pollution: Pollutants and their sources, pollution by SO2, CO2,CO, NOx, H2S and other foul smelling gases. Methods of estimation of CO, NOx, SOx and control procedures. Green House effect and Global warming, Ozone depletion by oxides of nitrogen, chlorofluorocarbons and Halons, removal of sulphur from coal. Control of particulates. (b) Water pollution and Water Quality Standards: Pollutants and their sources, Effluent treatment plants (primary, secondary and tertiary treatment). Industrial effluent from the following industries and their treatment: electroplating, textile, tannery, dairy, petroleum and petrochemicals, agro, fertilizer, etc.. Sludge disposal. Industrial waste management, incineration of waste. Water treatment and purification (reverse osmosis, electro dialysis, ion exchange). Water quality parameters for waste water, industrial water and domestic water. Suggested Readings 1. E. Stocchi, Industrial Chemistry, Vol-I, , Ellis Horwood Ltd. UK. 2. R. M. Felder, R. W. Rousseau, Elementary Principles of Chemical Processes, Wiley Publishers, New Delhi. 105 3. W. D. Kingery, H. K. Bowen, D. R. Uhlmann, Introduction to Ceramics, Wiley Publishers, New Delhi. 4. J. A. Kent, Riegel’s Handbook of Industrial Chemistry, CBS Publishers, New Delhi. 5. S. S. Dara, A Textbook of Engineering Chemistry, S. Chand & Company Ltd. New Delhi. 6. A. K. De, Environmental Chemistry, New Age International Pvt, Ltd, New Delhi. 7. S. M. Khopkar, Environmental Pollution Analysis, Wiley Eastern Ltd, New Delhi. 106 IC 202 FOSSIL FUELS AND FERMENTATION INDUSTRIES (Total Lectures: 75) Total Marks : 100 I. Fuel Chemistry Review of energy sources (renewable and non-renewable). Classification of fuels and their calorific value. (a) Coal: Uses of coal (fuel and non fuel ) In various industries, its composition, carbonization of coal, coal gas, producer gas and water gas—composition and uses. Fractionation of coal tar, uses of coal tar bases chemicals, requisites of a good metallurgical coke, Coal gasification (Hydro Gasification and Catalytic gasification), Coal liquefaction and Solvent Refining. (b) Petroleum and Petrochemical Industry: Composition of crude petroleum, Refining and different types of petroleum products and their applications. Fractional Distillation (Principle and process), Cracking (Thermal and catalytic cracking), Reforming Petroleum and non petroleum fuels (LPG, CNG, LNG, bio-gas, Fuels derived from biomass), fuel from waste, synthetic fuels (gaseous and liquids), clean fuels. Petrochemicals: Vinyl acetate, Propylene oxide, Isoprene, Butadiene, Styrene, Cumene, Toluene and its derivatives, Xylene, Naphthalene, Anthracene. (c) Lubricants: Classification of lubricants, lubricating oils (conducting and non-conducting) Solid and semisolid lubricants, synthetic lubricants. Properties of lubricants (viscosity index, cloud point, pore point) and their determination. II. Oils and Fats Classification of oils, fat splitting, distillation of completely miscible and non-miscible oils, hydrogenation of oils, Soap and Synthetic Detergent, Preparation of soap and detergent, different types of soap and their composition, surfactants, detergent binders and builders. 107 III. Cosmetics and Perfumes A general study including preparation and uses of the following: Hair dye, hair spray, Shampoo, Suntan lotions, face powder, lipistics, talcum powder, nail enamel, Creams (cold, vanishing and shaving creams), antiperspirants and artificial flavours. Essential oils and their importance in cosmetic industries with reference to Eugenol, Geraniol, sandalwood oil, eucalyptus, rose oil, ß-phenyl ethyl alcohol, Jasmone, Civetone, Muscone. IV. Catalysis General principles, description of catalysts, properties of catalysts, homogenous catalysis (catalytic steps and examples) and heterogenous catalysts (nature catalytic steps and examples) and their industrial applications, Deactivation or regeneration of catalysts. Phase transfer catalysts, application of zeolites as catalysts. Oxo- Process, Wacker Process and Monsanto Process. V. Fermentation Industries Aerobic and anaerobic fermentation. Production of (i) Ethyl alcohol and citric acid, (ii) Antibiotics Pencillin, Cephalosporin, Chloromycetin and Streptomycin, (iii) Lysine, Glutamic acid, Vitamine B2 Vitamine B12 and Vitamine C. Suggested Readings 1. O. P. Vermani, A. K. Narula, Industrial Chemistry, Galgotia Publications Pvt. Ltd., New Delhi. 2. S. C. Bhatia, Chemical Process Industries, Vol. I & II, CBS Publishers, New Delhi. 3. P. C. Jain, M. Jain, Engineering Chemistry, Dhanpat Rai & Sons, Delhi. 4. R. Gopalan, D. Venkappayya, S. Nagarajan, Engineering Chemistry, Vikas Publications, New Delhi. 5. B. K. Sharma, Engineering Chemistry, Goel Publishing House, Meerut. 6. Sukumar Maiti, Introduction to Petrochemicals, Oxford Publishing Co., New Delhi. 108 IC 203 INDUSTRIAL CHEMISTRY LAB - I Total Marks : 100 1. Percentage of available chlorine in bleaching powder. 2. Measurement of SO2 and NOx in air samples. 3. Separation of essential oils by steam distillation. 4. Analysis of oils and fats (iodine value, saponification value, acid value). 5. Analysis of the following in a water sample: temporary and permanent hardness, Total dissolved solids (TDS), PO4 3- , NO2 - NO3 - SO4 2 - CI- , BOD, COD, DO free chlorine. 6. Preparation of talcum powder. 7. Preparation of shampoo. 8. Preparation of enamels. 9. Preparation of hair remover. 10. Preparation of face cream. 11. Preparation of Aspirin and its analysis. 12. Preparation of nail polish and nail polish remover. 13. Separation of cations and anions using ion exchange resins. 14. Estimation of glucose in a food sample. 15. Determination of heavy metals in fly ash. 16. Extraction of natural colouring and flavouring agents from flowers and fruit. 17. Determination of alkali in water samples and soaps. 18. Testing of turmeric, milk and mustard oil for adulterants. 109 ANALYTICAL CHEMISTRY AC. 201 BASIC PRINCIPLES AND LABORATORY OPERATIONS (Total Lectures: 70) Total Marks : 100 I. Introduction to Analytical Chemistry Methods of analytical determination, methods of qualitative analysis, methods of quantitative analysis, selection of methods of analysis, role of instrumentation in analytical chemistry, various applications of analytical chemistry. II. Evaluation of Analytical Data Accuracy and precision, Methods for their expression, classification of errors, Detection and correction of determinate and indeterminate errors. The normal law of Distribution of indeterminate errors. III. Statistical Tests of Data The F test and the T test, rejection of data: The method of least squares, Propagation of errors in computation. Significant figures. IV. Sampling in Analytical Chemistry Theory of Sampling, Techniques of Sampling, Criteria for good sampling, Stratified sampling vs Random sampling. Transmission and storage of samples, Primary and secondary standards, various units for expressing quantitative results. E. G. Normality, Molarity, Molality, Formality, ppm. Ppb etc. V. Laboratory Operations Single pan analytical balance: (operation and theory of the balance, construction details, errors in weighing, care of an analytical balance) Description and use of common laboratory apparatus: (burettes, 110 chromatographic columns, chromatographic jars, desiccators, drying ovens, filter crucibles, meniscus readers, pH meters, pipettes, rubber policemen, separating funnels, spectrophotometers, volumetric flasks, weighing bottles, weighing paper) Laboratory notebook. Suggested Readings 1. S. M. Khopkar, Basic Concept of Analytical Chemistry, New Age International Publisher. 2. F. W. Fifeld and D. Kealy, Principles & Practice of Analytical Chemistry, Oxford, Blackwell Science. 3. D. A. Skoog, F. J. Holler and T. A. Nieman, Principles of Instrumental Analysis, Thomson Asia Pvt. Ltd. Singapore. 111 AC 202 QUANTITATIVE METHODS OF ANALYSIS (Total Lectures: 70) Total Marks : 100 A. Volumetric Method of Analysis Theory of Volumetric titration, concept of equivalence point and end point, Detection of end point, by visual indicator method and by instrumentation method, Theory of indicators. Classification of Titrations 1. Acid-Base Titration: (a) Strong Acid vs Strong Base (b) Strong Acid vs Weak Base (c) Weak Acid vs Weak Base (d) Strong Base vs Weak Acid Calculation of pH at the end point, choice of indicators 2. Redox Titrations Theory of redox titrations, choice of indicators, theory of redox indicators. (a) Ce4+ {(NH4) Ce (NO3)6} vs Fe2+(Mohr slat) with ferroin as indicator (b) KmnO4 vs Oxalic acid with KmnO4 as self indicator (c) Iodometric titratons, determination of available chlorine in bleaching powder. 3. Precipitation Titration Theory of precipitation, factors influencing solubility of precipitates, choice of indicators, adsorption indicators in 112 precipitation titrations. (a) AgNO3 vs Na2CrO4 – Mohr’s method (b) AgNO3 vs NH4SCN-Volhard’s method, Ferric alum as an indicator. B. Potentiometric Titrations Basic principles, various types of electrodes-calomel electrode, glass electrode, ion-selective electrodes, pH titrations, redox titrations (KMnO4/ K2CrO7 vs Mohr salt). C. Conductiometric Titrations: Basic principles, titration cunes of acid-base titrations and their interpretation, titration of mixture of acids (strong & weak) with base. D. pH-meter: Components of a pH-meter, Hydrogen ion and use of a pH meter, maintenance of pH-meter, applications of the data. E. Gravimetic Method of analysis Theory and principle of gravimetric analysis, classification of various methods in gravimetric analysis, optimum conditions for precipitation. (a) Analysis by co-precipitation method (b) Analysis by post precipitation method (c) Precipitation from bemogenous solution (d) Introduction of electro gravimetric method. Suggested Readings: 1. J. Mendham, R. C. Denney, J. D. Barner and M.J.K. Thomas, Vogel’s Textbook of Quantitative Chemical Analysis, Pearson Education, New Delhi. 2. F. W. Fifeld and D. Kealy, Principles & Practice of Analytical Chemistry, Oxford, Blackwell Science. 3. S. M. Khopakr, Basic Concept of Analytical Chemistry, New Age International Publishers. 113 AC 203 ANALYTICAL CHEMISTRY LAB - I Total Marks : 100 1. Caliberation of Laboratory Apparatus 2. Volumetric titrations (i) Acid-Base titration (ii) Precipitation titration (iii) Redox titration (iv) Complexometric titration (v) Determination of Hardness of water (vi) Determination of total dissolved solid (TDS) 3. Gravimetric estimation (i) By co-precipitation method (ii) By precipitation from homogenius solution 3. Analysis of soil (i) Determination of pH of soil (ii) Total soluble salt (iii) Estimation of Calcium, Magnesium and iron (iv) Carbonate and bicarbonate estimation. 114 ENVIRONMENTAL SCIENCE ES 201 CONCEPTS IN ECOLOGY (Total Lectures: 72) Total Marks : 100 Unit I : Introduction Scope and relevance of ecology Unit II : Factors in the environment Atmosphere, Soil, Water, Light, Temperature, Wind, Climate, Topography Optimal and limiting factors: Liebig law of the minimum, Shelford law of tolerance Unit III : Adaptations of organisms to the environment Ecological amplitude Water, salt, temperature — tolerance and avoidance Ecotypes Isolation, evolution, speciation Indicator species Unit IV : Interactions among organisms Competition Exploitation: Predation, Herbivory, Parasitism, Disease Mutualism Unit V : Population ecology Population growth and structure — growth, death, age structure, equilibrium Population regulation — abiotic factors, resource and inteference competition, niche concept Unit VI : Community ecology Community structure Community dynamics 115 Associations Ecological succession Ecotones Unit VII : Ecosystem ecology Diversity Structure and organization of ecosystems Flow of energy and nutrients Nutrient replenishment (Biogeochemical cycles) Unit VIII : Major ecosystems of the world Terrestrial ecosystems (biome types and distribution— forests, grasslands, desert) Aquatic ecosystems (freshwater, marine, estuaries, coral reefs, wetlands Agroecosystems Unit IX : Biogeography Phytogeography (principles, descriptive and interpretive, Age and Area hypothesis); Vegetation of India Zoogeography (Barriers to dispersal, Means of dispersal, Bathymetric and geologic distribution) Endemism Suggested Readings 1. Odum and Barett (2005). Fundamentals of Ecology. 5th edition, Thomsom Asia Pvt Ltd. 2. Ricklefs and Miller (2002) Ecology, 4th edition, Freeman and Company. 3. Kormandy, E.J. (2002). Concepts of Ecology. Prentice-Hall India and New Jersey. 4. Smith, R.L. (1996). Ecology and Field Biology. Harper Collins College Publications. 5. Begon, M., Harper, J. L. and Townsend, C. R. (1995). Ecology— Individual, Populations and Communities. Blackwell Scientific Publishers, Oxford. 116 ES 202 NATURAL RESOURCE MANAGEMENT (Total Lectures: 72) Total Marks : 100 Unit I : Biodiversity Microbial, plant, animal and habital diversity Relevance, evolutionary significance Biodiversity at local, national and global levels Measures and documentation (including traditional knowledge) Values — social, aesthetic and ethical Loss — threats, endangered and extinct species (case studies) Threats from introduced species — case studies Hot spots (special reference to India) Unit II : Management of biodiversity Landscape and habitat management Conservation — gene pool management (in situ, ex situ), germplasm banks, Biosphere reserves, National Parks, Wild Life Sanctuaries, Botanical gardens and Zoological parks-roles and mandates. Case studies — biodiversity parks, herbal gardens, butterfly parks, lichen and cryptogam collections, snake parks. Unit III : Fresh water resources Basic concepts— the basin, natural drainage Properties of fresh water—quality criteria, chemical composition, salinization Environmental influences on quality and quantity of surface and ground water— evapotranspiration, meterological phenomena, urbanization and industrialization Water resource management-rain water harvesting, catchment areas National Water Policy 117 Unit IV : Marine resources Properties of marine water — quality criteria, chemical composition environmental influences Mineral and biological resources Marine farming (fisheries, sea weeds) Unit V : Forest resources Forest dynamics, carbon and nutrient budgeting Use and over-exploitation, Deforestation Restoration programs Social and Agro forestry, Joint forest Management. Captive plantations— case studies Unit VI : Land resources Land use pattern, irrigation, fertilizer and pesticide related problems–case studies Rangeland management (includes impact of overgrazing) Minerals — resources and reserves Utilization and impact assessment of mining — case studies Restoration of degraded lands Unit VII : Energy resources Energy use scenario in India and different parts of the world Strategies for utilization of conventional and non-conventional energy sources — case studies Clean fuel technology Unit VIII : Sustainable utilization of resources Concept of sustainability Temporal and spatial dimensions Currencies for evaluation of sustainable development 118 Suggested Readings 1 Ramakrishnan, P. S. (2001). Ecology and Sustainable Development, National Book Trust, India. 2 Rogers, John, J. W. and P. Geoffrey Feiss (1998). People and Earth: Basics Issues on the Sustainability of Resources and Environment. Cambridge University Press. 3 Francis R: Ecology and Natural Resources. John Wiley and Sons, New York. 4 Sagreiya, K. P. (1994). Forests and Forestry. National Book Trust., New Delhi. 5 Miller, G. Tyler (2004). Living in the Environment: Principles, Connections and Solutions 13th Edition. Pacific Grove CA Brooks/ Cole-Thomson learning. 6 Groombridge, B. and Jenkins, M. D. (2002) World Atlas of Biodiversity — Earth’s Resources in the 21st Century, University of California Press. 119 ES 203 ENVIRONMENTAL SCIENCE LAB - I Total Marks : 100 1. Measurement of microclimate variables considering different parameters such as (a) air temperature; (b) wind velocity; (c) relative humidity; and (d) light intensity) and correlate with different climatic conditions and seasonal variations (i) bright sunny day, (ii) rainy day, (iii) cloudy winter day. 2. Soil analysis (a) Rapid field test for carbonates, sulphates, chloride, nitrate and base deficiency. (b) Determination of pH, field capacity, density and porosity of soil samples. (c) Study of soil texture using sieve method. (d) Observation of seedling growth in two soil populations. (e) Quantitative estimation of oxidisable organic matter present in the soil. 3. Study of ecological adaptations (through live specimens) of Hydrophytes Xerophytes 4. Study of biotic interactions in plants/animals through live materials/ museum specimens/slides/photographs; Pollination mechanisms (e.g.. Insects and flower structure) Predation— Drosera / Nephenthes Parasite —Cuscuta (stem parasite) Mutualism — Types of Lichens 120 5. Study of plant community study through field work : (a) Types of sampling methods — Quadrat, Line transect, Belt (b) Study of frequency distribution and comparison with Raunkier’s distribution. (c) Study of diversity index of plant species in the college campus. (d) Study of minimum quadrat size using species area curve. 6. Demonstration experiments: (a) Models of various ecosystems— Aquatic, Desert and Grassland. (b) Models/ photographs of Ecological Pyramids and Energy Flow. 7. Data interpretation for Ecological modeling. 8. Submission of projects on any of the following topics : (a) Energy resources (b) Environmental Impact—case studies 9. Field Visit to study ex-situ and in-situ conservation of plants and animals. Submission of field report. 10. Analysis of characters of 10 plants and 10 animals (from published sources) in the Red Data Book to draw an inference on the reason(s) behind extinction/threat/rarity. 11. To study the techniques for preservation of plants and animals in the herbarium and museum. 12. Study of different models of rainwater harvesting. 121 BIOLOGY BIO 201 BIOLOGY OF ANIMALS: FORM, STRUCTURE AND FUNCTION (Total Lectures: 75) Total Marks : 100 Unit I Classification General characteristics and outline classification of different animal groups (Up to classes for non-chordates and up to orders for chordates). Unit II Acoelomates Locomotion and Reproduction in Protista; Canal System in Porifera; Metagenesis and Polymorphism in Cnidarians; Parasitism and Parasitic adaptations in Platyhelminthes. Unit III Pseudocoelomates Parasitic adaptations and Evolution of Parasitism. Unit IV Schizocoelomates Metamerism and Excretion in Annelids; Vision and Respiration in Arthropods; Shell and Respiration in Molluscs. Unit V Enterocoelomates Water Vascular System in Echinoderms; Respiration and Osmoregulation in Fishes; Respiration in Amphibians; Terrestrial adaptations in Reptiles; Respiration and Flight Adaptations in Birds; Integument in Mammals. Unit VI Tissues and Glands Different Types of Tissues in man—Epithelial, Connective, Muscular and Nervous; Types of Glands. 122 Unit VII Tissue Physiology Membrane Potential (Action Potential) and Molecular mechanism of Muscular Contraction in human beings. Unit VIII Nutrition and Digestion in Man Mechanical and Chemical Digestion of food; Control and Action of Gastrointestinal Tract Secretions; Absorption of Digested Food. Unit IX Maintenance of Internal Body Environment w.r.t. Man: Physiological Principles of Gaseous Exchange; Transport of Oxygen and Carbon Dioxide in Blood; Physiology of Kidney and Formation of Urine. Unit X Human Circulatory System Circulatory Body Fluids; Blood Homeostasis; Heart as a pump; Conduction of Heart Beat. Unit XI Human Endocrine System and Reproduction An Overview of Endocrine Glands and Their Hormones; Physiology of Human Male and Female Reproduction. Suggested Readings 1. Barrington, E.J.W. (1971) Invertebrate Structure and Functions. E.L.B.S. and Nelson. 2. Boradale, L.A. and Potts, F.A. (1961) Invertebrates: A Manual for the use of Students. Asia Publishing Home. 3. Cambell & Reece. (2005) Biology. Pearson Education. 4. Elaine Marieb, R. N. (2002) Human Anatomy & Physiology. Benjamin/ Cummings Publishing Company, New York and London. 5. Hilderbrand, M. and Gaslow, G.E. (2001) Analysis of Vertebrate Structure. John Wiley and Sons. 123 6. Kent, G.C. and Carr R.K. (2001) Comparative Anatomy of the Vertebrates. The McGraw Companies Inc. 7. Miller, S.A. and Harley, J.B. (2002) Zoology. Tata McGraw Hill Publishing Company. 8. Parker, T.J. and Haswell, W.A. (1995) Text Book of Zoology— Vertebrates ELBS and McMillan. 9. Tortora, G.J. and Grabowski, S. (2001) Principles of anatomy and Physiology. Harper Collins. 10. Vander, A.J. Sherman, J.H. and Luciano, D.S. (1975) Human Physiology—The Mechanisms of Body Function. McGraw Hill Publishing Co. 124 BIO 202 BIOLOGY OF PLANTS : FORM, STRUCTURE AND FUNCTION (Total Lectures: 75) Total Marks : 100 Unit I Diversity of Plants Evolutionary trends Unit II Plant Systematics Taxonomic hierarchy (Kingdom, Division Class, Order, Family, Genus, Species); nomenclature, artificial, natural, and phylogenetic systems of classification (Bentham and Hooker’s, Takhtajan’s systems); biosystematics. Unit III Viruses and Bacteria A general account of structure and reproduction; economic importance. Unit IV Algae Diagnostic features of identification; morphology, reproduction and classification with special reference to Volvox, Spirogyra, Vaucheria, and Polysiphonia; economic importance (a general account). Unit V Fungi Diagnostic features of identification; morphology, reproduction and classification with special reference to Rhizopus, Penicillium, Puccinia and Agaricus; lichens (a general account); economic importance of fungi and lichens. Unit VI Archegoniatae Characteristic features of identification, classification and reproduction of Bryophytes and Pteridophytes with special reference to Marchantia, Funaria, Selaginella, and Pteris; concept of apogamy and apospory; economic importance of bryophytes and pteridophytes. 125 Unit VII Gymnosperms Important characteristic features, classification, study of vegetative structures and reproduction of Pinus, Cycas; economic importance of gymnosperms. Unit VIII Angiosperms Anatomy of root, stem, leaf; structure and function of xylem and phloem; economy botany of rice, wheat, cotton, spices, cinchona, tectona, mustard, tea and rubber (a general account); ecological anatomy. Unit IX Water Relations Absorption, transport, transpiration. Unit X Nutrition Essential elements, micro and macronutrients, physiological basis of mineral deficiency, transport of nutrients, biological nitrogen fixation. Unit XI Photosynthesis Photosynthetic pigments, mechanism of photosynthesis (light & dark) reactions; distinguishing features of C3, C4 and CAM pathways of carbon fixation. Unit XII Respiration Aerobic respiration, anaerobic respiration fermentation (different types); glycolysis, Kreb’s cycle, electron transport chain, pentose phosphate pathway. Unit XIII Growth and Development Seed dormancy (causes and methods of overcoming), photoperiodism, vernalization, phytohormones (auxins, cytokinins, gibberllins, ethylene, polyamines), signal transduction (overview). 126 Suggested Readings : 1. Alexopoulos, C.J., C.W. Mims and Blackwell, (1996) Introductory Mycology. 4th ed., John Wiley and Sons Inc. 2. Bhatnagar, S. P. & Moitra, A, (1996) Gymnosperms. New Age Int. Publ. House, New Delhi. 3. Carlquist, S. (1981) Comparative Plant Anatomy. Holt, Rienhart & Winston, New York. 4. Gurcharan Singh (2004) Plant Systematics — Theory and Practice (2nd Ed.) Oxford & IBH Publishing Co. Pvt. Ltd. New Delhi. 5. Hopkins, W.G. (1999) Introduction to Plant physiology. John Wiley and Sons, New York. 6. Lee, R.E. (1999) Physiology (3rd edition, earlier 1989 - 2nd edition). 7. Moore, R. Clarke, W.D., and Vodopich, D. S. (1998) Botany (2nd edition), McGaw-Hill, New York. 8. Rashid, A. (1999) An introduction to Pteriodophytes, 2nd ed. Vikas Publ. House Pvt. Ltd., New Delhi. 9. Raven, P.H., Evert, K.F., and Eichhorn, S.E. (1999) Biology of Plants (5th edition). W.H. Freeman and Co. Worth Publishers, New York. 10. Willis, K.J. and McElwaine, J.C. (2002) The Evolution of Plants, Oxford University Press. 11. Black J.G. (2005) Microbiology: Principles and Exploration 6th edition, John Wiley & Sons. 127 BIO 203 BIOLOGY LAB - I Total Marks : 100 I. Biology of Animals : Form, Structure and Function 1. Study of Specimens: Amoeda, Euglena, Paramecium, Leucosolenia, Sycon, Spongilla, Physalia, Aurelia, Tubipora, Metridium, Taenia, Ascaris, Ancylostoma, Neries, Aphrodite, Hirudinaria, Palaemon, Cancer, Palamnaeus, Julus, Scolopendra, Bombyx, Apis, Chiton, Dentalium, Pila, Pinctada, Octopus, Asterias, Echinus, Cucumaria, Antedon, Petromyzon, Pristis, Electric Ray, Hippocampus, Clarias, Gambusia, Labeo, Uraeotyphlus, Salamandra, Rhacophorus, Chameleon, Draco, Uromastix, Anguis, Naja, Python, Viper, Model of Archeopteryx, 3 Common Birds (Crow, Duck, Owl), Squirrel and Bat. 2. Study of Permanent Slides: T.S. Sycon, T. S. Unio Gill, T.S. Starfish through Arm 3. Temporary Mounts: Septal and Pharyngeal Nephridia of Earthworm; Mouth Parts of Cockroach; Placoid, Cycloid and Ctenoid Scales; Squamous Epithelium; Striated Muscle; Nerve Cell and Blood Film. 4. Dissections: Digestive System and Nervous System of Cockroach; Afferent branchial System of Scoliodon; Urinogenital System of Rat. 5. Preparation of Haemin and Hemochromogen Crystals. 