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JNTU 2007-2008 I YEAR B. PHARMACY-PHYSICAL PHARMACY – I
Posted Date: 09 Dec 2007 Resource Type: Articles/Knowledge Sharing Category: Syllabus
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Posted By: Sri Member Level: Gold
Rating:  Points: 1
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JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY
HYDERABAD
I Year B. Pharmacy T P C
3+1* 0 6
(R7102) PHYSICAL PHARMACY – I
UNIT I
Intermolecular forces and states of matter: Binding forces between molecules, the states of matter, the gaseous state, the liquid state, solids and the crystalline state. Phase equilibria and the phase rule.
UNIT II
Thermodynamics: The first law of thermodynamics. Thermochemistry. The second law of thermodynamics. The third law of thermodynamics, Free energy functions and applications.
UNIT III
Physical properties of Drug Molecules: Dielectric constant induced polarization, dipole moment, refractive index and molar refraction, optical rotatory dispersion.
UNIT IV
Solutions of Non electrolytes: Concentration expressions, ideal and real solutions, colligative properties, molecular weight determinations.
UNIT V
Solutions of Electrolytes: Properties of solutions of electrolytes. The Arrhenius theory of electrolyte dissociation. The modern theory of strong electrolytes and other coefficients for expressing colligative properties.
UNIT VI
Ionic equilibria: Modern theories of acids, bases and salts, Sorensen's pH scale, specific concentration as a function of pH, calculation of pH, graphical solution to pH problems, acidity constants.
UNIT VII
Buffers and buffered isotonic systems: The buffer equation, buffer capacity, buffers in pharmaceutical and biological systems, buffered isotonic solutions, methods of adjusting tonicity and pH