6. Enumeration of total leukocytes using Haemocytometer. 7. Estimation of Haemoglobin Content of Blood using Sahli’s Haemoglobinometer. 8. Pulmonary Volume recording in Humans using Spirometer. 9. Recording of Blood Pressure using Sphygmomanometer. 10. Examination of sections of Oesophagus, Stomach, Ileum, Pancreas, Kidney, Lung, Adrenal. Thyroid, Ovary and Testis. 128 II. Biology of Plants: Form, Structure and Function Marks: 50 1. Viruses: EM of TMV and Bacteriophage, study specimens of virus infected plants (any two). 2. Bacteria: Types through permanent slides/photographs, specimens of infected plants (any two). 3. Algae: Study of permanent slides and classification of (a) Volvox, (b) Spirogyra, (c) Vaucheria, (d) Polysiphonia. 4. Fungi: Mount material to study, and classification, thallus and reproductive structures in (a) Rhizopus, and (b) Penicillium. Study from the permanent slides or specimen along with classification: (a) Rhizopus, (b) Penicillium, (c) Puccinia, (d) Agaricus. Lichen morphology along with classification. 5. Bryophytes: Study of (a) Marchantia from specimen and permanent slides only, (b) Funaria: detailed study and classification from W.M. rhizoids, leaf, operculum, peristome, spores and permanent slides of archegonia, antheridia and capsule. 6. Pteridophytes: Study of (through temporary/permanent slides) and classification of (a) Selaginella, (b) Pteris: detailed study of T. S. of rachis, V.S. of sporophyll and W.M. of sporangium. 7. Gymnosperms: Study of Cycas and Pinus from specimens and permanent slides only. 8. Angiosperms: Taxonomic study of characters of one plant from each of the following families: (a) Brassicaceae, (b) Solanaceae, (c) Asteraceae (d) Liliaceae, (e) Poaceae. Classification according to the system of Bentham and Hooker. Study of the following tissues from permanent slides or by maceration; Parenchyma, Collenchyma, Schlerenchyma, Xylem and Phloem. Study of anatomy of root, stem and leaf through permanent slides. 9. Study of Economic characters of following sps: Rice, Wheat, Cotton, Tectona, Mustard, Tea, Rubber Tree, Clove and Pepper. 129 10. Determination of Osmotic potential in epidermal peel of Rhoeo discolor. 11. To study the water potential using potato tuber. 12. Study of stomatal index, stomatal frequency of any plant. 13. To study the effect of light and wind on the rate of respiration. 14. To study the effect of CO2 and light on the rate of photosynthesis. 15. Demonstration of anaerobic respiration by Kuhn’s funnel. 16. To study the rate of respiration in different parts of plants (any two). 17. To demonstrate Hill’s reaction. 130 AGROCHEMICAL AND PEST MANAGEMENT ACP 201 AGRICULTURAL BOTANY, PLANT PATHOLOGY AND WEEDS Maximum Marks-100 Unit A : Agricultural Botany Seed Physiology - Seed dormancy, types, factors causing dormancy, mechanism and methods for breaking seed dormancy, seed viability, seed vigour, hormonal regulation of seed dormancy and germination. Physiology of Growth and Yield - Principal of growth analysis, sourcesink relationship, factors affecting growth, dry matter partitioning and yield, crop simulations and modeling, use of controlled environment for plant growth and development studies, concept of phytotronics. Chemical Regulation of Growth and Development - Role of hormones in plant growth and development, commercial applications of growth regulators, growth retardant and its usefulness. Reproductive Physiology and Senescene - Photoperiodism, flowering response, photo perception, critical photoperiod, photo-induction, phytochrome and its role in flowering, hormonal regulation, vernalization, physiology of fruit ripening, senescence, regulation of senescence. Unit B : Plant Pathology Introduction to Plant Pathology - Importance, concepts and types of plant disease symptoms, causes and classification of diseases. Fungal Diseases: Causal organism, symptomatology, disease cycle, prevention and control of the following fungal diseases: - White rust of crucifers - Late blight of potato - Downy mildews - Powdry mildews 131 - Rusts of wheat - Smut of wheat and barley Bacterial Diseases - Causal organism, symptomatology, prevention and control of the following bacterial diseases - Citrus canker - Angular leaf spots of cotton Viral Diseases - Causal organism symptomatology, prevention and control of the following viral diseases - Tobacco mosaic - Yellow mosaic of soybean - Control — Transmission and Control of Plant Diseases Unit C : Weeds Biology of Weeds - Ecology of weeds, competition, reproduction of weeds. Seed biology. Weed Management Practices - Mechanical Practices, Cultural Practices, Biological control. Chemical Weed Control - Herbicide classification, Selectivity of herbicides, absorption and translocation of herbicides, Mode of action of herbicides, Detoxification mechanisms of herbicides. Weed resistance to herbicides. Formulation of herbicides. Weed Control Methods : Weed control in wheat, rice and vegetable crops. Control of five abnoxious weeds. Integrated pest management. Suggested Readings 1. Tai Z, and E. Zeiger, Plant Physiology, The Benjamin/Cumming Publishing Co. 2. W. G. Hopkins, Introduction to Plant Physiology, John Wiley and Sons Inc. USA 3. R. C. Mandal, Weed, Weedicides and Weed Control: Principle and Practice, Agro Botanical Publishers, Delhi. 132 4. S. Subramanian, All about weed control. Kalyani Publishers. 5. F. M. Ashton and T. J. Monaco, Weed Science: Principles and Practices. John Wiley and Sons. Inc. 6. V. S. Rao, Principles of Weed Science. Oxford and IBH Publishers, New Delhi. 7. G. N. Agrios. Plant Pathology, Academic Press, USA. 8. R. S. Singh, Plant Diseases, Oxford and IBH. 9. R. S. Mehrotra, Plant Pathology, Tata McGraw Hill, New Delhi. 10. O. P. Sharma, Textbook of Fungi, Tata McGraw Hill, New Delhi. 133 ACP. 202 FERTILIZERS, HERBICIDES, FUNGICIDES (Total Lectures : 72) Total Marks : 100 Unit-I Fertilizers Types of fertilizers, macro nutrients and micro nutrients. Classification, uses and residual effect of nitrogen, phosphate and potassium fertilizers. Fertilizer quality control: Principles involved in the analysis of fertilizers; Chemical titrimetric, methods for estimation of fertilizers. Economics aspects of fertilizers: Growth and present state of fertilizer industry in India. Effects of fertilizer production on environmental pollution. Unit-II Herbicides Classification, selectivity and uptake of herbicides, chemical, mode of action of the following classes with special reference to the individual compounds mentioned: (a) Aryl alkanoic acids; 2, 4 DMCPA, dicamba and dichlorobenzil, dalapon. (b) Aromatic carbamates, barban and asulam. (c) Triazines; simazine. (d) Bipyridiniums and paraquat (e) Sulfonylurea: Chlorosulfuron (f) Uracils : Bromacil (g) Ureas : Monuron and Isoprotureon Unit-III Fungicides Types of fungicides, mode of action; Chemistry of the following: (a) copper and mercury derivatives (b) Dithiocarbamates; thiram, ziram, nabam, 134 (c) Dinitro phenols; 2, 4-dinitro o-cresol (DNOC) karathane (d) Quinines; dichlone (e) Benzimidazoles, benomyl. (f) Organo phosphorus fungicides: Kitazine (g) Phenyl amides: Metalaxyl (h) Triazoles : Propiconazole (i) Thiophanates : Thiophanates. Role of fumigants and fumigation techniques. Suggested Readings 1. K. S. Buchal. Chemistry of Pesticides, John Wiley and Sons. 2. J. L. Havlin, J. D. Baton, S. L. Tisdali and V. L. Nelson. Soil fertility and fertilizer. Pearson Education, USA. 3. A. S. Crafts. Chemistry and mode of action of herbicides, John Wiley. 4. Fertilizers, Manual, UNIDO. 5. Hanbook Fertilizers. Fertilizer Association of India. 6. R. Cremlyn. Pesticide preparation and mode of action. John Wiley. 7. K. A. Hassal. Chemistry of Pesticides, McMillan Press. 8. A. C. Edwards. Pesticides in the environment, CRC Press. 9. N. N. Melnikov, Chemistry of Pesticides, MIR Publications. 135 ACP 203 AGROCHEMICALS AND PEST MANAGEMENT LAB -I Total Marks : 100 PART - I 1. To study opening and closing of stomata. 2. To determine stomatal index of the given leaf. 3. To study the effect of ethylene on shelf life of cut flowers. 4. To study the effect of cytokinin on leaf senescence. 5. To study effect of heavy metals on growth and development. 6. To study some common fungal diseases of crop plants. 7. To test the viability of weed seeds. 8. To find organic matter of soil. 9. To evaluate allelopathic effects of weeds on seed germination of crop seeds. 10. To evaluate effect of herbicides on seed germination and seedling growth of weeds. PART - II 1. Determination of Moisture content in urea by Karl Fisher method. 2. Estimation of Biuret in urea. 3. Determination of Free acidity in ammonium sulfate (Titrametric) 4. Determination of calcium nitrate in calcium ammonium nitrate. 5. Determination of urea in given urea sample. 6. Determination of chlorides other than ammonium chloride in ammonium chloride fertilizers. 7. Determination of Zinc in zinc sulphate. 8. Preparation of 2, 4-D, zineb, Bordeaux mixture. 9. Estimation of water soluble phosphorus in single and triple super phosphates. 136 MATHOPHYSICS (For B3, B4 and D4 Combination) MP 201 MATHEMATICS-1 (Four Lectures plus one tutorial per week) Internal Assessment 38 marks Total marks 150 Examination 112 marks Duration 3 Hours Unit I : Geometry and Vector Calculus (35 L) 38 Techniques for sketching parabola, ellipse and hyperbola. Reflection properties of parabola, ellipse and hyperbola. Classification of quadratic equations representing lines, parabola, ellipse and hyperbola. Polar equations of conic sections. Rectangular coordinates in 3-space: spheres, cylindrical surfaces cones, and vectors - viewed geometrically vectors in coordinate system, vectious determine by length and angle, dot product, cross product and their geometrical properties. Parametric equations of lines in plane, planes in 3- space. Differentiation of vector valued functions, gradient, divergence, curl and their geometrical interpretation. Unit II: Calculus (45 L) 58 Definition and techniques for finding asymptotes singular points, concavity, convexity, points of inflexion for functions. Tracing of standard curves. Integration of irrational functions. Reduction formulae. Rectification. Quadrature. Volumes and Surfaces of revolution. Limit and continuity of a function: (e, d) and sequential approach. Properties of continuous functions including intermediate value theorem. Uniform continuity. Differentiability. Derboux’s theorem, Rolle’s theorem. Lagrange’s 137 mean value theorem, Cauchy mean value theorem with geometrical interpretations. Unit III: Geometry of complex numbers and polynomial equations (16 L) 16 Geometrical representation of algebraic operations on complex numbers. Section formula, Centroid, Incentre, orthocentre and Circumcentre of a triangle in complex form. Lines, half planes, circles, discs in terms of complex variables. Statement of the Fundamental Theorem of Algebra and its consequences. Relation between roots and coefficients for a polynomial equation. Results about occurence of repeated roots, rational roots, surd roots and complex roots. De Moivre’s theorem for rational indices and its simple applications. Recommended Readings 1. H. Anton. I. Bivens and S. Davis, Calculus, John Wiley and Sons Pvt. Ltd, 2002. 2. Frank Ayres, Jr. & Elliott Mandelson, Calculus, Fourth Edition, Tata McGraw Hill, 2005. 3. E. Fischer, Intermediate Real Analysis, Springer Verlag, 1983. 4. A. I. Kostrikin: Introduction to Algebra, Springer Verlag, 1984. 5. K. A. Ross, Elementary Analysis – The Theory of Calculus Series— Undergraduate Texts in Mathematics, Springer Verlag, 2003. 6. S. L. Salas, E. Hille and G. J. Etgen, Calculus of one and several variables, John Wiley and Sons, Inc., 1999. 7. Murray R. Spiegel, Vector Analysis, Tata McGraw Hill, 2005. 8. G. B. Thomas and R. L. Finney: Calculus and Analytic Geometry, Pearson Education (Singapore), 2001. 138 MP 202 THERMAL PHYSICS AND ELECTROMAGNETISM (70 Lectures) Total Marks : 100 Thermodynamics: (10 L) Zeroth and first law of thermodynamics. Reversible and irreversible processes. Carnot’s cycle, Carnot’s theorem. Second law of thermodynamics and entropy. Thermodynamic temperature. Entropy change in reversible and irreversible processes. Thermodynamic potentials. Enthalpy, Gibbs’ and Helmholtz’s functions. Kinetic Theory (10 L) Derivation of Maxwell’s law of distribution of velocities and its experimental verification. Law of equipartition of energy and its application to specific that heat of gases. Mean free path, Drude’s theory of metallic conduction. Statistical Mechanics (15 L) Recapitulation of micro and Macro states, thermodynamic probability. Partition function, Entropy, Maxwell-Boltzmann distribution. Thermodynamic properties of ideal gas. Bose- Einstein distribution function, thermodynamic properties of photon gas, Planck’s Law, Rayleigh Jean’s and Wein’s Law displacement law and Stefan- Boltzman Law. Fermi- Dirac Statistic, Completely degenerate Fermi gas. Electromagnetism (35 L) Coulomb’s law, electric field intensity and electric potential. Gauss’s law and its applications. Electric field in a dielectric media. Magnetic induction and Bio-Savart law. Divergence and curl of magnetic induction. Lorentz’s force on a point charge. Charged particle dynamics in uniform electric and magnetic field. Ohm’s law, electromagnetic force, Faraday’s law of electromagnetic induction. Energy stored in magnetic field. 139 Conservation of charge, modification of Ampere’s law, Maxwell’s equations in vacuum and in matter. Boundary conditions. Electromagnetic waves; Wave equation, plane wave solution, transverse nature, wave velocity, description of linear, circular and elliptical polarization pointing theorem. Electromagnetic waves in non-conducting and conducting medium, reflection and refraction at normal incidence, skin depth. Wave propagation in dilute ionized media. Recommended Readings F. W. Sears and G. I. Salinger: Thermodynamics. Kinetic Theory and Statistical Thermodynamics. David J. Griffiths: Introduction to Electrodynamics, 2nd Edition (Prentice Hall India). 140 MP 203 PHYSICS LAB - I Total Marks : 50 1. Determination of Stefan’s constant. 2. Thermal conductivity of good conductor by Searle’s method. 3. Temperature coefficient of resistance by PRT. 4. Calibration of Thermocouple. 5. Joule mechanical equivalent by Callender and Barnes method. 6. Low resistance by Carey foster’s bridge. 7. Study of ballistic galvanometer (charge sensitivity, CDR) 8. Ratio of capacitances by De Saughty’ method. 9. Mutual inductance by absolute method. 10. High resistance by leakage method. 11. Self inductance by Anderson’s bridge (ac). 12. B-H curve solenoid. Note : At least eight experiments should be performed by each student. 141 SERICULTURE SC. 201 GENERAL SERICULTURE AND SOIL SCIENCE (75 Lectures) Total Marks: 100 Section - A — General Sericulture 1. Introduction to sericulture (3 L) Introduction, scope of sericulture. 2. Origin & History of Sericulture (5 L) Origin of Sericulture, Silk Road, Spread of sericulture to various parts of world. 3. Silk Industries (5 L) World silk production, Production of silk in India, Export potential & exports from India, An overview of silk industries in the world with special reference to India. 4. Different types of Sericulture (18 L) Mulberry & Non-mulberry sericulture-Introduction and their importance, Mulberry sericulture practices in different conditions, factors affecting silk production. Non Mulberry Sericulture: Wild Silks/ Vanya Silks of India, Different types of Non Mulberry silks — tasar, eri and muga and their culture — Primary and secondary food plans, propagation of primary food plants, morphological features of silkworms, rearing techniques, seed cocoon production/grainage operations, pathogens, pests and predators, reeling process — traditional and modern, reeling and weaving sectors, employment potential. 5. Sericulture Education & Development (10 L) Extension education, role of sericulture in rural development, Communication, Extension teaching methods, Importance of sericulture education, Sericulture education through universities, research institutes, NGO and other related organizations Role of various agencies in spreading sericulture at state and national level, 142 need for sericulture development, Financial support system in India. Economics of sericulture. Section - B — Soil Science 1. Introduction to soils (8 L) Classification, types of rocks, soil profile, factors affecting soil development, Chief soil types of India. 2. Physical Properties of soil (10 L) Soil texture, structure, density and porosity, permeability, colour, temperature, plasticity, cohesion and adhesion, aeration, drainage. Soil Water — Classification, measurement, irrigation, management. 3. Chemical properties of soil (13 L) Inorganic and organic components, Colloidal properties of many clays, Fe-AI oxide clays, isomorphous substitution Percent base saturation, Soil reaction and buffering action, factors affecting soil fertility, availability of nutrients in soil, Problem soils and their reclamation. 4. Soil organic matter (5 L) Humus, role of humus, factors affecting rate of humification, Nitrogen and organic matter management in soil, role of soil microorganism. 5. Soil requirement for mulberry (2 L) Physical and chemical properties of soil required for mulberry. Suggested Readings 1. Agarwal, H. O. and Sethi, M. K.: Sericulture in India - Volume - I, 2000, Bishen Singh Mahendra Pal Singh Publishers and Distributors of Scientific Books, Dehradun. 2. FAO United Nations, Rome: F A O Manuals on Sericulture (Volume I— Mulberry Cultivation, II — Silkworm Rearing, III — Silk Reeling, IV — Non-Mulberry Silks), FAO, united Nations, Rome. 3. Koshey, T.D.: Silk: Production and Export Management, Ashish Publishing House, New Delhi. 143 4. Koshey, T.D.: Silk Exports and Development, Ashish Publishing House, New Delhi. 5. Brady, N. C.: Nature and Properties of Soil, 9th Edition, The Macmillan Publishing Co., Reprint, 1998. 6. Shukla, R. S. and Chandel, P. S. : Plant Ecology and Soil Science, 9th Revised and Enlarged Edition, S. Chand & Company Ltd., 2000. 144 SC 202 MULBERRY AND SILKWORM STUDIES (75 Lectures) Total Marks: 100 Section - A — Mulberry 1. Introduction to Mulberry (10 L) Salient features of Moraceae, Mulberry, Distribution, Factors affecting Habitat, morphology and variations, Important Cultivars of Mulberry and their characteristics, Anatomy and Embryology, Economic Importance of Mulberry with special reference to sericulture. 2. Mulberry Physiology (8 L) An Overview of transpiration, photosynthesis, phytohormones, relation between growth and environment, water stress and physiological consequences, role of essential elements. 3. Establishment of Mulberry Garden (6 L) Under irrigated and rain fed conditions, Planting Season, Selection and Preparation of Land, Selection and planting of Material, Planting systems, Inter cultivation practices. 4. Propagation of Mulberry (12 L) Nursery practices, propagation through various methods, manures and fertilizers, inter cultivation practices, mulching and weed management, plant nutrition management, water management in mulberry cultivation, pruning and its significance, leaf harvesting and effects on mulberry, harvesting methods, transportation and preservation of mulberry leaves. 5. Estimation of Leaf Yield and Economics (3 L) Importance of Leaf Quality and Quantity, Leaf — Cocoon ratio, Economics of Mulberry cultivation. 145 Section - B — Silkworm 1. Introduction to Silkworm (5 L) Systematic position and characteristic features, classification on the basis of geographical regions, moultinism and voultinism, life cycle. 2. Anatomy and Physiology (20 L) Study of different organ systems — digestive, excretory, respiratory, circulatory, muscular, nervous and reproductive, Glands and their secretions. Silk Glands — Location, structure and function, embryonic development. Concept of synthetic diet in sericulture. 3. General Account of disinfectants and relative efficiencies (3 L) 4. Silkworm Rearing (8 L) Rearing Appliances and their disinfection; Different rearing methods and practices; Different phases of silkworm culture, rearing in traditional and non-traditional areas. Suggested Readings 1. Agarwal, H. O. and Sethi, M. K. : Sericulture in India — Volume - II & III, 2000, Bishen Singh Mahendra Pal singh Publishers and Distributors of Scientific Books, Dehradun. 2. FAO United Nations, Rome: FAO Manuals on Sericulture (Volume I - Mulberry Cultivation, Volume - II — Silkworm Rearing, FAO, United Nations, Rome. 3. Ganga, G. and Shetty, J. S. : Introduction to Sericulture, Oxford & IBH Publishing Co. Pvt. Ltd., 1991. 4. Jolly, M. S.: Appropriate Sericulture Techniques, Director, ICTRETS, 1987. 5. Sarkar, Dilip De: Silkworm Biology., Breeding and Genetics, 1st Edition, Vikas Publishing House Pvt. Ltd, 1998. 146 SC 203 SERICULTURE LAB - I (Based on Paper SC 201 & SC 202) Total Marks: 100 1. Sericulture maps of the world and India, Silk Road, organizational set up of Sericulture in India. 2. Preparation of histogram, pie charts and line graphs on important sericultural data e.g., World silk production, Silk and other silk fibers in India, Different types of silk production in India, Mulberry silk production in different states, Mulberry and non-mulberry silk production in India, Silk production over period of ten years, Silk yarn and other textile fibers production over period of ten years. 3. Identification and study of sericulture products. Different types of Cocoons and silk yarn. Identification and study of sericulture byproducts: pupae, silk waste, spun yarn, noil yarn and other byproducts. 4. Comparative account of economics of sericulture and other cash crops e.g., tobacco. sugarcane, cotton etc. 5. Morphological study of primary food plants of non-mulberry silk worms. 6. Morphology of egg., larvae, pupae and moths of different non-mulberry silkworms. 7. Study of appliances used in rearing and seed preparation of nonmulberry silkworms. 8. Study of different reeling machines in non-mulberry sericulture (drawing and sketches), (identification of different yarns. 9. Microscopic observation of different pathogens of non-mulberry silkworms. 10. Soil sample analysis: Soil profile, soil colour, bulk and particle density, porosity, water holding capacity, pH, electrical conductivity, CaCO3 organic carbon, nitrogen, phosphorus potassium and sodium content. 147 11. Preparation of Non-Projected visual aids for sericulture extension purpose, Result and Method Demonstration, Use of Audio Visual Aids. 12. Conduction of survey at a village level to study the rate of adoption of any one technique through questionnaire method. 13. Preparation of Sericulture Project & Feasibility report for taking up sericulture in a new area. 14. General habitat and structure of mulberry plant. 15. Botanical aspects of Mulberry — Inflorescence, flower, fruit, floral formula and diagram. Anatomy: Structure of primary and secondary root, stem, Structure of mulberry leaf. 16. Identification of different mulberry varieties e.g., V-1, K-2, Mysore local, S-13, S-34, S-36, S-54. 17. Propagation and nursery preparation, Cultivation practices for irrigated and rain-fed conditions, Calculation of manures and fertilizer doses. 18. Common Weeds and their control. 19. Harvesting methods and estimation of leaf yield. 20. Characteristics of some evolved varieties of mulberry, study of disease resistant and draught tolerant genotypes of mulberry. 21. Study of bio fertilizers, green manures, growth hormones used in mulberry cultivation. 22. Microchemical tests for detection of proteins in mulberry. 23. Biochemical analysis of leaves of various mulberry cultivars for soluble proteins, crude proteins, ash content, chlorophyll (a , b and total) and moisture percentage. 24. Study of life cycle of Bombyx mori, morphology of different stages and sexual dimorphism. 25. Dissection and display of Digestive system, Silk glands, Nervous system, Reproductive system of male and female moth and mounting of mouth parts and spiracles. 148 26. Cocoon characters of different silkworm races — univoltine, bivoltine and multivoltine races. 27. Disinfectants — Different types, concentration and preparation. 28. Silkworm Rearing — Models of rearing houses, rearing appliances and their uses. A complete silkworm rearing program and submission of silkworm life cycle and rearing report. 29. A Visit to pre cocoon sector of sericulture, research institutes. 149 ELECTIVE SUBJECTS One Elective Subject in II year may be chosen out of the following: Sr. No. Subject 1. Economics 2. Entrepreneurship 3. Organizational Behaviour 4. Psychology 5. Financial Accounting 6. Financial Management OR A Project of equivalent weightage in any one of these elective subjects. 150 EL 210 (i) : ECONOMICS (Total Lectures: 50) Total Marks: 50 The purpose of this course is to expose the students of science stream to the basic principles and concepts of Economics. Unit I: Microeconomics What economics is all about: Choice making and the concept of opportunity cost; Micro and macroeconomics; Positive and normative economics; Construction of an economic theory. Market forces of demand and supply: Determinants; Market equilibrium; Role of price mechanism in solving central problems of an economy. Consumer’s behaviour: Consumer’s equilibrium and law of demand through ‘utility analysis’ and ‘indifference curve analysis’. Price elasticity of demand. Consumer surplus. Producer’s Behaviour: Input - Output relation; output-cost relation; Price elasticity of supply. Price determination and equilibrium of firm: Rules of equilibrium of firm; Price determination and equilibrium of firm under perfect competition, monopoly and monopolistic competition; Game theory— Dominant strategy, Nash equilibrium, and Prisoners’ Dilemma. International trade: Basis; Theory of comparative cost advantage; sources of comparative advantage. Unit - II: Macroeconomics Issues; National income — meaning and the three approaches; Concepts of economic growth, economic development, economic welfare and sustainable development. Money: Meaning; functions; money supply. 151 Banking: Basic Structure; Commercial banks — functions, creation of money. Central bank — functions, regulation of credit creation. Balance of payments: Meaning; format (India); autonomous and induced transactions. Foreign exchange: Meaning; Determination of foreign exchange rate. Government budget: Format (India); taxation; government expenditure; fiscal deficit (basic elements only). Suggested Readings 1. Karl E. Case and Ray C. Fair Principles of Economics, Prentice Hall, Pearson Education, (6th Ed.). 2. R. Lipsey and A. Chrystal; Economics, Oxford University Press, (10th Ed.). 152 EL 210 (ii) ENTREPRENEURSHIP ( 50 Lectures) Total marks: 50 The purpose of this paper is to provide to the students of science an awareness and appreciation of the desirability and feasibility of entrepreneurship as an alternative career option vis-a-vis employment. Unit I Introduction to the world of business and entrepreneurship. The spectrum of business activities— industry, trade and commerce. Growing importance of services sector in the economy and the resurgence of Indian manufacturing sector. An awareness of the forms of business organization. Meaning and importance of entrepreneurship. Role and functions of entrepreneurs in relation to the business and in relation to economic development. Virtues of being your own boss (YOB) vis-à-vis JOB. Unit II Entrepreneurship as an interface between the personal abilities and motivations and the environmental influences. Theories of entrepreneurship with emphasis on resource based theories. Role of personal resources — business background, education and work experience and technical, conceptual and interpersonal skills. Entrepreneurial motivation. Contemporary role models from the world of business. (The students may be advised to read Business Magazines and Browse the internet for writeups on living entrepreneurs). Entrepreneurial environment impact of WTO on entrepreneurship. Dynamics of the relationship between science, technology and entrepreneurship. Roles of technology parks, business incubators and venture capital. Unit III Opportunity scouting for business venturing. Primary and secondary sources of information on business opportunities. Schemes of entrepreneurship development, especially those relating to science and technology entrepreneurship. Salient sectors and prominent clusters of entrepreneurship. (The students may be advised to focus on the chosen 153 one, two or three industries and examine their structure thoroughly). Emerging business opportunities: Franchising, Multilevel Marketing, E-commerce and Business Process Outsourcing. Unit IV Test of feasibility for the proposed business idea and development of a business plan. Aspects of techno-economic and commercial-financial and legal-administrative feasibility. Issues in developing and presenting a business plan. Role of consultancy organizations and utility of off the shelf project Reports. Unit V Mobilising resources for implementing the business plan. Industrial accommodation, utilities, capital and human resources. Implementation schedule. Review of the process of entrepreneurship in a business lifecycle context. Suggested Readings 1. Gupta, C. B. and Srinivasan, Entrepreneurship and Small Business Development, New Delhi, Sultan Chand & Sons. 2. Dollinger, Marc J., Entrepreneurship: Strategies and Resources Illinols, lrwin. 3. Saxena, Anand, Entrepreneurship; Motivation, Performance and Rewards, Deep & Deep Publications, New Delhi. 154 EL 210 (iii) ORGANISATIONAL BEHAVIOUR (50 Lectures) Total Marks: 50 The purpose of this paper is to provide the students of science, a basic understanding of the concepts and processes of organisational behaviour to equip them with the necessary skills to manage human behaviour at work. Unit I: Introduction Significance of Organisational Behaviour Contribution of Psychology, Sociology and Anthropology to the field of Organisational Behaviour. Models of Organisational Behaviour. Basic Roles of Managers. Unit II: Individual in the Organisation Personality : Traits and Types. Attitudes and Values. Perception — Process and Factors. Rationality in Decision-Making. Motivation — Maslow and Herzberg Models. Role of Incentives. Unit III: Interpersonal Behaviour Transactional Analysis — Ego States, Life Positions. Interpersonal Conflicts, Interpersonal Communication. Unit IV: Group Behaviour Group Dynamics. Informal Organisation. Team decision-making. Leadership — Concept and Styles. Unit V: Contemporary Issues in Organisational Behaviour Creating and Sustaining Organisational Culture. Managing Workforce Diversity. Managing Change and Creating Learning Organisation. 155 Suggested Readings 1. Davis, Keith, Organisational Behaviour : Human Behaviour at work, Tata McGraw-Hill, New Delhi, 1999. 2. Luthans, Fred, Organisational Behaviour, Tata McGraw-Hill, New Delhi, 2003. 3. Sharma, R. A., Organisational Behaviour, Sultan Chand & Sons, New Delhi, 2005. 4. Mirza, Saiyadain, Organisational Behaviour, Tata McGraw-Hill, New Delhi, 2001. 5. Chhabra, T. N., Organisational Behaviour, Dhanpat Rai & Co., Delhi, 2006. 6. Chopra, R.K. Organisational Behaviour, Sun India, Delhi, 2005. 7. Pareek Udai, Understanding Organisational Behaviour, Tata McGraw- Hill, New Delhi, 2001. 156 EL 201 (iv) : PSYCHOLOGY (Total Lectures: 50) Total Marks: 50 The objectives of this course is to provide the students an up-to-date knowledge of the key concern of psychology in context of the Self and others. The course also intends to develop an understanding of the problems and concerns of everyday life and the strategies for healthy living. Unit I Introduction to Psychology Nature and Perspective Definition, Psychology as a Science, History of Psychology — Early schools to Modern perspectives, Methods, Scope and application — various fields of Psychology. Unit II Emotions Understanding of emotions — Definition, Physiological basis, theories; Expressing emotions verbal and non-verbal expressions; Management of emotions. Unit III Self and Motivation Understanding self and self-concept, Meaning of Motivation — Definition, Motivational cycle, types of motivation; Personal Motivation — self-direction and self-efficacy. Unit IV Social Influences Social perception — Impression formation and attribution. Social influence — conformity; Social relationships — inter-personal attraction, Development and maintenance of relationships. Unit V Stress and well being: Meaning of stress; Causes and reactions to stress; Coping and managing stress; well being — Meaning and Promotion. 157 Suggested Readings 1. Morgan, C.T. King, R. A., J.R. & Schopler, J., Introduction to Psychology, Tata McGraw India, (2002). 2. Kassin, S. Psychology., Prentice-Hall Inc. New York. 2001. 3. Atwater. E., Psychology for Living Adjustment, Growth and Behaviour Today, Prentice-Hall India, 5th Ed. 4. Myers, D. G. Social Psychology. Mc-Graw Hill, 1999. 5. Taylor, S. E., Health Psychology, Mc-Graw Hill, 1999. 158 EL 210 (v) : FINANCIAL ACCOUNTING (50 Lecture) Total Marks: 50 The objective of this paper is to acquaint the students with basic concepts and techniques of financial accounting for business concerns and exposure to the published financial statements. Unit I Financial Accounting Meaning, objectives and users. Theory base of accounting including conceptual framework, Generally Accepted Accounting Principles (GAAPS) and An overview of accounting standards issued by the Institute of Chartered Accountants of India. Basis of Accounting— Cash and Accrual. Unit II Accounting process (Journal, Ledger and Trial Balance) and preparation of financial statements for non-corporate form of business. Unit III Accounting for depreciation Straight Line Method and Written down Value Method. Inventory Valuation: FIFO and Weighted Average Method. Unit IV Accounting for companies As per the requirements of the Companies Act, 1956. Preparation of the financial statements as per Schedule VI of the Companies Act: Horizontal form and Vertical form. Unit V Financial Statement Analysis Ratios Analysis. Cash flow statement as per accounting standard - 3. 159 Suggested Readings 1. Karl S. Warren & James M. Reeve & Philip E. Fees, Financial Accounting, Thomas Asia Private Limited, Singapore, First Indian Reprint, 2003. 2. Shukla, Grewal and Gupta, Advanced Accounts, Vol. I and 2 , S. Chand & Company, (2005). 3. Sehgal Ashok and Sehgal Deepak. Advanced Accounting Vol. 1 and 2, Taxmann Allied Co. Private Limited, (2005). 4. Monga J. R., Financial Accounting, Mayur Paper Book, New Delhi, (2005). 5. Gupta Nirmal, Financial Accounting, Sultan Chand & Sons, (2005). 160 EL 210 (vi) : FINANCIAL MANAGEMENT (50 Lectures) Total Marks: 50 The objective of the paper is to acquaint the students with basic concepts of financial management. It deals with short-term as well as long-term investment and financing decision. Unit I Introduction to Financial Management Its nature and scope. Type of Financial decisions. Objectives of Financial Management. Time value of money. Concept of risk and return. Unit II Capital Budgeting Decision Meaning, Types, Decision Criterion, Calculation of Relevant Cash Flows, Methods of evaluation (Discounted cash flow methods and Non-discounted cash flow methods). Simple Problems on Capital Budgeting. Concept of cost of capital. Weighted average cost of capital. Unit III Financing Decision Basic sources of finance. Meaning of Capital Structure. Financial Leverage. EBIT-EPS Analysis. Simple problems on NI, NOI, and MM Hypothesis (without taxes). Unit IV Dividend Decision Theories (Walter, Gordon, MM Hypotheses), Determinants of dividend decisions. Stability of Dividend. Simple Problems on Dividend and Valuation of Firm. Unit V Working Capital management Concept and importance of working capital. Elements of Working Capital. Determinants of Working Capital. Simple Problems on estimation of working capital requirement. 161 Suggested Readings 1. Vanhorne, Financial Management and Policy, Prentice Hall, India (2003). 2. Pandey, I. M., Financial Management, Vikas Publications, (2005). 3. Khan, M.Y. and Jain, P. K. Financial Management, Tata McGraw Hill, (2005). 4. Rustagi, R.P., Fundamentals of Financial Management, Galgotia Publishers, New Delhi, (2006). 163 3rd Year 165 CHEMISTRY CH 301 INORGANIC AND PHYSICAL CHEMISTRY (3 Lectures per week) Unit I Transition Elements and Coordination Chemistry Transition elements General group trends with special reference to electronic configuration, variable valency, colour, magnetic and catalytic properties, ability to form complexes and stability of various oxidation states (Latimer diagram) for 3d-series. 6 Lanthanoides and actinodes : electronic configurations. Oxidation states, colour, spectral and magnetic properties, lanthanide contraction, separation of lanthanoides (ion exchange method only). 4 Chemistry of 3d metals:Chemistry (excluding metallurgy) of chromium, manganese, iron and cobalt in various oxidation states and their biological importance. 11 Coordination chemistry Valence bond Theory (VBT): Inner and outer orbital complexes of Cr, Fe, Co, Ni and Cu (coordination numbers 4 and 6). Structural and Steroisomerism in complexes with coordination numbers 4 and 6. Drawbacks of VBT. IUPAC system of Nomenclature. Hard and soft acid-base (HSAB) concept as applied to complexes. 8 Crystal field theory: Crystal field effect. Octahedral symmetry. Crystal field stabilization energy (CFSE). Crystal field effects for weak and strong fields. Tetrahedral symmetry. Factors affecting the magnitude of ?. Spectrochemical series. Comparison of CFSE for Oh and Td complexes. Tetragonal distortion of octahedral geometry. Jahn-Teller distortion. Square planar coordination. 10 166 Unit II Organometallic Compounds (6 L) Organometallic compounds Definition and classification based on nature of metal-carbon bond (ionic, s, p and multicentre bond). Structures of methyl lithium, Zeiss salt and ferrocene. EAN rule as applied to carbonyls. Preparation, structure, bonding and properties of mononuclear and polynuclear carbonyls. of 3d metals. p – acceptor behaviour of carbon monoxide. Synergic effect (VB approach). 6 Unit III Solid State & Molecular Symmetry (11 L) Solids Bravais lattices. Identification of lattice planes. Miller indices. X-ray diffraction. The Bragg Law. Types of crystals— molecular, covalent, metallic and ionic with examples. Characteristics of these crystals. Structures of NaCl, CsCl, ZnS & CaCl2. Point defects in ionic crystals. Colour centers and dislocations. 6 Molecular Symmetry Symmetry elements and symmetry operations: identity (E). rotation about an axis (Cn), improper rotation (Sn). Plane of symmetry and center of symmetry. Assignment of point groups for simple molecules. Important information from point groups of molecules. 5 UNIT IV CHEMICAL KINETICS & PHOTOCHEMISTRY (14 L) Chemical Kinetics Derivation of first and second order rate equations (both for equal and unequal concentrations of reactants) Half life time. Methods for determining the order of a reaction. Influence of temperature on reaction rate. Activation energy and its calculation from Arrhenius equation. Lindemann Theory of unimolecular reactions. Complex reactions such as consecutive reactions, parallel reactions and opposing reactions (with examples) and their differential rate equations only. Theories of Reaction Rates: Collision theory and Activated Complex theory of bimolecular reactions. Comparison of the two theories. 167 Introduction to Femtochemistry. Mechanism and kinetics of enzyme catalysed reactions— Michaelis- Menten equation. Effect of temperature on enzyme catalysis. 10 Photochemistry Absorption of light. Lambert-Beer law. Primary and secondary effects of light absorption, Laws of photochemistry, Quantum efficiency-Reasons for low and high quantum yields, Photoelectric cells. Phosphorescence and fluorescence. Jablonski diagram. Chemiluminescence. 4 168 CH 302 ORGANIC AND PHYSICAL CHEMISTRY (3 Lectures per week) Unit I Polynuclear, Hetero-Aromatic Compounds & Polymers (15 L) Polynuclear and Hetero-aromatic compounds Preparation and properties of the following compounds and important derivatives-Naphthalene (including structure elucidation). Anthracene, Pyrrole, Furan, Thiophene, Pyridine and Quinoline. 7 Polymers Definition and classification. Mechanism of polymerization (ionic, free radical and Ziegler-Natta catalyst). Preparation, properties and uses of the following polymers-nylons, polyesters, polyvinyl chloride, teflon, bakelite, urea and melamine-formaldehyde resins. Natural rubber (isolation, structure and vulcanization). Synthetic elastomers-buna-S, butyl rubber, polyurethane and foam. Use of additives in improving environmental degradability of vinyl polymers (polyethylene). Development of bio-degradable polymers-polylactic acid and polyhydroxybutyric acid. 8 Unit II Natural Products (20 L) Amino acids, Peptides and Proteins Natural and essential amino acids: Synthesis of simple amino acids by following methods- Amination of haloacids. Gabriel’s phthalimide, malonic ester and Erlenmeyer azlactone synthesis. Configuration of natural amino acids and their properties. Peptides: Primary structure determination by degradation, N-terminal (Edman and DNP method), C-terminal (hydrazinolysis) and hydrolysis of peptides. Synthesis of simple tripeptides only. Synthesis of peptides-by use of N-protecting groups. (t-butyloxycarbonyl and phthaloyl) C-activating groups, Merrifield solidphase synthesis. Proteins: Importance, primary, secondary, tertiary and quaternary structures (definition only). 10 169 Carbohydrates: Definition, classification and nomenclature. Determination of configuration of monosaccharides. Ascending and descending of monosaccharides series. Interconversion of aldoses and ketoses, Structure elucidation of glucose and fructose (open chain and cyclic), mutarotation. Structure of sucrose, starch and cellulose (excluding structure elucidation). Alkaloids: Definition and classification. Structure, synthesis and uses of Atropine. 10 Unit III Spectroscopy (10 L) Ultraviolet and Visible: Electromagnetic radiations, electronic transitions ? max, chromophore, auxochrome, batho and hypsochromic shifts. Application of electronic spectroscopy and Woodward rules for calculating ? max of conjugated dienes and a, ß - unsaturated carbonyl compounds. Colour and constitution. Infra red: IR radiations and types of molecular vibrations. Functional group and finger print region. Sampling in IR spectroscopy, IR spectra of alkanes, alkenes, alcohols (Inter and Intramolecular hydrogen bonding), aldehydes, ketones, carboxylic acids and their derivatives (effect of substitution on > C=O stretching absorptions). Unit IV Quantum Chemistry & Molecular Spectroscopy (16 L) Postulates of quantum mechanics. Discussion of observables and quantum mechanical operators. Writing the time independent. Schrödinger equation for different systems (e.g. particle in a box, rigid rotator, linear harmonic oscillator and hydrogen atom). Interpretation of wave function. What is spectroscopy? Importance of spectroscopy. Role of quantum mechanics in spectroscopy. Difference between atomic and molecular spectroscopy. Absorption and emission spectroscopy. Regions of the electromagnetic spectrum. Width and intensity of spectral lines. Born- Openheimer approximation. Separation of molecular energies into translational, rotational, vibrational and electronic components. Applications Translational motion: Schrödinger equation for a particle in one dimensional box and its results (solution not required). Quantisaiton of 170 the translational energy levels; properties of the solutions; Generalisation to three dimensions, concept of degeneracy. Rotational motion: Schrödinger equation of a rigid diatonic rotator and its results (solution not required). Quantisation of rotational energy levels. Microwave (pure rotational) spectra of diatomic molecules. Selection rules, Structural information from rotational spectra. Vibrational motion: Schrödinger equation for a linear harmonic oscillator and its results (solution not required). Brief discussion of results. Quantisation of vibrational energy levels. Infrared (Vibrational) Spectra of diatomic molecules. Selection rules. Structural information from vibrational spectra. Raman spectra: A brief introduction. Rotational Raman Spectra and Vibrational-Raman spectra. Structural information from Raman Spectra. Vibrations of polyatomic molecules. (e.g. CO2, H2O) (qualitative treatment), Normal modes of Vibration. Unit V Surface Chemistry & Polymers (9 L) Surface Chemistry : Adsorption by solids. Langmuir theory of adsorption of a gas on a solid. Langmuir adsorption isotherm. BET theory of multilayer adsorption of a gas on a solid. BET equation (derivation not required). Calculation of surface area of adsorbent from the BET equation. Types of adsorption isotherms. Adsorption chromatography. 4 Polymers: Different schemes of classification of polymers. Molar mass of polymers and its distribution- the number average and mass average molar masses. Methods of determining molar mass-osmotic pressure, sedimentation, viscosity and light scattering methods. Introduction to electrically conducting polymers. 5 171 CH 303 CHEMISTRY LABORATORY - II Note : Practical examination will include three exercises — one each out of the following physical, organic and inorganic chemistry experiments. 1. Determination of partition coefficient for iodine between water and carbon tetrachloride. 2. Construction of a phase diagram of a binary system (ureanaphthalene) by cooling curves method. 3. Study of the kinetics of the hydrolysis of methyl acetate in presence of hydrochloric acid using (i) initial rate method and (ii) integrated rate method. 4. Analysis of the given organic compounds containing only one of the following functional groups: Carboxylic acids, alcohols, phenols, aldehydes & ketones, carbohydrates (monosaccharides), acid amides, aromatic nitro compounds, aromatic primary amines. 5. Preparation of tetraamminecarbanatocobalt (III) nitrate and measurement of its conductivity. 6. (a) Preparation of potassium trioxalatoferrate (III) trihydrate and measurement of its conductivity. (b) Estimate the amount of iron present in the above complex or in a standard solution as Fe2O3 gravimetrically. 7. Estimation of the amount of nickel present in a given solution as Bis (dimethylglyoximato) nickel (II) gravimetrically. 8. Estimation of (i) Mg2- or (ii) Zn2- by complexometric titrations using EDTA. 9. Estimation of total hardness of a given sample of water by complexometric titration. 10. Determination of the composition of the Fe3+ -salicylic acid complex in solution by Job’s method. 172 Suggested Readings 1. James E. Huheey, Ellen Keiter and Richard Keiter: Inorganic Chemistry: Principles of Structure and Reactivity, Pearson Publication. 2. G.L. Miessler and Donald A. Tarr: Inorganic Chemistry, Pearson Publication. 3. J.D. Lee : A New Concise Inorganic Chemistry, E.L.B.S. 4. F.A. Cotton & G. Wilkinson: Basic Inorganic Chemistry, John Wiley & Sons. 5. I. L. Finar: Organic Chemistry (Vol. I & II). E.L.B.S. 6. John R. Dyer: Applications of Absorption Spectroscopy of Organic Compounds, Prentice Hall. 7. R.M. Silverstein, G.C. Bassler and T.C. Morrill: Spectroscopic Identification of Organic Compounds, John Wiley & Sons. 8. R.T. Morrison & R.N. Boyd: Organic Chemistry, Prentice Hall. 9. George Odian: Principles of Polymerization, Wiley-Interscience. 10. Peter Sykes: A Guide Book to Mechanism in Organic Chemistry, Orient Longman. 11. P.W. Atkins: Physical Chemistry, Oxford University Press. 12. G.W. Castellan: Physical Chemistry, Narosa Publishing House. 13. C.N. Banwell: Fundamentals of Molecular Spectroscopy. Tata McGraw Hill. Additional Reference Books 1. Dougles, McDaniel and Alexader: Concepts and Models in Inorganic Chemistry, John Wiley & Sons. 2. A.G. Sharpe: Inorganic Chemistry, Pearson Education. 3. F.A.Carey and R. J. Sundberg: Advanced Organic Chemistry, Plenum Publishers. 4. W.J. Moore, Physical Chemistry. Prentice-Hall. 5. G.M. Barrow, Physical Chemistry. Tata McGraw-Hill. 6. Donald A. McQuarrie : Quantum Chemistry. Oxford University Press. 173 PHYSICS PH 301 ELECTROMAGNETIC THEORY (Physical Sciences / Applied Physical Sciences) (70 Lectures) Electric and Magnetic field (10 L) Gauss’ law and its applications. Potential energy of a charge distribution, energy density in an electric field. Electric field in dielectric media. Magnetic induction due to a current carrying conductor. Force on a point charge in magnetic field. Hall effect. Divergence and curl of magnetic induction. Energy stored in magnetic field. Magnetic energy in terms of current and inductance. Magnetic force between two conductors. Magnetic field intensity and Ampere’s law. AC circuits (5 L) Kirchoff’s law. Mesh and node analysis of ac circuits. LCR circuit. Wheatstone’s bridge and its application in Wein bridge and Anderson bridge. Charge particle dynamics (6 L) Charged particle dynamics in uniform and time varying electric and magnetic field. Guiding centre approximation and drift motion-electric, curvature, gradient drifts. Maxwell’s equations (6 L) Conservation of charge. Modification of Ampere’s law. Maxwell’s equations in vacuum and inside matter. Boundary conditions. Electromagnetic waves (34 L) Wave equation, sinusoidal waves. Polarization of E.M. waves. Brewster’s angle. Description of linear, circular and elliptical polarization. Reflection and transmission. Poynting’s theorem, conservation of momentum. Electromagnetic waves in non-conducting media; monochromatic plane waves. Plane waves in conducting media. Skin depth. Wave propagation in unmagnetized ionized media — Plasma oscillation. Electron plasma waves, Ion acoustic waves and electromagnetic waves, Landau wave 174 damping (concept only). Waves in magnetized ionized media. Electrostatic and EM waves parallel and perpendicular to external constant magnetic field. Wave-guide (9 L) Total internal reflection. Critical angle. Optical fiber. Numerical aperture. Acceptance angle. Types of optical fibers (Definition only). Wave guides. Coaxial transmission line. Modes in rectangular waveguide. Energy flow. Qualitative idea of attenuation in waveguides. Electromagnetic fields and waves 2nd Ed., Paul Lorrain & Dale Corson, CBS Pub. & distributors India Engineering electromagnetics, Nathan Ida, Springer Electromagnetic waves, Shevgaonker, Tata McGraw-Hill Electromagnetics, Joseph A. Edminister, Schaum outline series, Tata McGraw- Hill Introduction to plasma physics and controlled fusion, Francis F. Chen, Springer 175 PH 302 MODERN PHYSICS (Physical Sciences / Applied Physical Sciences) (70 Lectures) Quantum Mechanics (17 L) Time dependent and time independent Schrodinger equation, Operators, expectation values. Requirements of a wave function. Probabilistic interpretation, Probability current. Solution of Schrodinger equation in one dimension: particle in a box, step potential, barrier penetration and tunneling, Squrare well, Bound states. Nuclear Energy (8 L) Binding energy. Nuclear fission and fusion. Fission reactor. Fusion energy in Sun, Controlled thermonuclear fusion. Lawson criteria magnetically confined system-mirrors and Tokomak. Inertially confined laser driven fusion. Physics of Materials (20 L) Amorphous and crystalline solids, Lattice translation vectors. Unit cell. Reciprocal lattice. Crystal diffraction: Bragg’s law, diffraction of X-rays. Lattice vibrations. Linear monoatomic and diatomic chains. Acoustical and optical phonons. Qualitative description of the phonon spectrum in solid. Brillouin zones. Dia-, para - and ferri - and ferromagnetic materials. Classical Langevin theory of dia- and paramagnetic domains. Quantum mechanical treatment of paramagnetism. Curie’s law, Weiss’s theory of ferromagnetism. Electric susceptibility, polarizability, Clausius-Mosotti equation. Classical theory of electronic polarizability. Elementary band theory of solids, Bloch theorem, Kronig-Penney model, effective mass of electron. Energy band diagram in Conductor, insulator & semiconductor. Hall effect. Super conductor, Meissner effect. Critical field. Type I & II superconductor. London equation. Penetration depth. 176 Laser (5 L) Working principle, thermal equilibrium of radiation, principle of detailed balance, Einstein’ A & B coefficients, population inversion, construction and working of He-Ne laser. Semiconductor laser. Energy bands and carrier distribution in semiconductors. Absorption and emission in a semiconductor. Electronics (10 L) UJT characteristics and relaxation oscillator, construction and working of FET. Comparision between CE, CB and CC configurations of BJT,CE amplifier. Static & dynamic load line. Biasing of a transistor circuit (fixed and self). Class A, B and C amplifier (definition). Principles of feedback in amplifiers. Negative and positive feedback. Barkhausen criteria. Phase shift oscillator. Modulation and detection-Basic concepts of amplitude, frequency and phase modulations and demodulation. Detailed circuit of CE amplitude modulator and diode detector. Atmospheric Physics (10 L) General structure of atmosphere-Hydrostatic and diffusive equilibrium, Vertical variation of physical parameters like temperature, wind, relative humidity, Stability in the different layers of atmosphere, absorption of solar radiation, Atmospheric Ozone, Ozone loss, Tropospheric ozone, Ozone depletion problem. Global warming. Aerosols, sources and classification of aerosols. Mie scattering. Radio Remote Sensing of the earth’s atmosphere, Probing of atmosphere using radars and lidars. Concepts of Modern Physics, Arthur Beiser, Tata McGraw-Hill Edition Theory & problems of Modern Phys., Gautreau & William, Schaum outline series, Tata McGraw-Hill Concepts in Space Science, R.R. Daniel, University Press Introduction to plasma physics and controlled fusion, Franis F. Chen, Springer Integrated electronics, Millman Halkias, Tata McGraw-Hill Principle of fundamental electronics, John D. Ryder, Prentice-Hall of India Introduction to Solid State Physics, Charles Kittel, John Wiley & Sons 177 PH 303 PHYSICS LABORATORY - II (Physical Sciences / Applied Physical Sciences) 1. Determination of Hall coefficient 2. Study of Elliptically polarized light 3. Polarization by simple reflection 4. Ultrasonic grating, determination of frequency 5. To study the PE Hysteresis loop of a ferroelectric crystal 6. Coefficient of Self inductance by ac bridge (Anderson bridge) 7. BH curve by using solenoid 8. Design of CE amplifier of desired gain 9. Design of Phase shift Oscillator 10. Study of UJT characteristics and relaxation oscillator 11. Amplitude modulation using CE Amplifier 12. Study of PLL IC and find out capture and lock range 13. Ionization potential of a gas 14. Design 4-bit asynchronous counter 15. To study the 4-bit shift register A Minimum of ten experiments are to be performed by each student. 178 MATHEMATICS MA 301 REAL ANALYSIS (4 Lectures per week plus tutorial) Total Marks 150 Internal Assessment : 38 Marks Examination 112 Marks Unit I : Real Sequences (30 L) 36 Finite and infinite sets, examples of countable and uncountable sets. Real line, bounded sets, suprema and infima, statement of order completeness property of R, Archimedean property of R, intervals. Concept of cluster points and statement of Bolzano Weierstrass’ theorem. Cauchy convergence criterion for sequences. Cauchy’s theorem on limits, order preservation and squeeze theorem, monotone sequences and their convergence. Unit II: Infinite Series (42 L) 48 Infinite series. Cauchy convergence criterion for series, positive term series, geometric series, comparison test, convergence of p-series, Root test, Ratio test, alternating series, Leibnitz’s test. Definition and examples of absolute and conditional convergence. Sequences and series of functions, Pointwise and uniform convergence. Mn-test, M-test, change or order of limits. Power Series: radius of convergence, Cauchy-Hadamard theorem, termby- term differentiation and integration of power series. Definition in terms of Power series and their properties of exp (x), sin (x), cos (x). Unit III: Calculus of several variables (42 L) 28 Limit and continuity for real valued functions on R2, differentiability of real valued functions on R2, directional derivatives and gradients for these functions. Schwarz theorem, Young’s Therorem, Taylor’s theorem for functions of two variables, Maxima and Minima of functions of two variables. 179 Recommended Books 1. T. M. Apostol, Calculus, Voulme-1, John Wiley and Sons (Asia) Pte Ltd., 2002. 2. R.G. Bartle and D. R Sherbert: Introduction to real analysis, John Wiley and Sons (Asia) Pte. Ltd., 2000. 3. E. Fischer, Intermediate Real Analysis, Springer Verlag, 1983. 4. K.A. Ross, Elementary Analysis — The Theory of Calculus Series— Undergraduate Texts in Mathematics, Springer Verlag, 2003. 5. Robert T. Smith, Roland B. Minton, Calculus, McGraw Hill International, Edition, 2006. 6. Robert C. Wrede, Murray Spiegel, Advanced Calculus, Second Edition, Schaum’s series, Tata McGraw-Hill, 2005. 180 MA 302 ANALYSIS, ALGEBRA AND MECHANICS (Four Lectures per week/also one Tutorial) Internal Assessment 38 marks Examination 112 marks Total Marks 150 Unit I : Analysis (30 L) 37 Riemann Integral, conditions of integrability, Integrability of Continuous and monotonic functions. Improper integrals, Convergence of Improper integrals, Absolute and conditional convergence of Improper Integrals. Beta, Gamma functions and their properties. Double integrals, repeated integrals, line integrals in R2,Statement and illustration of Green’s theorem. Fourier series of an integrable function on [-p, p], Fourier series expansion of piecewise monotonic functions on [-p, p]. Unit II : Linear Algebra (30 L) 37 Internal & external direct sums of vector spaces. Linear Transformations on real and complex vector spaces: definition, examples, kernel, range, rank, nullity, isomorphism theorems, invertible linear transformations (chatacterizations) Algebra of Linear transformations and matrix of a linear transformation Linear functional over real & complex vector spaces: definition and examples. Dual space, inner product spaces: definition, examples Unit III: Mechanics (30 L) 38 Conditions of equilibrium of a particle and of coplanar forces acting on a rigid Body, Laws of friction, Problems of equilibrium under forces including friction, Centre of gravity, Work and potential energy. 181 Velocity and acceleration of a particle along a curve: radial and transverse components (plane curve ), tangential and normal components (space curve), Newton’s Laws of motion, Simple harmonic motion, Simple Pendulum, Projectile Motion. Recommended Books Unit I 1. Frank Ayres, J. Elliott Mendelson, Calculus, Fourth Edition, Schaum series, Tata McGraw Hill, 2005. 2. R.G. Bartle and D.R. Sherbut; Introduction to real analysis, John Wiley and Sons (Asia) Pte. Ltd. 2000. 3. E. Fischer, Intermedial Real Analysis, Springer Verlag, 1983. 4. K. A. Ross, Elementary Analysis — The Theory of Calculus Series- Undergraduate Texts in Mathematics, Springer Verlag, 2003. Unit II 1. C.W. Curtis, Linear Algebra, an introductory approach, Springer- Verlag, 1991. 2. David M. Blotin, Linear algebra and Geometry, Cambridge Press, 1979. 3. Seymour Lipschutz, Linear Algebra, Schauss series, Tata McGraw Hill, 1989. Unit III 1. A.S. Ramsay, Statics, CBS Publishers and Distributors (Indian Reprint), 1998. 2. A.P. Roberts, Statics and Dynamics with background in Mathematics, Cambridge University Press, 2003. 3. J.L. Synge and B. A. Griffiths, Principles of Mechanics, McGraw Hill, 1970. 182 BOTANY AND ZOOLOGY (LIFE SCIENCES) LS 301 DEVELOPMENT BIOLOGY AND PHYSIOLOGY : PLANTS Plants are immobile and represent modular systems. Many structural and physiological adaptations expressed by plants under varied environmental conditions play a crucial role in their survivals. This course encompasses the basic understanding of all those developmental and physiological events during the life of a plant that give it the capacity to grow, synthesize food and defend itself and reproduce in a variety of ways. Unit I Developmental Biology Introduction and scope; significance of polarity. Unit II Meristems and derivatives Structural organization of shoot and root apices; vascular cambium and its derivates; periderm. Unit III Vascular elements Cytodifferentiation and functions of vascular elements. Unit IV Leaf initiation and development Ontogeny and function of stomata and trichomes. Unit V Structural organization of flower and flower initiation Initiation and differentiation of floral organs; mutations affecting floral differentiation; homeotic mutations affecting floral organ identity. Unit VI Anther Structure and development, microsporogenesis, pollen development, male sterility. Unit VII Ovule Structure and types; megasporogenesis; types of embryo sacs. 183 Unit VIII Fertilization Pollination, pollen-pistil interaction; double fertilization. Unit IX Seed development Types and functions of endosperm; embryogenesis; polymbryony and apomixis. Unit X Water Relations Absorption and transport, transpiration and significance. Unit XI Mineral nutrition Essential elements, criteria of essentiality, macro and micro nutrients and their role, physiological basis of mineral deficiency, role of mycorrhiza, ion antagonism. Unit XII Photosynthesis Pigments, role of accessory pigments, photochemistry of pigment excitation, photosystem I & II, reaction center, antenna system, Electron transport and mechanism of ATP synthesis, oxygen evolution, C 3 , C 4 , and CAM pathways of carbon fixation, photorespiration. Unit XIII Solute transport Transport of inorganic and organic components, transport pathways—xylem and phloem. Unit XIV Assimilation of nitrogen Nitrogen compounds utilized by plants, uptake and assimilation of ammonia, biological nitrogen fixation. UNIT XV Respiration Glycolysis, anaerobic respiration, tricarboxylic acid cycle, electron transport chain, cyanide resistant respiration and its significance, pentose phosphate pathway, salt respiration. Unit XVI Growth, development and differentiation Significance of polarity, photoperiodism vernilization, flowering, seed dormancy, causes and methods of overcoming seed dormancy, senescence, phytohormones— auxin, gibberelin, 184 cytokinin, abscisic acid, ethylene, polyamines, cystamine, brassinosteroids, jasmonic acid and their physiological response, application. Signal transduction-an overview, photosensors-phytocromes and cryptochromes. Suggested Readings Bhojwani, S.S. & Bhatnagar, S.P. (1999). Embryology of Angiosperms. 4th ed. Vikas Pub. House Pvt. Ltd., New Delhi. Bierhorst, D.W. (1971). Morphology of Vascular Plants. MacMillan Company Ltd. New York. Fahn, A. 1982. Plant Anatomy (3rd Edition). Pergamon Press, Oxford. Johri, B.M. (ed.). (1982). Experimental Embryology of Vascular Plants. Springer, Heidelberg. Hopkins, W.G. 1999. Introduction to Plant Physiology. John Wiley and sons, New York. Leopald, A.C. and Kriedemann, P.E. Plant Growth and Development. Tata McGraw Hill, New Delhi. Nelson, D.L. and Cox, M. M. 1993. Principles of Biochemistry. MacMillan Worth Publications. Salisbury, F.B. and Ross, C.W. 1993. Plant Physiology (2nd Edition) Wadsworth, USA. 185 LS 302 DEVELOPMENT BIOLOGY AND PHYSIOLOGY : ANIMALS Developmental Biology and Physiology have progressed tremendously in the past few decades. Development of an embryo is recognized as a manifestation of a morphogenetic potential of individual cells. And understanding of the fundamental principles of development would come from studying cellular structure and function. Physiology and functional histology constitute a dynamic area of study which emphases on the basic principles of body mechanism. Unit I Developmental Biology Introduction and scope of Embryology. Unit II Gametogenesis and fertilization Gametogenesis, types of eggs, fertilization, Parthenogenesis. Unit III Embryonic development Cleavage, blastulation, gastrulation in frog, chick and man, fate of germ layers, Formation of extra-embryonic membranes in chick and human Placenta (physiology and types). Unit IV Embryonic Induction Nature and action of organizer, tissue interactions, regional types and basis of induction. Unit V Post-embryonic morphogenesis Metamorphosis and regeneration. Unit VI Genes in development Role of genes in development, amniocentesis, stem cell culture and cloning, transfer of genes into animal oocytes, embryos and tissues, biosafety and ethical issues of cloning. Unit VII Gerontology & Teratology Growth, Ageing (concepts and model), Teratology: causes and examples. 186 Unit VIII Tissues & glands Epithelial tissue, Connective tissue, Muscular tissue, Nervous tissue and types of glands. Unit IX Nutrition and Digestion (Fueling body activities) Heterotrophic forms of nutrition, transport and mixing of food in the alimentary canal, secretory functions of alimentary tract, digestion and absorption in the gastro-intestinal tract, malfunction of GIT. Unit X Functioning of excitable tissues (membrane, nerve, muscle) Basic mechanism of transport across the membrane, membrane potential, action potential and its propagation, Synaptic and junctional transmission. Ultrastructure of the skeletal muscle fibre. Molecular mechanism of muscle contraction. Unit XI Maintenance of internal environment of the body Pulmonary ventilation, physiological principles of gaseous exchange transport of oxygen and carbon dioxide in the blood, regulation of respiration. Functional anatomy of kidney, formation of urine, control of extra-cellular fluid, osmolality and sodium concentration (counter-current mechanism). Role of anti diuretic hormone and aldosterone. Unit XII Cardiovascular system Circulating body fluids, blood haemostasis, the heart as a pump, origin and propagation of heart beat, cardiac cycle including ECG, blood pressure, and disorders of blood. Unit XIII Endocrine system and reproduction Physiology of human male and female reproduction. An overview of other endocrine organs and their hormones. 187 Suggested Readings Balinsky, B.I. (1981). Introduction to Embryology, 5th edition, Saunders College Publishers, Philadelphia, USA. Berril, N.J. and Carp, G. (1976). Developmental Biology, Tata- McGraw Hill, New Delhi. Gilbert, S.F. (2003) Developmental Biology, 7th edition. Sinauer Associates Inc. Publishers. USA. Guyton, A.C. and Hall, J.E. (2000). Textbook of Medical Physiology. 18th edition. Hercourt Asia PTE Ltd., W.B. Saudners Company. USA. Vander, A.J. Sherman, J.H. and Luciano, D.S. (2005). Human Physiology— The Mechanisms of Body Function. McGraw Hill Publishing Co., USA. 188 LS 303 ECOLOGY AND ENVIRONMENTAL MANAGEMENT An effort has been made in this paper to make the teaching of Ecology and Environmental Management more interactive and informative. Besides dealing with the fundamental aspects of population and community ecology, ecosystems and biomes, a section on Environmental Management has been included keeping in view the current global environmental concerns. This section deals not only with the physical and biological resources of the environment but also highlights topics like urbanization, waste management, disaster management and pollution control. Unit I Introduction to ecology Inter-relationships between the living world and environment; Biosphere and its components (Abiotic and biotic). Environmental concepts (Theory of tolerance, laws of limiting factors). Unit II Ecological adaptations Predation-types, predator-prey system, evolution and significance, functional and numerical response; Host parasite interactions, Social parasitism, symbiosis. Unit III Population Ecology Population attributes, Density, natality, mortality, age ratio, sex ratio, dispersal and dispersion of population, exponential and logistic growth, Verhulst-Pearl growth equation & ‘r’ and ‘k’ strategies, Hardy-Weinberg equilibrium, Genetic drift. Population interactions, Gause’s principle, and multidimensional niche concept. Unit IV Community and Ecosystem Community characteristics— organization and succession in different habitats. Bioenergetics and Biogeochemical cycles. Unit V Biogeography Bathymetric distribution, Geologic distribution, Phytogeography; Phytogeographic region of world, Major plant communities of 189 world, Vegetation of India with special reference to Delhi. Zoogeography: Barriers for dispersal, Means of Dispersal, Zoogeographic regions of world. Unit VI Bioresourse management Biodiversity and regional conservation strategies success stories with reference to India and sustainable utilization. Principles of wildlife management, wildlife sanctuaries, parks and biosphere reserves in India, Endangered and threatened species of plants and animals in India. Red Data Book, Germplasm banks. Unit VII Environmental issues Impact of urbanization and industrialization; Environmental Impact Assessment; Disaster management, Restoration of degraded ecosystems, Bioremediation, Biosafety. Unit VIII Policies and regulation Agencies, Legislation and International Conventions. Suggested Readings Smith, R.L. 1996. Ecology and Field Biology. Harper Collins College Publication. Odum, E.P. 1983. Basic Ecology. Saunders College Publications, Philadelphia. Chapman, J.L. and Reiss, M.J. 1992. Ecology: Principles and Applications. Cambridge University Press. Cunningham, W.P. and Saigo, B. W. (2005). Environmental Science, WCB McGraw Hill, New York. Miller, G.T. Jr. (2005). Environmental Science, 10th edition. Thomson/Brooke-Code. New Delhi. 190 LS 304 APPLIED BIOLOGY AND BIOTECHNOLOGY Human beings live in constant interaction with a vast variety of animals plants and microbes. Many species are useful to humans have been harnessed to meet human requirements. For those, which are harmful, causing deprivation of food or even inflicting disease, a perpetual fight is on in various ways. In addition, topics on basic techniques on biotechnology and applications of recombinant DNA technology in industry, medicine, development of vaccines, gene therapy, plant biotechnology and cloning of animals have been included. Unit I Useful Animals and their products Outlines of Apiculture and Sericulture, Edible and pearl oyster, increasing yield of poultry products, collection and uses of snake venom. Unit II Animals and Human diseases Transmission, pathogenicity and control of human diseases associated with various animals—Dengue, Japanese encephalitis, and Rabies, Epidemic typhus and Tuberculosis, Amoebiasis, Kala azar, Filariasis. Unit III Pests and Pest Control Life cycle and economical importance of following insect pest: Earias vitella, Heliothis armigera, Pyrilla perpusilla, Sitophilus oryzae, Trogoderma gramarium. Principles of insect control. Mechanical Physical , cultural, chemicals, Biological, genetic and Integrated pest management. Rodents pests and their control. Unit IV Human reproductive health and welfare Fertility and its Control, Assisted Reproductive Technology- IVF*, TET*, ZIFT*, GIFT*, ICSI*, PROST*, Contraception, Sexuality transmitted diseases, Demographic terms in family planning. (*IVF- In Vitro Fertilization, TET-Tubal Embryo Transfer, ZIFT-Zygote Intrafallopian Transfer, GIFT-Gamete intrafallopian Transfer, ICSI-Intra cytoplasmic Sperm Injection, PROST- Pronuclear stage transfer). 191 Unit V Plant resources utilization Food, fiber, fodder, timber, medicinal and aromatic plants, tobacco and rubber plants. Plant introduction and quarantine. Unit VI Resource development Role of agriculture, floriculture, forestry, organic farming. Unit VII Industrial microbiology Food, Pharmaceutical, enzymes industries. Unit VIII Introduction to Biotechnology Historical perspectives, Scope and importance, Commercial potential, Biotechnology in India and Global trends. Unit IX Recombinant DNA technology Cloning vectors- plasmids, cosmids, bacteriophages; restriction endonucleases, DNA ligases, transformation protocols for bacteria, plant and animal cells; construction and screening of genomic library, molecular analysis of DNA by Southern Blot Hybridization, PCR, DNA sequencing and microarrays. Unit X Applications of Recombinant DNA technology Genetically modified organism (GMOs) microbes, plants & animals and their importance: Recombinant vaccines. Gene therapy, DNA fingerprinting, single cell protein (SCP). Unit XI Bioinformatics Introduction, genetic data bases, sequence similarity and gene identification, Sequence annotation, Construction of phylogenetic trees, Computational tools for genome analysis. Unit XII Biotechnology and Society Public perception, Biopesticides, Biofertilizers, Biofuels and Biological Control, Patenting and IPR issues, Ethical and Biosafety issues. 192 Suggested Readings Pedigo, L.P. (1996). Entomology and Pest management, Prentice Hall, New Delhi. Kochhar, S. L. 1998. Economic Botany in the Tropics. Macmillan & Co. New Delhi Atwal, A.S. (2002). Agricultural Pests of India and South East Asia Kalyani Pub. New Delhi. Watson, J.D. (2003). Recombinant DNA, W.H.J. Freeman and Co., New York. Lewis, R. (1999). Human Genetics: Concepts and Applications. 3rd Edition. McGraw Hill, Dubuque, USA. Mount, D.W. (2004). Bioinformatics. Cold Spring Harbor Laboratory Press. USA. 193 LS 305 LAB Paper V— Developmental Biology and Physiology I: Plants 1. Structure of young anther wall, glandular and amoeboid tapetum, microsporogenesis, mature anther (permanent slides). W.m. pollen grains showing a few types of ornamentations and apertures, w.m. polyads, pollinia through fresh preparations/permanent slides/ photographs. 2. Pollen germination by hanging drop culture, calculation of percentage germination. 3. Study of monosporic (Polygonum) type of embryo sac development (permanent slides/photographs). 4. Study of mature embryo sac through electron micrographs showing egg apparatus. 5. Study of nuclear and cellular endosperm through permanent slides/ photographs. Dissection of developing seeds for endosperm showing haustoria. 6. Study of different stages of development of dicotyledonous embryo, mature dicot and monocot embryos through permanent slides. Dissection of developing seeds for embryos at various developmental stages. 7. Apical meristems (permanent slides/photograph). 8. Preparation of transverse section of maize/grass root and gram/ sunflower root. 9. Preparation of transverse sections of maize/grass root stem and sunflower stem (primary and secondary growth). 10. Preparation of transverse sections of monocot and dicot leaves. Epidermal peel showing stomata in Bryophyllum. Crinum and maize. 11. Determination of osmotic potential of plant cell sap by plasmolytic method. 12. Study of the effect of two environmental factors (light and wind) on transpiration by an excised twig/leaf. 13. Calculation of stomatal index and stomatal frequency of a mesophyte and a xerophyte. 194 14. Demonstration of the activity of enzymes (urease, catalase) from various plant sources. 15. Demonstration of dye reduction by isolasted chloroplasts under different light intensities. 16. Study of the ‘Law of Limiting factors’ (light intensity and bicarbonate concentration) Using Hydrilla. 17. Comparison of the rate of respiration in different parts of a plant. Demonstration Experiments 1. Phenomenon of bolting. 2. Inducing fruit ripening by ethylene. 3. Effect of auxins on rooting. Paper VI— Developmental Biology and Physiology II: Animals Study of developmental stages in frog-whole mounts and sections, cleavage stages, blastula, gastrula, neurula, tail bud tadpole. Study of whole mounts and sections of chick embryo at different stages, primitive streak, 24, 28, 33, 48, 72 and 96 hours. Study of Oogenesis and Spermatogenesis in Rat (Permanent Slides). Examination of sections of oesophagus, stomach, ileum, liver, pancreas, spleen, kidney, adrenal, thyroid of Mammals. Temporary mounts of striated muscle fibres and nerve cells. Determination of RBC count using haemocytometer. Determination of total and differential WBC count. Estimation of haemoglobin content in blood using haemoglobinometer. Demonstration of perfusion of the excised heart of frog. Detection of abnormal constituents in urine. Measurement of blood pressure using a sphygmomanometer. A visit to Poultry farm/Hatchery/Tissue culture laboratory/Animal breeding centers. 195 LS 306 LAB Paper VII — Ecology & Environmental Management Part-I 1. Study of following microclimatic variables in different locations: soil and air temperature, wind velocity, relative humidity and light intensity. 2. Determination of pH, field capacity, density and porosity of different soil samples, rapid test for soil texture. 3. Rapid field test of soils for carbonates, sulphates, chlorides, nitrates, organic matter and base deficiency. 4. Determination of minimal quadrate area by species area curve method; quantitative analysis of herbaceous vegetation for frequency and density. 5. Study of ecological adaptations of hydrophytes and xerophytes. Part-II 1. Study of an aquatic ecosystem-Measurement of total area, locality, temperature and turbidity/penetration of light, determination of pH, dissolved oxygen content (Winkler’s method) and dissolved carbon dioxide. 2. Study of biotic community with specials reference to plankton. Plotting of survivorship curves from hypothetical life table data. 3. Study of the ecological significance of phytoplankton, zooplankton, fishes, amphibians, reptiles, aves and mammals (2 representatives from each group). 4. Study of a few endangered reptiles, birds and masmmals of India. 5. A visit to National park/ Wildlife sanctuary/Waste management organization/ Mahatma Gandhi Institute for non-conventional energy sources ( Bakoli village, Gurgaon, and Sulabh International). 196 Paper VIII — Applied Biology & Biotechnology 1. Study of Apiculture, sericulture, and Aquaculture. 2. Study of protozoan, helminth parasites and arthropod vectors, associated with human diseases. 3. Study of the following through habitat sketches, temporary preparations, permanent slides, photographs, specimens, products, microchemical tests to bring out the economic importance: Cereals (wheat, rice), Legumes (soybean, groundnut), Sugars and Starches (sugarcane, potato), Spices (black pepper, clove, coriander, fennel), Beverages (tea, coffee), Oils and Fats (coconut, groundnut, mustard), Essential oil yielding plants (Rosa, Cymbopogon, Vetiveria, Eucalyptus and Santalum), Fiber-yielding plants (Gossypium, corchorus and Cocos), Woods (Tectona, Dalbergia, Pinus), Rubber (Hevea), Drug yielding plants (Cannabis, Papaver, Withania, Rauvolfia, Aloe), Nicotiana tabacum. 4. Study of insect pests of agricultural crops and stored grains (as listed in theory) and Insecticide dusting and spraying equipment. 5. Study of contraceptives in general use and acceptance. 6. Bacterial Staining (Gram Staining). 7. Study of genetic engineering techniques with help of photographs (PCR, Southern blot, GISH, FISH, DNA Fingerprinting). 8. Useful bioinformatics sites on internet, gene and protein databases, genome and organism specific databases, Multiple sequence alignment. 9. Construction of phylogenetic tree from DNA sequences from data provided. 197 COMPUTER SCIENCE CS 301 OPERATING SYSTEMS AND NETWORKS (3 Lectures/Week) 3 Hours, 100 Marks Operating Systems Introduction: Operating system functionalities, operating system classifications, operating system services, system calls and system programs, command line and graphical user interfaces. Processor Management: Program and process states, process scheduling algorithms, process synchronization. Memory Management: Partition based memory management, paging, segmentation, virtual memory. File Management: Introduction to I/O interfaces, file concepts, file operations, directory structure, file sharing and protection. Computer Networks Introduction: LAN, MAN, WAN internetworking, internet, intranet. ISO-OSI reference model: Features of physical, datalink/MAC layer, network, transport, session, presentation and application layer. TCP/IP reference model: TCP/IP protocol stack-features of IP and TCP protocol; application layer protocol-FTP, Telnet, SMTP, HTTP, Security. References 1. Abraham Silberchatz, Peter Baer Galvin, Greg Gagne, Operating System Concepts, John Wiley & Sons. 2. William Stallings, Operating Systems: Internals and Design Principles, Prentice Hall of India. 3. Andrew S. Tanenbaum, Computer Networks, Prentice Hall of India. 4. Douglas Comer, Computer Networks and Internets, Prentice Hall of India. 198 CS 302 SOFTWARE ENGINEERING AND DATABASES (3 Lectures/Week) 3 Hours, 100 Marks Software Engineering Introduction: Basic principles of software engineering, programming-in-thesmall vs. programming-in-the-large. Software Process: Software lifecycle, the waterfall model and variations, risk-driven approaches, introduction to evolutionary and prototyping approaches, system classifications. Project management: Relationship to lifecycle, project planning, project control, risk management, cost models, configuration management, quality assurance, metrics. Software requirements: Requirements analysis, requirements elicitation, analysis tools, requirements definition, requirements specification, static and dynamic specifications, requirements review. Software design: Design for reuse, design for change, design notations, design evaluation and validation. Implementation: Programming standards and procedures, modularity, data abstraction, static analysis, unit testing, integration testing, regression testing. Maintenance: Maintenance problem, planning for maintenance. Documentation: Quality, types, techniques for each stage. Databases Introduction: Basic concepts and ANSI architecture. Relational Model: Relational data model, relational algebra, SQL, functional dependencies, normal forms (up to BCNF), data modeling using EER diagrams, database design using these concepts. 199 References 1. Pankaj Jalote, An Integrated Approach to Software Engineering, Narosa Publishing House Pvt. Ltd., New Delhi. 2. Roger S. Pressman, Software Engineering: A Practitioner’s Approach, Tata McGraw Hill. 3. Silberschastz, Korth, Sudarshan, Database Systems Concepts, McGraw Hill. 4. Elmsan & Navathe, Fundamentals of database Systems, Pearson Education. 5. Raghu Ramakrishnan, et al, Databases Management Systems, McGraw Hill. 200 CS 303 LAB (BASED ON CS 301 AND CS 302) (Teaching 4 Lectures/per Week) Duration 4 Hours, Total 100 Marks 201 STATISTICS ST 301 STATISTICAL INFERENCE (75 Lectures) Sampling Distribution: Definitions of random sample, parameter and statistic, sampling distribution of a statistic, standard errors of sample mean, sample variance and sample proportion, Sampling distributions of Chi-square, t and F statistics, sampling distribution of sample mean and sample variance for normal distribution. Distribution of sample correlation coefficient r when P = 0. Tests of Significance: Null and alternative hypotheses, level of significance and probabilities of Type I and Type II errors, critical region and power of test. Large sample tests, Use of CLT for testing single proportion and difference of two proportions, single mean and difference of two means, standard deviation and difference of standard deviations, Tests of significance based on t, F and Chi-square distributions. Estimation: Parameter space, sample space, point estimation, requirement of a good estimator, Consistency, Unbiasedness, Efficiency, Sufficiency, Minimum variance unbiased estimators (statement only). Methods of estimation: Maximum Likelihood, Moments (without proof), Properties of Maximum Likelihood estimators (without proof). Interval estimation: Confidence intervals for the parameters of normal distribution, Confidence intervals for difference of means and for ratio of variances, Confidence intervals for binominal proportion and population correlation coefficient when population is normal, Large sample confidence intervals. Testing of Hypothesis: Statistical Hypotheses, Simple and composite Hypotheses. Test of Statistical Hypothesis, null and alternative Hypotheses. Critical region, Two kinds of errors, Level of significance and power of a test, Desiderata for a test of Hypothesis, MP tests and region, Neyman-Pearson Lemma, Critical regions for Simple Hypothesis for one parameter, Sequential probability ratio test, Determination of stopping bounds A and B, OC and ASN functions of SPRT for Normal and Binomial. Non-parametric tests, One sample and two sample sign test. Wald- Wolfowitz run test, Run test for Randomness, Median test, Wilcoxon- Mann-Whitney test (Derivation not required, give stress on examples). 202 Suggested Readings 1. Dudewicz, E.J. and Mishra, S.N. (1988): Modern Mathematical Statistics, John Wiley & Sons. 2. Goon, A.M. Gupta, M.K. and Dasgupta, B. (1985): An Outline of Statistical Theory, Vol. II, World Press, Calcutta. 3. Hogg, R.V. and Craig, A. (1999): Introduction to Mathematical Statistics, Prentice Hall. 4. Rohatgi, V.K. and Saleh, A.K. Md. E. (2005): An Introduction to Probability and Statistics, Second Edn., John Wiley & Sons. 203 ST 302 SAMPLE SURVEYS AND DESIGN OF EXPERIMENTS (Total Lectures: 75) Sample Surveys: Concepts of population and sample, Complete enumeration Vs. Sampling, Need for sampling, Principal and organizational aspects in the conduct of a Sample Survey, Properties of a good estimator, Sampling and non-sampling errors. Srswr & Srswor, determination of sample size, stratified random sampling, different allocations. Gain due to stratification, Construction of strata. Ratio and regression methods of estimation double sampling. Systematic sampling, Cluster sampling and two-stage sampling (with equal size cluster/ first-stage units). Linear Models, Estimability and BLUE, Method of least squares, Gauss Markoff theorem. Analysis of Variance and Covariance: Analysis of variance and covariance in one way and two way classified data with equal number of observations in each cell. Design of Experiments: Principles of experimentation, Uniformity trials, completely randomized, randomized block and Latin square designs, missing plot technique. 2n Factorial experiments — construction and analysis. Total and partial confounding, B.I.B. designs with intrablock analysis, relationships among its parameters, Incidence matrix, Symmetric B.I.B.D., Resolvable B.I.B. Design. Suggested Readings: 1. Cochran, W.G. (1977): Sampling Techniques, John Wiley & Sons. 2. Das, M.N. and Giri, N. C. ( 1986): Design and Analysis of Experiments, Wiley Eastern Ltd. 3. Kshirsagar, A.M. (1983): A Course in Linear Models, Marcel Dekker. 4. Montgomery, D.C. (2005): Design and Analysis of Experiments, Sixth Edition. John Wiley & Sons. 5. Sukhatme, P.V., Sukhatme, B.V., Sukhatme, S. and Asok, C. (1984). Sampling Theory of Surveys with Applications, lowa State University Press, lowa, USA. 204 ST 303 STATISTICS LABORATORY- II Handling of problems based on Tests of significance, Estimation, Testing of hypotheses, Non-parametric testing, Sample surveys, Linear models and Design of experiments as covered under ST. 301 and ST. 302; the practicals to be carried out on computer by developing programs in Python/C Language and using Statistical Software Packages. 205 OPERATIONAL RESEARCH OR. 301 RELIABILITY AND STATISTICAL QUALITY CONTROL (Three Lectures plus one tutorial per week) Total Marks : 150 Internal Assessment : 38 Marks Examination : 112 marks Duration : 3 Hours (a) Reliability: Basics of Reliability; Series, Parallel, Series-parallel, Parallel-series, Bridge and Standby Configurations. Life distributions: Exponential and Gamma Distributions. System Dependability Measures: Reliability, Availability, Mean-Time-to-System-Failure, Up- Time ratio. Reliability and Availability Models for One-Unit and Two Unit Systems (Steady State Solutions Only). Discrete Replacement Policies. Concepts of Preventive Maintenance, Corrective Maintenance and Age Replacement. (b) Statistical Quality Control : Elements of Statistical Quality Control, Basic Concepts of Statistical Process Control (SPC), SPC for Attribute Characteristics and Variable Characteristics; Process Capabilities, Acceptance Sampling Plan (Single and Double). Introduction to Six Sigma Quality. Elementary Concepts of ISO Certifications. Suggested Readings 1. Montgomery, D. C. Introduction to Statistical Quality Control, John Wiley & Sons, 2000. 2. Rau, G. John Optimization and Probability in Systems Engineering, Van Nostrand Reinhold Company,1970. 206 OR 302 FORECASTING AND CASE STUDIES (Three Lectures plus one tutorial per week) Total Marks 150 : 100 (Theory), Case Studies : 50 marks Theory Examination : 75 marks Internal Assessment : 25 marks Examination Duration : 3 hours (a) Forecasting Introduction to Business Forecasting, Introduction to Time Series and its components. Errors of Forecast. Time Series Models: Moving Averages, Exponential Smoothing, Smoothing Models for Seasonal Data, Ratio-to-Moving average Classical Decomposition Model. Forecasting using Simple Regression Models. Simulation and its Applications in Forecasting. (b) Case Studies The work on Case Study will start in the beginning of B.Sc. Part-III under approved supervisors from amongst the members of the staff and the case study report is to be submitted for evaluation before the beginning of the examination. It will carry 50 marks: Case Study Report - 30 marks Viva-voce - 10 marks Internal Assessment - 10 marks Suggested Readings 1. Armstrong, J. S. : Principles of Forecasting –A Handbook for Researchers and Practitioners (International Series in Operations Research & Management Science), Springer: 1, edition ( May, 2001). 2. Delurgio, S. A. : Forecasting Principles and Applications, McGraw- Hill, 1998. 3. Hanke, J. E. and Wichern, D. W. : Business Forecasting, 8th ed., Prentice Hall Inc., Upper Saddle River, New Jersey, 2005. 4. Makridakis, S., Wheelwright and : Forecasting: Methods Hyndman and Applications, 3rd ed., N. Y., John Wiley & Sons, 1998. 5. Montgomory, D. C., Johnson, L. A. and Gardiner, J.S. : Forecasting & Time Series Analysis, McGraw Hill, 1990. 207 ELECTRONICS EL 301 ELECTRONIC COMMUNICATION (70 Lectures) Total Marks : 100 Introduction (4 L) Block diagram of an electronic communication system, modulation and demodulation, electromagnetic spectrum band designations and applications. Waveform spectra and effect of filtering on complex signals. Analog Modulation (18 L) Amplitude Modulation : Frequency spectrum of AM waves, average power, average voltage, modulation index, AM-modulator circuits (collector and base modulation), balanced modulator, AM-demodulator (diode detector), single side band generation and detection. Angle Modulation : Frequency and phase modulation, frequency spectrum of FM waves, intersystem comparisons (FM and AM), generation of FM (direct and indirect methods), FM-demodulator (balanced slope and Foster-Seeley discriminator). Frequency division multiplexing (FDM). Transmitters and Receivers (4 L) Communication channels for AM and FM broadcast, AM and FM transmitter, tuned RF receiver, superheterodyne receiver. Pulse Analog Modulation (6 L) Sampling Theorem (with proof) and Nyquist Criterion. Pulse Modulation: pulse amplitude modulation (PAM), pulse width modulation (PWM) and pulse position modulation (PPM). Time division multiplexing (TDM). Digital Communication (16 L) Analog to Digital Conversion: Pulse code modulation (PCM). Digital Modulation and Demodulation Techniques (block diagrams); Amplitude Shift Keying (ASK), Frequency Shift Keying (FSK), Phase Shift Keying (PSK), Binary Phase Shift Keying (BPSK) and Quadrature Phase 208 Shift Keying (QPSK). Concept of Multiple Access techniques (FDMA, TDMA, CDMA). Modern Communication Systems (20 L) Data transmission: working principles of Modem and Fax. Mobile communication: introduction to GSM, cellular concept, multiple access for GSM, frequency allocation, concept of CDMA, working of CDMA systems (block diagram). Satellite communication: line of sight communication, geostationary orbit (derivation of orbital period), satellite antenna, satellite repeater block diagram (basic idea of various components), earth station block diagram (basic idea of various components). Optical communication; block diagram of an optical fiber communication link, the optical fiber (guidance, attenuation, dispersion and channel bandwidth), optical sources (LEDs and Laser diodes) and detectors (PIN and APD). Suggested Readings 1. Hsu H., Analog and Digital Communications, Schaum’s Outline Series, Tata McGraw-Hill, 2005. 2. Singh R.P. and Sapre S.D., Communication Systems; Analog and Digital, Tata McGraw-Hill, 2001. 3. Frenzel L.E. Communication Electronics, Principles and Applications, Tata McGraw-Hill, 2006. 4. Kennedy G. and Davis B., Electronic Communication Systems, Tata McGraw-Hill, 2005. 5. Palais J.C., Fiber Optic Communications, Pearson Education Asia, 2001. 6. Kolimbiris H., Digital Communication Systems, with Satellite and Fiber Optics Applications., Pearson Education Asia, 2001. 7. Schiller J., Mobile Communications, Pearson Education Asia, 2003. 209 EL 302 MICROPROCESSORS AND MICROCONTROLLERS (70 Lectures) Total Marks: 100 Introduction (12 L) Introduction to microprocessors and microcomputers, machine language, assembly language and high level language. Microprocessor architecture, types of buses, registers, memory mapping. Basic idea of INTEL 8085, 8086, 80186, 80286, 80386, 80486, Pentium processors. 8085 Microprocessor : pin-out diagram, classification of the signals, bus timings, types of machine cycles and their functioning, concepts in Memory interfacing and address decoding, peripheral mapped I/O, IN and OUT instruction, interfacing input and output devices, memory mapped I/O techniques, execution of memory related data transfer instruction. 8085 Programming (14 L) 8085 programming model: Accumulator, register and flags, instruction classification & programming concepts, stack and subroutine (CALL and RET statements), delay subroutines, introduction to transmission format, modes of data transfer. Interrupts: Maskable and non-maskable interrupts, RST (Restart), vectored interrupts & instructions (SIM & RIM). Peripheral Devices (20 L) Basic Input/Output, Address decoding, memory interfacing, peripheral mapped I/O, memory mapped I/O. Timing diagrams. 8155/8156 programmable device-l/O ports, control word, timer-mode 0,1,2,3. Handshake mode. 8279 Programmable Keyboard/display interface-hardware and functional description, keyboard can, display modes, software operation. 8255 Programmable Peripheral interface-functional description, operational modes. 210 8253 Programmable Interval Timer-modes of operation, internal organization and interfacing. 8259 Priority Interrupt Controller-interrupt and control logic section, read/write control logic section, vectoring data format. 8257 Direct Memory Access (DMA) controller-Block diagram, modes of operation, Read/Write logic block, control logic block, single byte transfer, types of modes. Interface Standards (4 L) Parallel interface; IEEE-488 Interface bus, GPIB signals and operation, S-100 bus standard. Serial interface: RS-232C, RS-422 and RS-423. Microcontrollers (20 L) Introduction to microcontrollers, advantages of microcontrollers. 8031/8051 Microcontroller; Architecture, register bank, flags, special function registers, I/O ports, timers, serial communication, interrupts, instruction set. Suggested Reading 1. Gaonker R. S., Microprocessor Architecture, Programming and Applications with the 8085, PRI-Penram International Publishing, 2000. 2. Sridhar P.K. and Ghosh P.R., 0000 to 8085: Introduction to Microprocessors, Prentice Hall of India,1995. 3. Ram B., Introduction to Microcomputer and Microprocessor, Dhanpat Rai and Sons, 1997. 4. Mazidi M.A. and Mazidi J.G., 8051 Microcontroller & Embedded Systems, Prentice Hall, 2006. 5. Calcut D., 8051 Microcontrollers, Elsevier, 2003. 6. Mathus A.P., Introduction to Microprocessors.TataMcGraw-Hill, 2004. 211 EL 303 ELECTRONICS LAB - II Total Marks: 100 Module-I Communication Electronics 1. Fourier Components of a Signal Waveform (2) 2. AM Modulation / Demodulation (2) 3. FM Modulation/ Demodulation (2) 4. Pulse Amplitude Modulation (PAM) (1) 5. Pulse Width Modulation (PWM) (1) 6. Radio Receivers (3) Module-II Microprocessors 7. 8-bit Addition, Subtraction, Multiplication and Division (3) 8. BCD Addition (1) 9. Arranging a given array in Ascending or Descending order (1) 10. Generation of A.P.Series, G.P. Series and Fibonacci series (3) 11. Decimal to Hexadecimal/ Hexadecimal to Decimal (1) 12. Generation of Clock (1) 13. Study of 8255. 8253 (3) 212 INDUSTRIAL CHEMISTRY IC 301 INDUSTRIAL CHEMICALS IN AGRICULTURE AND MEDICINE (75 Lectures) Total Marks: 100 1. Dyes: General introduction and classification with special reference to textile and edible dyes and fabric brighteners. Industrial preparation and uses of methyl orange, malachite green, indigo, bismark brown, alizarin. 2. Fertilizers and Pesticides: (a) Fertilizers : Different types of fertilizers, Manufacture of the following fertilizers: Urea, Ammonium nitrate, Calcium ammonium nitrate, Calcium cyanamide, Ammonium phosphates; Polyphosphate, Super phosphate, Double super phosphate, and Triple super phosphate, Compound and mixed fertilizers Potassium Chloride, Potassium sulphate. (b) Pesticides : General introduction to pesticides (natural and synthetic), benefits and adverse effects, changing concepts of pesticides, structure activity relationship, synthesis and technical manufacture and uses of representative pesticides in the following classes: Organochlorines (DDT, Gammexene, endosulphan); Organophosphates (Malathion, Parathion ) ; Carbamates (Carbofuran and carbaryl); Quinones ( Chloranil) , Anilides (Alachlor and Butachlor). 3. Drugs and Pharmaceuticals Drug discovery, design and development; Basic Retrosynthetic approach. Synthesis of the representative drugs of the following classes: analgesics agents, antipyretic agents, anti-inflammatory agents (Aspirin, paracetamol, lbuprofen); antibiotics (Chloramphenicol); antibacterial and antifungal agents (Sulphonamides; Sulphanethoxazol, Sulphacetamide, Trimethoprim); antiviral agents (Acyclovir), anticancer agents (Chlorambucil), cholinergics Methacholine), anticholinergics (Neostigmine), CNS 213 (Central Nervous System) agents (Phenobarbital, Diazepam),Cardiovascular (Glyceryl trinitrate) HIV-AIDS related drugs (AZT- Zidovudine). 4. Surface Coatings Objectives of coatings surfaces, preliminary treatment of surface, classification of surface coatings Paints and pigments , formulation composition and related properties. Oil paint, Vehicle, modified oils, Pigments, toners and lakes pigments, Fillers, Thinners, Enamels, emulsifying agents. Special paints (Heat retardant, Fire retardant, Eco-friendly paint, Plastic paint), Dyes, Wax polishing, Water and Oil paints, additives, Metallic coatings ( electrolytic and electroless), metal spraying and anodizing. 5. Battery Primary and secondary batteries, battery components and their role, Characteristics of Battery. Working of following batteries: Pbacid, Ni-Cd, Li-Battery, Solid state electrolyte battery. Fuel Cells and Solar cell. 6. Alloys Classification of alloys, Ferrous and Non Ferrous alloys, Specific properties of elements in alloys. Manufacture of Steel (removal of silicon decarbonization, demanganization, desulphurisation dephosphorisation) and surface treatment (argon treatment, heat treatment, nitriding, carburizing). Composition and properties of different types of steels. Suggested Readings 1. E. Stocchi, Industrial Chemistry , Vol -I, , Ellis Horwood Ltd. UK. 2. P.C. Jain, M. Jain, Engineering Chemistry, Dhanpat Rai & Sons, Delhi. 3. B.K. Sharma , Industrial Chemistry, Goel Publishing House, Meerut. 4. G.L. Patrick, Introduction to Medicinal Chemistry, Oxford University Press, UK. 5. Hakishan, V.K. Kapoor, Medicinal and Pharmaceutical Chemistry, Vallabh Prakashan, Pitampura, New Delhi. 6. R. Cremlyn, Pesticides, John Wiley. 7. William O. Foye , Thomas L., Lemke , David A. William , Principles of Medicinal Chemistry, B.I. Waverly Pvt Ltd. New Delhi. 214 IC 302 POLYMERS AND INSTRUMENTAL METHODS OF ANALYSIS (75 Lectures) Total Marks: 100 A. Polymers 1. Organic Polymers : Preparation, Properties, Classification, Structure property relationship (Thermoplastic and Thermosetting). Industrial manufacture of the monomers and the following polymers, Polystyrene, Polyacrylonitrile, Polymethacrylate, Polymethylmethacrylate, Polyethene, Polybutadiene, Polyvinylidene, Polycarbonates, Polyesters, Polyurethanes, Nylon (6,6:6,6:10), Phenolic polyesters, Polyamides, Polysulphones, Alkyds. Speciality Polymers (Electro-luminescent, Biopolymers, Conducting polymers), Rubbers (synthetic and natural) and their processing, Elastomers, Cellulosics, Natural and Synthetic fibers, fiber processing, anti wrinkle and flame retardant. Comparison of natural and synthetic polymers, relation between molecular structure and properties. Polymer Processing: Moulding, compounding, blending. Polymer designing, packaging, certification and process evaluation. Inorganic Polymers: Classification, preparation, properties and uses of boron containing polymers, phosphorus containing polymers, silicon containing polymers, Silicones (fluid, elastomers and resins) and sulphur containing polymers(SN)x. B. Quality Control and Instrumental Methods of Analysis 1. Purification and Separation: Sample preparation (isolation using a suitable solvent, extraction and separation), Solvent extraction. Distillation (simple, fractional and vacuum distillation), Crystallization. Chromatographic separation: High Performance Liquid Chromatography (HPLC), Gas Liquid Chromatography (G.L.C), Gas Chromatography (GC), Ion Exchange Chromatography. 2. Composition Analysis : Elemental analysis both qualitative and quantitative. 215 3. Physical Characterization: Strength, Viscosity, Rheological properties, Molecular weight. 4. Spectroscopic Methods : Ultraviolet Spectrophotometery (UV), Visible Spectro photometery, Infrared Spectrophotometery (IR), Nuclear Magnetic Resonance Spectrometer (NMR) and Electron Spin Resonance Spectrometer (ESR), Flame Photometry, Atomic Absorption Spectrometer (AAS), Induced Couple Plasma Spectrometer (ICP), Atomic Fluorescence Spectrometer. 5. Electro Analytical Techniques : Potentiometery, Voltametry, Polarography, Amperometry, Coulometry and Conductometry . 6. Thermal Methods of Analysis : Thermal Gravimetric Analysis (TGA), Differential Thermal Analysis (DTA), Differential Scanning Calorimeter (DSC), Thermal Mechanical Analysis (TMA). 7. STANDARDS: ISI, BTS, ISO, EURO, ASTM. Suggested Readings 1. K.J. Saunders, Organic Polymer Chemistry ,Chapmann & Hall, London. 2. P.J. Flory, Principles of Polymer Chemistry, Cornell University Press, NY. 3. G. Odian, Principles of Polymerization, John Wiley & Sons Inc, NY. 4. James E. Mark, Hary Allcock, Robert West, Inorganic Polymers, Prentice Hall Englewood Cliffs, NY, 5. H.H. Willard, L.L. Merrit, J.A. Dean, F. A. Settle Instrumental Methods of Chemical Analysis ; Wadsworth Publishing Company, California. 6. G. D. Christian, Analytical Chemistry, John Wiley, NY. 7. S.M. Khopkar, Basic Concepts of Analytical Chemistry,Wiley Eastern Ltd, New Delhi. 216 IC 303 INDUSTRIAL CHEMISTRY LAB-II Total Marks 100 1. Estimation of phosphoric acid in beverages 2. Analysis of (Cu, Ni); (Cu, Zn ) in alloy or synthetic samples. 3. Analysis of Cement. 4. Preparation of Malachite Green. 5. Preparation of Methyl Orange. 6. Preparation of Maleic Anhydride. 7. Preparation of Caprolactum. 8. Preparation of Polystyrene. 9. Preparation of Poly Methyl Methacrylate. 10. Preparation of Hexamethylenediamine and Adipic acid. 11. Molecular weight determination of a polymer. 12. Estimation of amino acid. 13. Estimation of amino group. 14. Determination of composition of dolomite (by complexometric titration). 15. Electroless metallic coatings on ceramic and plastic material. 16. Thermal Characterization of the following. (Demonstration exercise) (i) Dolomite (for percentage composition by TGA) (ii) Polystyrene (for glass transition temperature by DTA) 17. Demonstration or class exercises on the use of IR, Mass, UV and NMR. spectra (Demonstration exercise). 18. Determination of free acidity in ammonium sulphate fertilizer. 19. Estimation of Calcium in Calcium ammonium nitrate fertilizer. 20. Estimation of phosphoric acid in superphosphate fertilizer. 21. Industrial project*. * Every student would be required to undergo practical training in a chemical industry for a period of 6-8 weeks and submit a report based on the training. 217 ANALYTICAL CHEMISTRY AC 301 SEPARATION METHODS IN ANALYTICAL CHEMISTRY (Total Lectures : 70) Total Marks : 100 A Chromatography: Classification of chromatographic methods: Principles of differential migration, description of the chromatographic process, distribution coefficients, modes of chromatography, performance of column chromatography Chromatography—theory and practice : Introduction, the chromatography (elution time and volume), capacity factor, column efficiency and resolution, sample preparation. Techniques of paper chromatography : experimental modifications, various modes of development, nature of the paper, detection of spots, retardation factors, factors that affect the reproducibility of Rf values (due to paper, solvent system, sample, development procedure), selection of solvent. Quantitative analysis, applications. Thin layer chromatography : stationary phase, adsorbents, liquid phase supports, plate preparation, mobile phase, sample application, development, saturation of chamber, detection of spot. Fro values (effect of adsorbent, solvent, solute, development process), quantitative analysis, applications. Column chromatography 1. General : Columns, matrix materials, stationary phase, column packing, application of sample, column development and sample elution, detectors and fraction collectors, applications. 2. High performance liquid chromatography: Principle, column, matrices and stationary phases, column packing, mobile, phase and pumps, application of sample, detectors, applications. 3. Adsorption chromatography: Principle, adsorbents, solvents, nature 218 of solute, operating parameters, retention volumes and times, applications. 4. Liquid-liquid partion chromatography: Principle, normal phase chromatography reversed-phase liquid chromatography, ion-pair reversed phase liquid chromatography, chiral chromatography, counter-current chromatography, applications. 5. Ion-exchange chromatography: Principle, ion exchangers, ionexchange equilibria, ion-exchange resin selectivity, column operations (column development, detection of solute bands), factors affecting retention volumes, applications. 6. Gel chromatography: Principle, types of gels, separation by gel chromatography, applications. 7. Affinity chromatography: Principle, materials, selection and attachment of ligand, practical procedure, applications. 8. Gas-liquid chromatography : Apparatus and materials, preparation and application of samples, separation conditions, detectors, applications. B Electophoretic techniques Principle, apparatus, support media (paper, cellulose acetate membranes, gels), SDS-PAGE, native gels, gradient gels, isoelectric focusing, 2D-PAGE, continuous flow electrophoresis, detection, estimation and recovery of proteins in gels, western blotting, electrophoresis of nucleic acids, capillary electrophoresis. C Solvent Extraction Distribution Equilibria, The distribution law, determination of Kd the distribution ratio. The dissociation affect, the association affect (Benzoic acid in water and benzene) and the complexation effect (potassium iodide-iodine in water and chloroform). Methods of Extraction, Batch extraction, continuous extraction and counter-current distribution. 219 Suggested Readings 1. J. Mendham, R.C. Deny, J.D. Barner and MJK Thomas, Vogel’s Textbook of Quantitative Chemical Analysis, Pearson Education, New Delhi. 2. D. A. Skoog, F.J. Holler and T. A. Nieman, Principles of Instrumental Analysis, Thomson Asia Pvt. Ltd. Singapore. 3. F.W. Fifeld and D. Kealy, Principles & Practice of Analytical Chemistry, Oxford, Blackwell Science. 4. O. Mikes, R.A. Chalmer, Laboratory Handbook of Chromatographic and Allied Methods, Elles Harwood Ltd. London. 5. R.V.Ditts, Analytical Chemistry-Methods of Separation. 220 AC 302 INSTRUMENTAL METHODS OF ANALYSIS (70 Lectures) Total Marks : 100 A. Spectroscopic Methods of Analysis 1. An Introduction to spectroscopic methods of analysis: Properties of electromagnetic radiations. The Electromagnetic spectrum Emission spectra, Absorption spectra: Atomic, IR, UV and visible absorptions: Terms used, To Fluorescence and phosphorescence. 2. UV and Visible Spectrophotometry: Lambert-beer’s law, Principles, instrumentation, single/double beam instrument, Applications, correlation of spectra with molecular structure, Quantitative Analysis. 3. IR Spectrophotometry: Basic principles, instrumentation, correlation of spectra with molecular structure, Quantitative applications. 4. Flame Photometry: Theoretical principles, Emission spectra, instrumentation, single/double beem instruments, experimental procedure, applications. 5. Atomic Spectroscopy: Types, atomizer, Atomic absorption and emission spectroscopy: Theory and applications. 6. Polarimetry : Theory, instrumentation, experimental procedure and applications. 7. NMR Spectroscopy : Principles, Instrumentation, Factors affecting chemical shifts, spin-coupling application. B. Radiochemical Method of Analysis (a) Radio isotope dilution method (b) Radio immuno assay 221 C. Thermal Method of Analysis Principle, instrumentation and application of thermogravimetric analysis (TGA), particular emphasis of calcium-oxalate D. Analytical Biochemistry (a) Carbohydrates—Structure and properties (b) Lipids—Structure, dassification, isolation and function (c) Protein — Structure, classification, isolation characterization and functions. (d) Blood chemistry — Composition, coagulation collection of blood samples, blood sugar, blood urea, creatine, blood cholesterol, triglyceride, blood billurubin, blood protein. (e) Urine Chemistry— Collection of samples, composition of normal and pathological urine, Estimation of sugar and albumin. E. Role of computers and Microprocessors in Analytical Chemistry Suggested Readings 1. H. Varley, Alan H. Gowenlock and Maurice Bell, Practical Clinical Bio-chemistry. 2. T.G. Cooper, Tool of Bio-Chemistry, John Wiley & Sons, Ltd. 3. D.A. Skoog, F.J. Holler and T.A. Nieman, Principles of Instrumental Analysis, Thomon Asia Pvt. Ltd. Singapore. 4. Brain Smith, Infra Red spectral interpretation : A Systematic Approach 222 AC 303 ANALYTICAL CHEMISTRY LAB-II Total Marks: 100 1. Determination of Exchange capacity of cation exchange resin and anion exchange resin. 2. Separation of organic acid by ion exchange chromatography. 3. Separation of amino acids from organic acids by ionexchange chromatography. 4. Solvent extraction of Nickel with DMG from a mixture of Nickel and Cobalt 5. Solvent Extraction of Zirconium with Amberclite LA-1 separation from a mixture of iron and gallium. 6. Determination of pKa, values of indicator using spectrophotometry. 7. Structural characterization of compounds by Infra-Red spectroscopy. 8. Temperature Dependent degradation of Calcium oxalate using TGA 9. Determination of dissolved oxygen in water 10. Determination of Chemical Oxygen Demand (COD) 11. Determination of Biological Oxygen Demand (BOD) 12. Identification and Estimation of the following :- (a) Carbohydrates - Qualitative and Quantitative Determination of Cholesterol by Liebermann-Burechard methods. (b) Isolation of Protein and Determination of Protein by the biuret method. 223 ENVIRONMENTAL SCIENCE ES 301 ENVIRONMENTAL CONCERNS AND HEALTH (72 Lectures) Total Marks; 100 Unit I Pollution biology Types, sources (external loads) of pollutants Impact on organisms, agriculture, forests and wildlife Bio-monitoring. Bio-indicators and Environmental Monitoring. Case studies (Ganga Action Plan: Introduction of unleaded petrol and CNG in Delhi). Unit II Climate change El Nino, Global warming, Acid rain. Ozone layer depletion, Nuclear accidents and Holocausts — case studies. Impact on agriculture, forests, wildlife and human health Assessment and mitigation strategies. Unit III Waste management Types of wastes Disposal and management strategies Modem biotechnological approaches Recycling Wasteland reclaimation, Consumerism and Waste products. Unit IV Environmental toxicology Classification of toxic compounds, Acute, Subacute and Chronic toxicity. Statistical concepts of LD50 Dose effect and Dose Response Relationship. Bioaccumulation and Biomagnification of Toxic compounds. Influence of Ecological factors on the effects of toxicity, Toxicily threshhold limits. 224 Unit V Health risks of environmental pollutants Health Risks from Gases/Particulates, Heavy Metals (Cadmium, Mercury, Arsenic and Lead), Pesticides and Radiation. Occupational and Environmental Health Biotransformation of Xenobiotics: Phase I and Phase II Reactions, Role of Cytochrome P 450, Activation/Detoxification, Excretion, Carcinogenicity, Mutagenicity and Teratogenicity. Ubtianization stress and health. Unit VI Biosafety Genetically modified organisms and biosafety assessment Species introduction Species invasion. Policies and Measures (in reference to India) Cartagena protocol Intellectual Property Rights Suggested Readings 1. R. Rajagopalam (2005). Environmental Studies: “From Crisis to Cure” Oxford University Press. 2. Cunningham, William P. and Barbara Woodworth Saigo (1995). Environmental Sciences. A Global Concern. 3rd Edition. Boston. Wmc, Brown Publishers. 3. Sethi. I. Sethi M.S. and lqbal S.A. (2004). Environmental Pollution, Causes, Effects and Control. Commonwealth Publishers, New Delhi. 4. Raghunathan, Meena and Pandya (1999). The Green Reader: An Introduction to Environmental Concerns and Issues. Ahmedabad Centre For Environmental Education. 5. Miller G.T. (Jr.) (2002) Living in the Environment — Principles, Connections and Solutions. 12th Edition. Thomson Learning, Inc. 6. Jjemba, P.K. (2004). Environmental Microbiology — Principles and Applications. Science Publishers. Inc. 225 ES 302 ENVIRONMENTAL PROTECTION AND MANAGEMENT (72 Lectures) Total Marks : 100 Unit I Environmental Policies and Regulations Environment Protection — Basic concepts of Environmental Policies of India (Article 48A, Article 51A and Article 21 A of Constitution of India) Environmental Laws — The Water Act, 1974; Air Act, 1981; Environment (Protection) Act, 1986; Forest (Conservation) Act, 1980; Indian Forest Act, 1982; Wildlife (Protection) Act, 1972; Motor Vehicles Act, 1988. Biodiversitv Act. International Conventions — Stockholm Declaration, 1972; Ramsar Convention; World Heritage Convention; Kyoto Protocol; Rio Summit (Earth Summit); Johannesberg Summit, 2002. Montreal Protocol. Emironmentnl Certificate Systems ISO 14001 Issues involved in enforcement of Environmental legislations, Public Awareness. Unit II Remote Sensing Principles of Remote Sensing; Application in Water Resources Management, Land Use Planning, Mining, Landslide and Earthquake damage assessment. Unit III Environmental Impact Assessment Introduction, methodologies, project planning and implementation, green belts, role of GIS in risk assessment and mitigation measures, review and decision making, compensatory actions: Case studies- oil refineries and petrochemicals, tourism- coastal zone development. Unit IV Environmental Management Principles of air, water noise management. Management- issues and 226 practices (with case studies); Hazardous Waste Rules, 1989; Solid waste management-role of microbes in waste treatment, Strategies and regulations, Hazardous Waste Rules, 1989; Hazardous Chemical Rules, 1989: Biomedical Waste Rules, 1998. ISO Management: role of national and international organizations. Waste treatment, Bioremediation, IPM. Organic Fanning. Biological Control of Pests. Unit V Disasters Management Introduction, Natural disasters (case studies— Gujarat earthquake, Tsunamis 2004; Industrial disasters (case studies- Bhopal Tragedy. Chemobyl): Factories Act: Public Liability Act. Occupational Health. Unit VI Society and Environment Concept of eco-cities (with reference to India), Social and Civil Society movements (case studies: National— Tehri Dam. Chipko movement. APCO movement; International — WBCSD), Environmental Economics and Politics. Indian concerns. Judicial Activism, Public Interest Litigation. Suggested Readings 1. Aslopp, Seal and Gaylarde (2004). Introduction to Biodeterioration. Cambridge University Press. 2. Fingerman and Nagabhushnam (2005) Bioremediation — Aquatic and Terrestrial Ecosystems, Science Publishers, Inc. 3. Mohapatra, P.K. (2006) Textbook of Environmental Biotechnology. I.K.. International Publishing House Pvt Ltd. 4. Divan, Shyam and Rosencranz (2001). Environmental Law and Policy in India. 2nd Edition. Oxford University Press. 5. Wright Richard T. and Bernard J. Nebel (2004). Environmental Science : Towards a Sustainable Future. 8th Edition, Indian Reprint. Printice Hall of India. 227 ES 303 ENVIRONMENTAL SCIENCE LAB-II Total Marks: 100 1. Water analysis: (college pond, polluted and distilled water samples) (a) Study of pH and conductivity (b) Measurement of chloride, sulphate and salinity of water samples by simple titration method. (AgNO3 and potassium chromate) (c) Estimation of total alkalinity of water samples (CO3, HCO3) using double titration method. (d) Measurement of dissolved oxygen content and correlate the BOD with animal and plant diversity (Winkles method). (e) Measurement of dissolved CO2. (f) Measurement of COD in water samples. (g) Study in detail the various symptoms of (human health) diseases caused due to air and water pollution (at least two diseases in each category). (h) Estimation of E. coli in waste water. 2. Estimation of SPM in air samples. 3. Some common eco-toxicity tests (microbial). 4. Study of some of the common bio-indicators of pollution. 5. Determination of LD50/LC50 values from the data provided. 6. A demonstration of role of microbes in adsorption of contaminants/ heavy metals (Simple experiments can be framed). 7. Project report on selected case studies. (a) Natural disasters (b) River valley projects (c) Mining 8. Project report — Waste management/recycling 9. Manual interpretation of remote sensing data. 10. Visits: Polluted sites, banks of rivers. 228 BIOLOGY BIO 301 CELL AND MOLECULAR BIOLOGY AND DEVELOPMENT BIOLOGY (75 Lectures) Total Marks: 100 Unit I The Cell A brief introduction, cell theory, cell cycle and cell division. Unit II Cell Organelles Cell wall, cell membrane, organelles - mitochondria, chloroplast, nucleus, ribosomes, ER, golgi bodies, microbodies, lysosomes and perioxisomes. Unit III Cytoskeleton Microtubules, cilia and flagella, microfilaments. Unit IV Biomolecules Carbohydrates: Structure and functional significance of monodi- and polysaccharides; Lipids: structure, nomenclature, and functional significance of fatty acids, triglycerides, phospholipids, glycolipids and steroids, lipid peroxidation and role of antioxidants; Amino acids and Proteins: structure and general properties, role of chaperones in protein conformation (physiology of important peptides and proteins), Nucleic acids — DNA and RNA types and structure. Unit V Metabolism Carbohydrate metabolism: glycolysis, citric acid cycle, pentose phosphate patheway, gluconeogenesis; Lipids metabolism: beta oxidation of fatty acids, ketogenesis; Protein metabolism: Overview of protein degradation, catabolism of amino acids, transamination, oxidative deamination; Urea cycle, Intermediary metabolism: Inter-relationship of carbohydrates, lipid and protein metabolism. Unit VI Enzymes Nomenclature, classification, kinetics, mechanisms of action, inhibition. 229 Unit VII Molecular Biology DNA Replication; mechanism of DNA replication, inhibitors of DNA replication; Genetic Code: central dogma, nature of genetic code, mechanism of transcription and translation in protein synthesis; Regulation of Gene Expression: inducible and repressible systems, positive and negative controls, DNA methylation. Unit VIII Developmental Biology (Animals) Introduction and scope of Embryology; Gametogenesis and fertilization: types of eggs, fertilization, Parthenogenesis; Embryonic Development: Cleavage, blastulation, gastrulation in frog, chick and man, fate of germ layers, formation of extraembryonic membranes in chick and human Placenta (physiology and types); Post embryonic morphogenesis: Metamorphosis and regeneration; Genes in development: amniocentesis; Gerantology and Teratology: growth, ageing (concept and model) Teratology: causes and examples. Unit IX Developmental Biology (Plants) Introduction and scope, significance of polarity; Meristems and derivatives: vascular cambium and its derivatives, periderm; Vascular elements: Cytodifferentiation and functions of vascular elements; Structural organization of flower and mutations affecting floral differentiation; Anther: structure and development, microsporogenesis, pollen development; Ovule: structure and types, megasporogenesis, types of embryo sacs; Fertilization: pollination, pollen- pistil interaction, double fertilization; Seed development: types and functions of endosperm, embryogenesis, polyembryony and apomixis. Suggested Readings 1. Becker, W.M. Rees, J.K.B. and Poenine, M.F. (2002) The world of the cell. Benjamin/Cummings Publishing Company, New York and London. 2. Bhojwani, S.S. & Bhatnagar, S.P. (1999) Embryology of Angiosperms. 4th ed. Vikas Publ. House Pvt. Ltd., New Delhi. 3. Bruce, A. et al. (2002) Molecular Biology of the Cell. Garland Publishing Company, New York and London. 230 4. Davenport. An Outline of Animal Development, Addison-Wesley. 5. De Robertis, E.D.P. and De Robertis, E.M.F. Jr. (2002) Cell and Molecular Biology. Infomed Ltd., Hong Kong. 6. Gilbert, S.F. (1991) Developmental Biology. Sinauer Associates Inc. Publishers. 7. Hames, B.D. Hopper, N.M. and Hougton, J.D. (1998) Instant notes in Biochemistry. Viva Books Pvt. Ltd. 8. Karp, B. (2002) Cell and Molecular Biology. 3rd Edition. John Wiley and Sons, Inc., New York. 9. Lehninger, A.L. Nelson, D.K. and Cox, M.M. (1993) Principles of Biochemistry. CBS Publishers and Distributors. 10. Leopald, A.C. and Kriedemann, P.E. Plant Growth and Development. Tata McGraw Hill, New Delhi. 11. Oppenheimer, S.B. (1981) Introduction to Embryology. Allyn and Bacon. Sussman Animal Growth and developmental. Prentice Hall. 12. Stryer, L. (1995) Biochemistry. 4th ed. W.H. Freeman. 231 BIO 302 GENETICS, BIOTECHNOLOGY AND IMMUNOLOGY (75 Lectures) Total Marks: 100 Unit I Genetics (a) Transmission Genetics — Mendel’s laws of inheritance, allelic and non-allelic interactions, modified dihybrid ratios, polygenic inheritance, multiple alleles, extranuclear inheritance. (b) Physical and Molecular Organization of Genetic Material — chromosomes, chromosome morphology, karyotype, idiogram, polytene and lampbrush chromosomes, nucleosome, DNA/RNA as genetic material, Watson and Crick’s model, DNA forms (right handed and left handed), RNA types. (c) Genome organization — prokaryotic and eukaryotic genomes, gene structure, split and overlapping genes, gene sequencing, cDNA, satellite DNA, repetitive DNA, genome wide sequences, physical mapping, functional genomic. (d) Mutations — spontaneous and induced mutations, mechanism of mutation, genomic mutations (aneuploidy, eupolyploidy), chromosomal aberrations. (e) Linkage and Crossing Over — complete and incomplete linkage, two-point and three-point test cross, gene mapping, cytological basis of crossing over, Molecular basis of recombination: Holliday model, role of rec gene; sex-linked inheritance. Unit II Biotechnology (a) Recombinant DNA Technology — cloning vectors (plasmids, cosmids, bacteriophages), restriction endonucleases, DNA ligases, transformation protocols, gene constructs and screening of genomic library. (b) Genetic Engineering Techniques — PCR, Southern and Northern Blotting, DNA finger printing, RFLP, RAPD, REMI, stem cell research. 232 (c) Applications of Biotechnology — GM plants, resistance to pathogens, pests, stress tolerance; transgenic animals for generation of medicines, hormones, vaccines; microbial and industrial biotechnology for production of antibiotics, alcohol, single cell proteins, enzymes and other organic compounds, gene therapy, biomass production, metabolomics. (d) Ethics and Biosafety — public perception of biotechnology, intellectual property rights, patenting, ethical and biosafety issues. Unit III Immunology (a) Overview of immune system — innate, acquired immunity. (b) Generation of immune response — Antigens, immunogens and haptens, factors influencing immunogenicity, recognition of antigens, properties of B-cell and T-cell epitopes, antigenantibody interactions. (c) Immune effector mechanisms — Cytokines, complement system, hypersensitive reactions. (d) Immune system in health and disease — vaccines, autoimmunity, AIDS, diagnostic tools. Suggested Readings 1. Benjamin, P.A.B. (2002) Genetics: A Conceptual Approach. W.H. Freeman and Co. New York. 2. Brown, T.A. Genome. John Wiley & Sons (Asia) PTE Ltd. 3. Brown, T.D. (1999) Gene cloning and DNA analysis. Blackwell Science. 4. Hartl, D.L. and E.W. Jones. (1998) Genetics: Principles and Analysis. John and Bartlett, USA. 5. Richard, A.G. Kindt, T.J., Osborne, B.A. and Rodwell, V.W. (2003) lmmunology W.H. Freeman and Co. New York. 6. Roitt, 1. M. (2001) Essential Immunology. Blackwell Scientific Publications. 7. Russel, P.J. (1998) Genetics. The Benjamin/Cummings Publishing Co. Inc., USA. 233 BIO 303 BIOLOGY LAB - II Total Marks : 100 I. Cell & Molecular Biology and Developmental Biology Marks: 50 Unit I Cell & Molecular Biology 1. Cell structure — prokaryotic/eukaryotic cells, cell organelles through photomicrographs/electron micrographs. 2. Cytochemical demonstration of Nucleic Acids, Proteins and Polysaccharides (from permanent slides). 3. Demonstration of dialysis (glucose and starch). Study of plasmolysis and deplasmolysis using red onion peel/Rhoeo. 4. Study of effect of temperature, pH and heavy metals on the action of Urease, Catalase. 5. Separation and identification of amino acids by paper chromatography. 6. Isolation of DNA from cauliflower by spooling method. 7. Preparation of temporary slides to study different stages of mitosis and meiosis (Allium roots and buds) and meiosis in grasshopper testis. Unit II Developmental Biology (Plants) 1. Pollen germination by Hanging drop culture. 2. Study of structure of anther, types of tapetum, microsporogenesis, types of ovules and embryo sac development (monosporic) (through photographs/permanent slides). 3. Study of mature embryo sac through electron micrographs showing egg apparatus. 4. Endosperm types, stages of embryo development — through photographs/ permanent slides. Unit III Developmental Biology (Animals) 1. Study of developmental stages in frogs — whole mount and sections (permanent slides), cleavage stages, blastula, gastrula, neurula, tail bud tadpole. 2. Study of whole mounts and sections of chick embryo at different stages, primitive streak (24, 28, 33, 48, 72, and 96 hours). 234 II. Genetics, Biotechnology and Immunology Marks : 50 Unit I Genetics 1. Study of gene interaction/deviations from the Mendelian ratios using seed Samples in ratio of 9:7., 9:4:3, 13:3, 9:6:1, 15:1 and 12:3:1. 2. To study of the karyotype of diploid and polyploidy of the same genus through photographs; and aneuploids (Down’s, Turner’s and Klinefelter’s Syndrome). 3. Preparation of karyo of type and idiogram from the given photograph of somatic metaphase chromosomes (Allium and Human). 4. Study of the organization of DNA in the eukaryotic chromosome (through illustration). 5. Study of salivary gland and lampbrush chromosomes, laggards, bridges, multivalents and translocation ring. 6. Study of banding patterns (Q,C,G) through photographs. 7. To study the sex chromosomes of Melandrium/Coccinia (Permanent slide/Photographs). 8. Temporary preparation of Barr bodies. 9. Study of inherited characters in human: colour blindness and PTC test. Unit II Biotechnology 1. Construction of phylogenetic tree from DNA sequences from data provided. 2. Study of genetic engineering techniques with help of photographs (PCR, Southern blot, GISH, FISH, DNA Fingerprinting). 3. Survey of Useful Bioinformatics sites on internet, gene and protein databases, genome and organism specific database, multiple sequence alignment. Unit III Immunology 1. Isolation, staining and counting of mononuclear cells from peripheral blood. 2. Demonstration of primary (Bone marrow & Thymus and secondary immune organs (spleen, lymph nodes) in rat. 3. Determination of ABO blood groups and Rh-factor. 235 AGROCHEMICALS AND PEST MANAGEMENT ACP 301 APPLIED ENTOMOLOGY (72 Lectures) Total Marks : 100 Unit I Fundamental of Entomology (a) Elementary knowledge of collection, preservation and culture techniques of insects. (b) Classification: Basic principle of classification of insects. Characters and examples of Coleoptera, Lepidoptera, Hemiptera and Diptera. (c) Type study: Cockroach. Unit II Insect Pests (A) Bionomics and management of the following pests (a) Rice - Leptocorisa acuta (b) Wheat - Sesamia inferens (c) Pulses - Helicoverpa armigera (d) Sugarcane - Tryporyza armigera (e) Cotton - Earias vitella, Pectinophora gossypiella (f) Vegetable - Raphidopalpa foveicollis, Leucinodes orbonalis (g) Fruit - Papilio demoleus (h) Stored Grain Pests - Sitophilus oryzae, Callosobruchus chinensis, Corcyra cephalonica and Trogoderma granarium. (B) Bionomics and control of locusts and termites. Unit II Useful Insects and Practices of Pest Control (a) Agricultural Pest: mechanical, cultural, chemical, biological, sterileinsect technique, genetic and quarantine. (b) Medically important Pests : Economic important and management of Fleas, bed bugs, mosquitoes, houseflies, and lice. (c) Outlines of sericulture, apiculture and lac culture. 236 Suggested Readings 1. Atwal, A.S. and Dhaliwal, G.S. (1999) Agricultural Pests of South Asia and their management. 2. Metcalf, C.L. and Flint, W.P. (1962) Destructive and useful insects, McGraw-Hill Book Company. 3. Ross, Herbert H. (1956) A Text book of Entomology, John Wiley and Sons. 4. Hill, Dannis S. (1993) Agricultural insects pests of the tropics and their control; Cambridge University Press. 5. Ross David (2004) Insects of stored products, Manson Publication. 6. David and Ananthakrishan (2004) General and Applied Entomology, McGraw-Hill Publication. 237 ACP 302 INSECTICIDES, PESTICIDE FORMULATION, ANALYSIS, QUALITY CONTROL (72 Lectures) Maximum Marks : 100 Unit I Carbamate insecticides Preparations and pesticidal properties of following carbamate insecticides: Carbaryl, methomyl. Mode of action of carbamate insecticides. Unit II Organophosphorus pesticides Nomenclature and structural diversities of organophosphorus compounds; Preparation and pesticidal properties of the following organophosphorus pesticides: Parathion, methyl parathion, melathion, Mode of action of organophosphorus insecticides. Unit III Organochlorine Insecticides Preparation, properties and uses of DDT and its analogs: Methoxy chlor and DDD Bridged diphenyl acardies: Kelthane, Chlorobenzilate Hexachlorcyclohexanes (stereochemistry). The chlorinated cylodienes and their stereochemistry: Chloridane, heptachlor, aldrin, dialdrin endosulfan. Mode of action of organochlorine insecticides. Unit IV Botanical Insecticides (No structure elucidation or synthesis is required for the following compounds): Nicotine and its analogs Pyrethrum Properties of Natural pyrethroids Synthetic analogs of pyrethroids: Allethrin, fenvalerate, decamethrin, Mode of action of pyrethroids. 238 Unit V Pesticide Formulations Different types of formulations and their physio-chemical characteristics and important BSI specification. Wettable powders Solutions Emulsifiable concentrates, Aerosols. Dusts. Granules. Unit VI Analytical Techniques involved in Pesticide Analysis Principle underlying the following analytical techniques: Titrimetric methods, Chromatography methods: TLC, Gas chromatography, Liquid chromatography and Colorimetric methods. Unit VII Analysis of formulations and pesticide residues Principle and methods underlying the analysis of the following pesticides: DDT, BHC, Baygon, Melathion, 2,4-D, paraquat. Unit VIII Quality Control Objectives and importance. Responsibilities, establishment of quality control Laboratory. Rules and regulations governing quality. Analysis of active ingredients. CIPAC, EPA, WHO, FAO & BIS guidelines and specifications and their comparison vis-avis quality of materials, adulteration and common adulterants. Suggested Readings 1. Perry, A.S., Yamamoto, I., I. Shaaya and R. Perry, Insecticides in Agriculture and Environment, Narora Publishing House. 2. S.K. Khaitan, Pesticide Formulation, UNIDO, VIENNA. 3. B.S. Parmar and S.S. Tomar. Pesticide formulation, CBS Publishers and Distributors, New Delhi. 4. R.J. Kuhr, H.W. Derough, Carbamate Insecticides, Chemistry, Biochemistry and Toxicology, CRC Press. 5. R. Wade, M. Dekker, Pesticide Formulation. 6. R.L. Metcalf Organic Insecticides, their Chemistry and mode of action. 7. O’Brien, R.D., Insecticide, Action and Metabolism, Academic Press, New York and London. 239 ACP 303 AGROCHEMICALS AND PEST MANAGEMENT LAB-II Total Marks: 100 PART- I 1. Collection of preservation of insects. 2. Identification and life history of economically important pests listed in the syllabus of theory. 3. Laboratory rearing of one Phytophagous, and one stored grain insect of economic importance. 4. Prepare key for the identification of insect up to orders (Coleoptera, Lepidoptera, Hemitera and Diptera) given insects. 5. Formulations of insecticides. 6. Bioassay of mosquito larvae, adult housefly or stored grain pest using any one insecticide, and calculate LD 50/ LC 50. 7. Acquaintance with insecticide dusting and spraying equipment and its working. 8. Trip to agricultural field and granary for the on spot study of damages caused by insect pests. PART-II 1. To calculate acidity/alkalinity in given sample of pesticide formulations as per BIS specifications. 2. To prepare a sample of 5% granules and analyze the quality control of formulation parameters. 3. To find the percentage purity of DDT in a given sample (hydrolysable and non-hydrolysable chlorines). 4. Prepare emulsifiable concentrate ofmelathion and its analysis as per specifications (cold test and emulsion stability test). 5. Preparation of WDP (Wettable Dust Powder) concentrates of DDT and its analysis by ISI specifications (physiochemical characteristics). 6. To estimate the active ingradient in the formulations and technical products of following pesticides: Melathion, Carbaryl,2,4-D and 2,4,5 T. 7. Sampling, clean up and analytical techniques in residue analysis. 8. Preparation of simple organophosphates, phosphonates and thiophosphates. 240 MATHOPHYSICS MP 301 MATHEMATICS - 2 (4 Lectures plus one tutorial per week) Total Marks : 150 Internal Assessment : 38 marks Examination : 112 marks Duration : 3 Hours Unit I Infinite Series (24 L) 28 Convergent sequences, Statement and illustration of Cauchy convergence criterion for sequences. Cauchy’s theorem on limits, monotone sequences and their convergence. Definition and a necessary condition for convergence of an infinite series. Cauchy convergence criterion for series, positive term series, geometric series, comparison test, limit comparison test, convergence of p-series, Root test, Ratio test, alternating series, Leibnitz’s test. Definition and examples of absolute and conditional convergence. Unit II : Differential equations (38 L) 44 First order exact differential equations, Integrating factors, rules to fine an integrating factor. First order higher degree equations solvable for x, y, p = dy/dx. Methods for solving higher-order differential equations. Solving a differential equation by reducing its order. Linear homogenous equations with constant coefficients. Linear non-homogenous equations. The method of variation of parameters. The Cauchy-Euler equation. Simultaneous differential equations. Applications of differential equations : the vibrations of a mass on a spring, mixture problem, free damped motion, forced motion, resonance phenomena, electric circuit problem, mechanics of simultaneous differential equations. Order and degree of partial differential equations, concept of linear and non-linear partial differential equations, formation of first order partial differential equations. Linear partial differential equations of first order, Lagrange’s method, Charpit’s method, classification of second order partial 241 differential equations into elliptic, parabolic and hyperbolic through illustrations only. Unit IV (Algebra) (34 L) 40 Definition and examples of real or complex vector spaces. Subspaces and their properties. Linear independence and dependence, basis, invariance of basis, size, dimension of a vector space. Real or complex Matrices as Linear transformations, eigen values & eigen vectors, Cayley Hamilton theorem. Methods of finding inverse of a non singular matrix. Groups : Definition and examples of groups, examples of abelian and non-abelian groups : the group Zn of integers under addition modulo n and the group U (n) of units under multiplication modulo n. Cyclic groups, examples of groups from number systems, complex roots of unity, circle group, the general linear group GLn (n,R), groups of symmetries of (i) an isosceles triangle, (ii) an equilateral triangle, (iii) a rectangle, and (iv) a square, groups of transformations in a plane, the permutation group sym(n), group of quaternions, crystallographic groups. Subgroups, cyclic subgroups, examples of subgroups including the centre of a group Cosets, index of a subgroup, Lagrange’s theorem, order of an element, Statement and Interpretation of Euler and Fermat’s theorem, order of HK where H and K are subgroups. Normal subgroups : The definition, examples, and characterizations. Rings : Definition and examples of rings, examples of commutative and non-commutative rings : rings from number systems, Zn, the ring of integers modulo n, ring of real quaternions, rings of matrices, polynomial rings, and rings of continuous functions. Subrings and ideals, integral domains and fields, Examples of fields : Zp, Q, R and C. Field of rational functions. 242 Suggested Readings 1. Paul Duchateau, David W. Zechmenn, Partial Differential Equations, Tata McGraw Hill, 2005. 2. J. Durbin, Modern Algebra and introduction, Wiley Student Edition, 2005. 3. E. Fischer, Intermediate Real Analysis, Springer Verlag, 1983. 4. Joseph A Gallian : Contemporary Abstract Algebra, fourth edition, Narosa, 1999. 5. B. Kolman, D.R. Hill, Introductory Linear Algebra with Applications, Pearson Education, 2003. 6. Seymour Lipsdchutz, Linear Algebra, Schaum Series, Tata McGraw Hill, 1989. 7. S. L. Ross, Differential Equations, John Wiley and Sons, Third Edition, 1984. 8. I. Sneddon, Elements of Partial Differential Equations, McGraw Hill International Editions, 1967. 243 MP 302 OPTICS, ELECTRONICS AND MODERN PHYSICS (70 Lectures) Total Marks: 100 Optics (20 L) Fresnel diffraction. Half period zones and zone plate. Diffraction due to a straight edge and single slit. Fraunhofer diffraction. Intensity due to single slit. Plane transmission grating and its resolving power. Laser: Working principle, thermal equilibrium of radiation, principle of detailed balance, Population inversion, construction and working of He- Ne laser. Optical Fiber: total internal reflection, critical angle, numerical aperture, acceptance angle, types of optical fibers (definition only). Electronics and Communication (20 L) UJT characteristics and relaxation oscillator. Construction and working of FET, comparison between CE, CB and CC configurations of BJT. Static and dynamic load line, biasing of transistor circuit (fixed and self). Class A, B and C amplifiers (definition). Communication: Propagation of radio waves, troposphere and ionosphere propagation. Need for modulation, basis concepts of amplitude, frequency and phase modulation and demodulation. Gestationary satellites, antenna look angles, orbital classifications, spacing and frequency allocation, radiation patterns. Satellite system link model-uplink, transponder, downlink, transmit power. Bit energy, effective isotropic radiated power. Idea of GPS services. Quantum Mechanics (15 L) Schrodinger equation. Operators, average value. Time independent Schrodinger equation, requirements of a wave function, probabilistic interpretation. Solution of Schrodinger equation in one dimension, particle in box, step potential: barrier penetration and tunneling. Nuclear Energy (9 L) Binding energy, nuclear fission and fusion. Fission reactor. Fusion energy in Sun. Controlled thermonuclear fusion. Lawson criteria, elementary ideas 244 on magnetic confinement (Tokmak) and intertially confined laser driven fusion. Physics of Materials (6 L) Amorphous, crystalline and polycrystalline solids, Band theory of solids, energy band diagram in conductors, insulators and semiconductors, n and p type semiconductors, Hall effect, Quantum Hall effect. Superconductivity, Meissner effect, critical field Type I and II superconductors, London equation, penetration depth. Suggested Readings F.A. Jenkins and H.E. White.: Fundamentals of Optics (McGraw Hill). J. Millmnn and C.C. Halkias: Integrated Electronics (Tata McGraw Hill). D. Roddy and J. Coolen: Electronic Communication (Prentice Hall). S.T. Thornton and A. Rex : Modern Physics for Scientist and Engineers 3rd Edition (Brooks-Cole). 245 MP 303 PHYSICS LAB - II Total Marks : 50 1. Determination and magnifying and resolving power of a telescope. 2. Determination of ? of light by Newton’s rings. 3. Determine the Cauchy’s constant and dispersive power of Prism. 4. Determination of ? of sodium light by difiraction grating. 5. Determination of ? of sodium light by Fresnel’s biprism. 6. Determination of diameter of a wire by diffraction. 7. Design of CE amplifier of desired gain. 8. Study of Phase shift oscillator. 9. Study of UJT characteristics and relaxation oscillator. 10. Amplitude modulation using CE amplifier. 11. Study of PLL IC (capture andlock range). 12. Study of 4-bit sift register. Note: At least eight experiments should be performed by each student. 246 SERICULTURE SC 301 SERICULTURE CROP IMPROVEMENT AND MANAGEMENT (75 Lectures) Total Marks: 100 Section - A — Sericulture Crop Improvement 1. Sericulture Crop (2 L) Introduction and its classification, Mulberry and Silkworm cocoon crop — significance of its improvement and management in sericulture development. 2. Mulberry Crop Improvement (18 L) Cytogenetics and genetic variability of mulberry, Mulberry germplasm maintenance and its significance, Mulberry breeding — Objectives and different methods — Plant Introduction and acclimatization, selection — Mass, pure line, clonal selection, Polyploidy, Mutation breeding, Breeding for disease and drought resistance. Tissue Culture — Introduction, Organization of plant tissue culture laboratory, Micro propagation, Different cultures — meristem, callus, anther, pollen, endosperm. Cryopreservation, Evaluation of mulberry genotypes and release of different varieties. 3. Silkworm Cocoon Crop Improvement (17 L) Silkworm as a ideal laboratory tool for genetical studies, Cytogenetics of silkworm, Genetics of cocoon colour, inheritance of voultinism and moultinism, mosaicism in silkworm and their selection, Silkworm Breeding — aims and objectives, silkworm breeding in India, Silkworm races — their origin and distribution, parameters relevant to silk production, Types of crosses, auto sexing breeds, heterosis and its exploitation in silkworms, Silkworm germplasm and its management. 247 Section - B — Sericulture Crop Management 1. Mulberry disease and pest management (16 L) Concept of plant diseases, classification, survey of mulberry diseases, importance of mulberry protection, Influence of abiotic and biotic factors on incidence of mulberry diseases. Fungal, viral, mycoplasmal and root knot nematode disease of mulberry - occurrence, causative agents, symptoms, epidemiology, prevention and control methods and mineral deficiency diseases of mulberry. Fungicides - their formulations and preparation. Mulberry Pests: Major, minor and resurging pests of mulberry- Occurrence, classification and their characteristic features, damage, life cycle, symptoms, prevention and control methods. 2. Silkworm Disease and pest management (15 L) Introduction and classification of silkworm diseases, Silkworm diseases — Microsporadian, Viral, Bacterial and Fungal — Causative agents, its classification and characteristic features, damage, source and mode of infection, symptoms, disinfection process, prevention and control methods. Silkworm Pests: Major, minor and resurging pests of silkworms — Classification, life cycle, damage, alternate hosts, prevention and control methods. 3. Seri-biotechnology (4 L) New R&D area in sericulture, Use of biotechnological methods in sericulture crop improvement and management, prospects of biotechnology in sericulture development. 4. Integrated Pest and Disease Management (3 L) Integrated pest and disease management and its effect on sericulture success, Sericultural practices in China and Japan for effective pest and disease management and their relevance in Indian conditions. 248 Suggested Readings 1. Aruga, H.: Principles of Sericulture, Oxford & IBH Publishing Co. Pvt. Ltd., 1994. 2. Devaiah, M.C. Narayanswamy, K.C. and Maribashetty, V.G.: Advances in Mulberry Sericulture, 1st Edition, C.V.G. Publications, Bangalore, 1999. 3. Devaiah, M.C., Narayanswamy, K.C. and Govindan, R.: Principles of Silkworm Pathology, 1st Edition, Seri Scientific Publishers, Bangalore, 1998. 4. ESCAP, United Nations, Rome: ESCAP Manual on Principles and Techniques of Silkworm Breeding, United Nations, New York, 1993. 5. ESCAP, United Nations, Rome: ESCAP Manual on Diseases and Pests of Mulberry and Silkworm, Thailand. 6. FAO United Nations, Rome: FAO Manuals on Sericulture (Volume-I - Mulberry Cultivation, Volume - II - Silkworm Rearing), FAO, United Nations, Rome. 7. Sarkar, Dilip De: Silkworm Biology, Breeding and Genetics, 1st Edition, Vikas Publishing House Pvt. Ltd, 1998. 8. Tazima, Y.: Silkworm — An Important Laboratory Tool, Kodansha Ltd., Tokyo, Japan. 9. Tazima, Y.: The Genetics of Silkworm, Logos Press & Academic Press, Tokyo, Japan. 10. Sathe, T.V. and Thite, S.H.: Sericulture and Pest Management, 1st Edition, Daya Publishing House, New Delhi, 2001. 11. Ullal and Narasimanha: Handbook of Practical Sericulture, 4th Edition, CSB Publications, 1994. 249 SC 302 SILKWORM SEED TECHNOLOGY AND SILK TECHNOLOGY (75 Lectures) Total Marks: 100 Section - A – Silkworm Seed Technology 1. Silkworm Seed Technology (1 L) Introduction, Significance of silkworm eggs for sericulture industry. 2. Silkworm Seed Organization (8 L) Introduction, Significance, Different types of silkworm seed organization systems — 4 Tier and 3 Tier system, Constituents of silkworm seed organization system — Basic Seed farm, Seed Multiplication farm, Seed Areas— Identification, concept of selected seed areas/villages, Seed cocoon markets and its importance, Seed Legislation Act — rules and regulation. 3. Disinfection in seed production units (3 L) Disinfection and its importance, different types of disinfectants, calculation of surface area for disinfection process, implementation of disinfection process. 4. Seed Production Centers (12 L) Grainages — Introduction, function production planning, grainage equipments and their uses, Grainage activities — Procurement and transportation of seed cocoons, Processing and preservation of seed cocoons, Role of environment in cocoon preservation, Cocoon sorting, Sex separation. Synchronization of moth emergence. Coupling and decoupling of moths, Oviposition, Method of egg preparation — sheet and loose eggs, Mother moth examination, Surface sterilization, Environmental conditions for grainage activities, grainage management and its economics. 5. Handling of Silkworm Egg (14 L) Bivoltine and multivoltine silkworm eggs and their characteristic features, diapausing character of bivoltine eggs and its biology. Acid 250 treatment — its importance and selection of appropriate method. Types of acid treatment — Hot acid and cold acid treatment — advantages and disadvantages, cold storage and preservation of silkworm eggs, postponement of hatching of silkworm egg. Hibernation schedules — introduction, types and uses. Section - B - Silk Technology 1. Textile Fibers (5 L) Classification and broad characteristics of different fibers. Properties of silk — physical and chemical, different factors affecting the quality of raw silk. 2. Cocoon Quality (3 L) Cocoon as a raw material — its significance, physical and chemical characteristics, procurement, sorting and transportation. 3. Pre Reeling Operations (5 L) Cocoon stifling, Cocoon boiling/cooking; Cocoon brushing - Different types and their merits and demerits. 4. Reeling Operations (10 L) Introduction, different reeling terms, Reeling process — Different reeling machines and their working, reel permeation, rereeling, lacing, skeining, raw silk packing, raw silk testing and grading, silk reeling water management. Silk reeling management — process control and its effect on quality, Bivoltine silk reeling technology for quality, silk, byproducts of silk reeling process, Silk reeling waste and its utilization, Spun silk industries. 5. Post Reeling Operations (10 L) Objectives of various operations: Silk Throwing, Wet processing — degumming, bleaching, dyeing, Silk Weaving — Warp and weft preparation, An overview of weaving process. Weaving appliances — Handlooms, power looms and recent advanced looms; Silk Printing — Printing styles — Direct, discharge and resist type, printing tools and devices and quality control in printing and post printing operations, Finishing of silk— Mechanical and Chemical. 251 6. Fabric Quality (4 L) Perspective of fabric quality, fabric defects — warp and weft way defects, importance of crimp, steps required for production of quality fabrics. Suggested Readings 1. Narasimhanaha, M. N.: Manual on Silkworm Egg Production, Central Silk Board, Bangalore, 1998. 2. Biram Saheb, N. M. Sengupta, K., Reddy, G. Vernanada: A Treatise on the Acid treatment of Silkworm Eggs, CSR&TI, Central Silk Board, Mysore. 3. FAO United Nations, Rome: FAO Manuals on Sericulture (Volume III — Silk Reeling) FAO, United Nations, Rome. 4. CSTRI, CSB, Bangalore, Manual on Bivoltine Silk Reeling Technology, 2002. 5. Mahadevappa, D.: Mulberry Raw Silk Reeling Technology, Oxford & IBH Publishing Co. Pvt. Ltd., 2000. 6. Rui, Huang Guo: Silk Reeling, Oxford & IBH Publishing Co. Pvt. Ltd., 1998. 7. Gulranjani, P.: Chemical Processing of Silk, Department of Textile Technology, IIT, New Delhi, 1993. 8. Gulranjani, P.: Silk Bleaching, Dyeing and Printing, Department of Textile Technology, IIT, New Delhi. 252 SC 303 : SERICULTURE LAB - II (Based on Paper SC 301 & SC 302) Total Marks: 100 1. Study of stains, fixatives, pre treatment solutions and cytological techniques. 2. Commercial characteristics of some evolved varieties of mulberry, study of disease resistant and draught tolerant genotypes of mulberry. 3. Study of Meiosis in mulberry buds. 4. Pathology — Identification, isolation and symptoms of fungal, bacterial, viral, nematode and other minor diseases of mulberry; Isolation and identification of fungal spores, nematode egg masses, larvae and adults. Collection and preservation of diseased plant samples. Fungicide formulations and their application. 5. Pests — Identification and collection of major pests and their developmental stages, Study of all minor pests, biological agents used to control pests; Pesticide preparation and their application. 6. Morphological variations of egg, larval, cocoon, pupal and moth characters of different races of silkworm. 7. Analysis of quantitative traits : % heterosis, chi-square and t-test. Study of sex linked traits, differentiation of silkworm breeds, Evaluation of pure races and hybrids. 8. Heterosis: Single, three way and double cross calculations; inbreeding and inbreeding depression calculations. 9. Pathology: Causative agents, classification, occurrence, mode of transmission, symptoms, prevention and control of silkworm diseases — Pebrine, Grasserie, Flacherie, Muscardine and Aspergillosis. 10. Pests : Classification, damage, developmental stages, prevention and integrated control of major and minor pest of silkworm — Uzifly and Dermestid Beetle, Uzifly infestation and its assessment, collection and preservation of insect pests. 253 11. Use of biotechnological tools for disease detection — Bioassays, Dipstick immunoassays, Agarose gel Double Diffusion tests for BmIFV and BmDNV. 12. Visit to Microbiological and Biotechnological laboratory. 13. Model grainage plan, Grainage equipments and their uses. 14. Seed Cocoon processing and handling — Deflossing, Cocoon sorting, Cocoon preservation, Pupal midgut examination. 15. Moth emergence, Selection of moths, Pairing, de pairing and preservation of male moths, Oviposition, preparation of eggs — sheet and loose eggs, Surface sterilization of eggs. 16. Mother Moth Examination — Individual, Mass moth examination. 17. Acid Treatment of Bivoltine eggs — Hot and Cold acid treatment. 18. Visit to Grainage and Cold Storage facility. 19. Identification of different textile fibres e.g. silk, cotton, wool and other synthetic fibres by physical methods — microscopic and flame test, Chemical and other confirmation tests. 20. Categorization of different type of cocoons — good and defective cocoons, calculation of their percentage in a lot. 21. Determination of commercial characters of a cocoon — Average cocoon weight, shell weight, shell ratio or shell percentage, Average filament length, denier. 22. Reeling water analysis — pH, Conductivity, chloride content, total hardness, m-alkalinity. 23. Reeling on Epprouvate — Single cocoon reeling, determination of average filament length and average denier size. 24. A visit to state/CSB silkworm seed production centers for study of silkworm seed production facilities. 25. A visit to CSTRI, Bangalore for Study of pre-reeling, reeling and post reeling operations. 26. Summer School training Programme (to be organized by Central Silk Board) during the beginning of the session (Part-III) covering all aspects of sericulture. 254 ELECTIVE SUBJECTS One elective subject may be chosen out of the following: Sr.No. Subject 1. Green Chemistry 2. Polymer Science 3. Biotechnology 4. Forensic Science 5. Earth System Science 6. Intellectual Property Rights 7. Computational and Discrete Mathematics* 8. Mathematical Methods in Life Sciences * Only for students of B.Sc. Physical Sciences/ Applied Physical Sciences. 255 EL 310 (i) GREEN CHEMISTRY (Total Lectures: 50) Total Marks : 50 With the environmental concern and shrinking resources acquiring enormous proportions, it has become imperative to devise safer alternative materials and technology that would ensure the human sustenance. This course intends to take the students through the newer, environment friendly products and procedures and incite them to take a more holistic view of different chemical processes. Unit I Introduction to Green Chemistry What is Green Chemistry? Need for Green Chemistry. Goals of Green Chemistry. Limitations/Obstacles in the pursuit of the goals of Green Chemistry. Unit II Principles of Green Chemistry and Designing a Chemical Synthesis Twelve principles of Green Chemistry with their explanations and examples; Designing a Green Synthesis using these principles; Prevention of Waste/Byproducts; maximum incorporation of the materials used in the process into the final products (Atom Economy); prevention/minimization of hazardous/toxic products; designing safer chemicals — different basic approaches to do so; selection of appropriate auxiliary substances (solvents, separation agents), green solvents, solventless processes, immobilized solvents and ionic liquids; energy requirements for reactions — use of microwaves, ultrasonic energy; selection of starting materials - use of renewable rather than depleting starting materials; avoidance of unnecessary derivatization — carefull use of blocking/protecting groups; use of catalytic reagents (wherever possible) in preference to stoichiometric reagents; designing of biodegradable products; prevention of chemical accidents; strengthening/development of analytical techniques to prevent and minimize the generation of hazardous substances in chemical processes. 256 Unit III Examples of Green Syntheses /Reactions 1 Green Syntheses of the following compounds : adipic acid, catechol, BHT, methyl methacrylate, urethane, aromatic amines (4-aminodiphenylamine), benzyl bromide, acetaldehyde, disodium iminodiacetate (alternative to Strecker synthesis), citral, ibuprofern, paracetamol, furfural. 2 Microwave assisted reactions in water : Hofmann Elimination, Hydrolysis (of benzyl chloride, benzamide, n-phenyl benzamide, rnethylbenizoate to benzole acid)), Oxidation ( (of toluene, alcohols). Microwave assisted reactions in organic solvents : Esterification, Fries rearrangement. Orthoester Claisen Rearrangement. Diels Alder Reaction. Decarboxylation. Microwave assisted solid state reactions : Deacetylation, Deprotection. Saponification of esters, Alkylation of reactive methylene compounds reductions, synthesis of nitriles from aldehydes; anhydrides from dicarboxylic acid; pyrimidine and pyridine derivatives; 1, 2-dihydrotriazine derivatives; benzimidazoles. 3. Ultrasound assisted reactions : Esterification, saponification, substitution reactions, Alkylations, oxidation, reduction, coupling reaction, Cannizaro reaction, Strecker synthesis, Reformatsky reaction. 4. Selective methylation of active methylene group using dimethylcarbonate : Solid-state polymerization of amorphous polymers using diphenylcarbornate; Use of “Clayan”, a nonmetallic oxidative reagent for various reactions; Free Radical Bromination; Role of Telliurium in Organic Syntheses. Biocatalysis in Organic Syntheses. Unit IV Future Trends in Green Chemistry Oxidation reagents and catalysts; Biomimetic, multifunctional reagents; Combinatorial green chemistry; Proliferation of solventless reactions; oncovalent derivatization. Green chemistry in sustainable development. 257 Suggested Readings 1. Ahiuwalia V.K.. & Kidwai M.R. New Trends in Green Chemistry, Anamalaya Publishers, 2005. 2. Anastes, P.T. and Warmer, J.K., Oxford Green Chemistry, Theory and Practical University Press, UX., 1998. 3. Matlack A.S., Introduction to Green Chemistry, Marcel Deckkar, N.Y. 2001. 4. Cann M.C. and Connely M.E., Real-word cases in Green Chemistry, American Chemical Society, Washington DC, 2000. 5. Ryan M.A. and Tinnesand. M., Introduction to Green Chemistry, American Chemical Society, Washington DC., 2002. 258 EL 310 (ii) POLYMER SCIENCE (50 Lectures) Total Marks: 50 The primary objective of Polymer Science course is to prepare skillful Polymer Scientists to meet the growing requirements in Polymer based industry. Government and other R &D organization and teaching institutions. Unit I Introduction and histoiy of polymeric materials. Different Schemes of Classification of Polymers. Polymer nomenclature. Molecular forces and chemical Bonding in polymers. The texture of Polymers. Unit II Functionality and its importance, Criteria for synthetic polymer formation, Classification of polymerization processes, Relationships between functionality, extent of reaction and degree of polymerization. By-functional systems, Poly-functional systems. Unit III Kinetics of Polymerizaiion : Mechanism and kinetics of step growth, radical chain growth, ionic chain (both cationic and anionic); and coordination Polymarizations, Mechanism and kinetics of copolymerization, polymerization techniques. Unit IV Crystallization and Crystallinity. Determination of Crystalline melting point and degree of Crystallinity. Morphology of crystalline polymers, Factors affecting crystalline melting point. Unit V Nature and structure of polymers-Structure Property relationships. Determination of molecular weight of polymers, (Mn, Mw, etc), by end group analysis, viscometry, light scattering and osmotic reassure methods. Molecular weight distribution and its significance. Polly-disparity index. Unit VI Glass transition temperature (Tg) and determination of Tg, Free volume theory, WLF equation, Factors affecting glass transition temperature (Tg). Unit VII Polymer Solution — Criteria for polymer solubility, Solubility parameter, Thermodynamics of polymer solutions, entropy, 259 enthalpy, and free energy change of mixing of polymers solutions, Flory-Huggins theory, Lower and Upper critical solution temperatures. Unit VIII Properties of Polymer (Physical, Thermal, Flow & Mechanical Properties). Unit IX Brief introduction to preparation, structure, properties and application of the following polymers. Polyolefins, Polystyrene and styrene copolymers, Poly (vinyl chloride) and related polymers, Poly (vinyl acetate) and related polymers, Acrylic polymers, Fluoro Polymers, Polyamides and related polymers. Phenol formaldehyde Resins (Bakelite, Novalac), Polyurethanes, Silicone Polymers, Polydienes, Polycarbonates, Conducting Polymers, {Polyacetylene, Polyaniline, Poly (p-phenylene sulphide Polypyrole, Polythiophene)}. Suggested Readings 1. Seymour Polymer Chemistry, Marcel Dekker, Inc. 2. G. Odian, Principles of Polymerization , John Wiley. 3. F.W. Billmeryer, Text Book of Polymer Science. John Wiley. 4. P.Ghosh, Polymer Science & Technology, Tata McGraw-Hill 5. R.W. Lenz, Organic Chemistry of synthetic High Polymers. 260 EL 310 (iii) BIOTECHNOLOGY (50 Lectures) Total Marks: 50 The purpose of this course is to provide to the students of Science, a basic understanding of the principles, tools and techniques, and applications of the fast expanding field of Biotechnology. This would help the students to develop interactions/linkages with the industry and venture into Science entrepreneurship. Unit I Biotechnology Scope and Applications. Overview of Tools and Techniques. Unit II Industrial Microbiology Microbial resources for food, food additives, flavours, feed, single cell proteins, solvents, enzymes, organic acids, vitamins, pharmaceuticals, agrochemicals, bio-fertilizers. Waste decomposition and conversions, bio-fuels. Bioremediatiton. Recombinant proteins Unit III Strain improvement Screening, selection, mutation, recombination, protoplast fusion, DNA technology. Unit IV Fermentation Different types of fermentation - submerged and solid state; batch, fed batch and continuous; product-based - enzymes, alcohol, methane, acid, mixed acid and solvent. Types of fermenters - stirred tank, air lift, fixed bed and fluidized. Down stream processing - filtration, centrifugation, extraction, chromatography, spray drying and lyophilization. Unit V Plant Biotechnology Plant tissue culture and somatic cell genetics and their applications in agriculture, plant transformation - vectors and methods, genetic engineering and transgenic plants with useful agronomic traits and products. 261 Unit VI Animal Biotechnology Cell culture and production of bio-products, gene manipulation and transgenic technology, gene therapy, vaccines, hybridoma technology and immunodiagnostics. Unit VII Bio safety Physical and Biological Containment, environmental coconcerns. Suggested Readings 1. P.K Gupta, Biotechnology and Genomics, Rastogi Publishers, (2003). 2. B.D. Singh, Biotechnology, Kalyani Publishers, 1998 (Reprint 2001). 3. T.A. Brown, Gene cloning and DNA analysis: An Introduction, Blackwell Science, 2001. 4. M.K. Razdan, Introduction to plant tissue culture, Oxford & IBH, New Delhi, 2003. 5. Bernard R. Click & Jack J. Pasternak, Molecular Biotechnology, ASM Press, Washington, D.C., 1998. 262 EL 310 (iv) FORENSIC SCIENCE (50 Lectures) Total Marks: 50 Forensic Science pertains to analysis and examination of Physical evidence recovered from a crime scene to aid legal proceedings. Examinations of fingerprint, toxic substances detection of blood and other biological fluids, as well as examination of skeletal material, hair fiber etc is performed to provide scientific opinion for legal. Unit I Definition, History, Development and Scope of Forensic Science. Divisions of Forensic Science and Laboratory Set up. Unit II Basic Principles, theory and application of spectroscopy (U. V., I. R., Atomic Absorption Emission and Mass) and its forensic applications. Unit III Electrophoresis (Immuno and Iso-electrofocusing) theory, principle and techniques. X-ray (Hard and Soft) techniques and their forensic applications. Unit IV Forensic Chemistry: Introduction, Conventional methods of chemical analysis, presumptive tests (colour & spot); Drugs of Abuse: Introduction and classification; Forensic Toxicology: Introduction and Geneial methods of chemical analysis for alcohol. Classification of poisons. Unit V Questioned documents: Definition, handwriting characteristic, natural variation, comparison and forgery; Forensic photography — techniques and important of photography. Unit VI Fingerprint Identification: History and development, biological basis of fingerprints, pattern types, scene of crime prints, methods of processing latent/fingerprints, ridge characteristics, comparison of fingerprints for establishing complete identity. Unit VII Tool marks: their identification and importance in forensic science; Trace evidence: Definition, identification and their importance in forensic science. Unit VIII Identification and detection of biological fluids (Blood, Semen, Saliva and Urine) and their Medico-logical importance. 263 Unit IX Personal Identification through Somatometry and Somatoscopy; Study of hair and fibers. Unit X Examination of skeletal remains-identification of bones, differentiation between human and non human, determination of age, sex and height from skeletal remains. Unit XI Modern Developments and their concepts (Nacre analysis, Brain fingerprinting, DNA Profiling, voice identification, Cyber crime, Forensic Odontology and Bitemarks). Note : Practical demonstration are compulsory as without the demonstration the students would not be able to understand the value of the specific topics of Forensic Science. Practical demonstration of procedure of taking fingerprints; identification of pattern types, developing latent fingerprints (Powder Method), spot test for blood identification,Somatoscopic observations, Age and sex determination from skull, estimation of height from long bones, hair morphology, tests for fiber identification. Suggested Readings 1. Saferstein, R. Criminalistics. Prentice Hall, N.J., (1998). 2. Sharma, B.R. Forensic Science in Criminal Investigation and Trials, Central Law Agency, Allahabad, (2003). 3. Eckert, W. G. Introduction of Forensic Science, CRE Press. Bock Raton, (1997). 4. Singh, I.P. and Bhasin M.K. A Laboratory Manual of Biological Anthropology. K.R. Enterprises, N. Delhi, (2005). 5. Nath, S. An Introduction to Forensic Anthropology. Gian Publishing House, N.Delhi, (1989). 6. Nath, S. Personal Identification through Fingerprints. Shree Publisher & Distributors, New Delhi, (2006). 264 FL. 310 (v) : EARTH SYSTEM SCIENCE (50 Lectures) Total Marks : 50 The course on Earth Systems Science offers integrated understanding to the various major earth systems including the solid earth, the hydrosphere and the atmosphere. The interactive processes that couple these major systems are also emphasized. Unit I Introduction to Earth System Science; general characteristics and origin of the Universe, solar System and the plants; Meteorites and Asteroids; the Earth-origin, size, shape, mass, density, orbital parameters; Age of the Earth; Geological Time Scale. Unit II Formation of Earth’s core, mantle, crust, hydrosphere, atmosphere and biosphere; Heat budget of the earth, interior of the earthcompositional and mechanical layering; earthquakes and earthquake belts; volcanism-types, products and distribution. Unit III Concept of sea-floor spreading and plate tectonics; origin of oceans, continents, mountain belts, rift valleys; Mid-oceanic ridges, trenches, transforms faults and island arcs. Unit IV Hydrologic Cycle; underground water; Surface water; Atmospherecomposition, mixing circulation; atmosphere-ocean coupling and surface circulation of the ocean; deep sea and global ocean circulation; chemical oceanography. Unit V Weathering, erosion and transportation by wind, rivers, glaciers, oceanic currents; sea level changes; Soils-soil types,processes of formation, soil profile, soil constituents. Unit VI Geological and Geomorphological sub-divisions of the India sub-continent; Hydrogeologic provinces of India; Natural Disasters-Indian context; major mineral and energy resources of the Indian sub-continent. Suggested Readings : 1. Emest W.G. (Editor), Earth Systems Procedures and Issues, Cambridge University Press, 2000. 2. Frank Press and Raymond Siever, Earth, W.H. Freeman and Company New York, 1986. 265 EL 310 (vi) INTELLECTUAL PROPERTY RIGHTS (IPR) (50 Lectures) Total Marks : 50 In this era of liberalization and globalization, the perception about Science and its practices have undergone dramatic change. The importance of protecting the scientific discoveries, with commercial potential or the intellectual property rights is being discussed at all levels — statutory, administrative, and judicial. With India ratifying the WTO agreement, it has become obligatory on its part to follow a minimum acceptable standard for protection and enforcement of intellectual property rights. The purpose of this course is to apprise the students the multifaceted dimensions of this issue. Unit I Introduction to Intellectual Property Historical Perspective, Different Types of IP, Importance of protecting IP. Unit II Copyrights Introduction, How to obtain, Differences from Patents. Unit III Trade Marks Introduction, How to obtain, Different types of marks — Collective marks, certification marks, service marks, Trade names, etc. Differences from Designs. Unit IV Patents Historical Perspective, Basic and associated right, WIPO, PCT system, Traditional Knowledge, Patents and Healthcare — balancing promoting innovation with public health, Software patents and their importance for India. Unit V Geographical Indications Definition, rules for registration, prevention of illegal exploitation, importance to India. Unit VI Industrial Designs Definition, How to obtain, features, International design registration. 266 Unit VII Layout design of integrated circuits Circuit Boards, Integrated Chips, Importance for electronic industry. Unit VIII Trade Secrets Introduction and Historical Perspectives, Scope of Protection, Risks involved and Legal aspects of Trade Secret Protection. Unit IX Different International agreements (a) World Trade Organization (WTO) : (i) General Agreement on Tariffs & Trade (GATT), Trade Related Intellectual Property Rights (TRIPS) agreement (ii) General Agreement on Trade related Services (GATS) (iii) Madrid Protocol (iv) Berne Convention (v) Budapest Treaty (b) Paris Convention Unit X WIPO and TRIPS, IPR and Plant Breeders Rights, IPR and Biodiversity Unit XI IP Infringement issue and enforcement — Role of Judiciary, Role of law enforcement agencies — Police, Customs etc. Economic Value of Intellectual Property — Intangible assets and their valuation, Intellectual Property in the Indian Context— Various laws in India Licensing and technology transfer. Suggested Readings 1. Acharya, N.K. Textbook on intellectual property rights Asia Law House, (2001). 2. Guru, Manjula and Rao, M.B. Understanding Trips : Managing Knowledge in Developing Countries Sage Publications, (2003). 3. Ganguli, P. Intellectual Property Rights : Unleashing the Knowledge Economy, Tata McGraw-Hill (2001). 4. Miller, Arthur Raphael : Davis, Micheal H.; Intellectual Property : Patents, Trademarks and Copyright in a Nutshell; West Group Publishers (2000). 5. Watal, Jayashree, Intellectual property rights in the WTO and developing countries, Oxford University Press, Oxford. 267 EL 310 (vii) COMPUTATIONAL AND DISCRETE MATHEMATICS (50 Lectures) Total Marks : 50 The course is an introduction to Mathematics of Discrete Structure. The advent of modern digital computer has increased the need for understanding of discrete Mathematics. The tools and techniques in the system are going to enable students to appreciate the power and beauty of Mathematics in designing problems-solving strategies in everyday life. Unit I Numerical Solution of ODE Taylor series method, Euler method, Modified Euler method, error in approximation. Unit II Boolean Algebra Formal definition of Boolean algebra and examples, Boolean expressions, Boolean functions, identities in a Boolean algebra, duality, sum-of-product expansion, product-of-sum expansion. Logical Gates, combinational circuits : minimization of circuits using Karnaugh Map (up to 4 variables only), do not care conditions. Unit III Graph Theory Types of graphs : Simple graph, Directed graph, Multi graph, and Pseudo graph. Graph modeling, terminology and basics. Special Graphs : Complete Graph, Cycles, n-dimensional cubes, Bipartite Graph, Complete Bipartite Graph. Subgraph and basic algebraic operations on graphs, connectivity, path, cycles, tree to be introduced as a connected graph with no cycles, introduction to shortest path (least number of edges) problem, solution of shortest path problem for simple graphs using complete enumeration. Euler and Hamiltonian graphs (for undirected graphs only) : Koenigsburg Bridge Problem, statements and interpretations of (i) necessary and sufficient conditions for Euler cycles and paths (ii) suficient condition for Hamiltonian cycles, finding Euler cycles and Hamiltonian cycles in a given graph. 268 Tree traversal, spanning trees, weighted graphs, minimal spanning tree using Kruskal’s algorithm, Prim’s algorithm, Huffman codes. Unit IV Introduction to Algorithms Pseudo code for simple algorithms such as god, lcm, sorting of numbers in ascending/descending order, sum of natural numbers, factorial of a positive integer. Analysis of algorithms, asymptotic upper bounds such as O-estimate (big Oh). Suggested Readings 1. K.H. Rosen, Discrete mathematis and its applications, McGraw-Hill International Editions, 1999. 2. R. Johnsonbaugh and M. Schaefer, Algorithm, Person Education, 2004. 3. C.F. Gerald and P.O. Wheatley, Applied Numerical Analysis, Pearson Education Ind. 2004. 269 FL 310 (viii) MATHEMATICAL METHODS IN LIFE SCIENCES (50 Lectures) Total Marks : 50 This Course is designed to develop in the under-graduate Life Sciences students an awareness of and familiarity with some mathematical techniques and methods which have been applied to Life Sciences. Unit I Mathematical Biology Exponential growth or decay, determination of growth or decay rates. Inhomogeneous, ordinary differential equations of first order arising from growth of a microbial colony, growth in a chemostat. System of ordinary differential equations in Predator — Prey system. Mutation and reversion in bacterial growth. Unit II Statistical methods in Biology Testing differences between samples. How to present a statistical test, t-test for independent samples and matched samples, Z-test for independent samples and matched samples. Mann-Whitney U-test, Wilcoxon signed rank test, chi-square test, testing significance of a correlation coefficient and rank correlation coefficient, Chi-square test of association Confidence limits. Analysis of variance (ANOVA), F-test, Evaluation the multiple regression equation. ANOVA table for multiple regression. Goodness of fit of binomial, Poisson and normal distributions. Use of standard software’s (spreadsheets) for simple statistical analysis. Unit III Discrete Models Modeling molecular evolution : Matrix models of base substitutions for DNA sequences, the Jukes — Cantor model, the Kimura models, Phylogenetic distances. Networks in Biological Sciences : Dynamics of small world networks, scale-free networks, complex networks, cellular automata. 270 Suggested Readings 1. S.I. Rubinov, Introduction to Mathematical Biology, John Wiley and Sons, 1975. 2. A. Edmondson and D. Druce, Advanced Biology Statistics, Oxford University Press, 1996. 3. W. Daniel, A Foundation for Analysis in Health Sciences, John Wiley and Sons Inc. 2004. 4. E.S. Allman and J.A. Rhodes, Mathematical Models in Biology, Cambridge University Press, 2004. 5. N.F. Britton, Essential Mathematical Biology, Springer undergraduate Mathematics series, Springer-Verlag. 2003. The Restructured B.Sc. Programme in Physical Sciences, Life Sciences, Applied Physical Sciences and Applied Life Sciences (Effective from July, 2005) University of Delhi CONTENTS Page No. Guidelines 1-15 Syllabi and Readings 17-270 1st Year 17-52 2nd Year 53-161 3rd Year 163-270 Reference http://www.du.ac.in/course/syllabi/bscprog2005.pdf
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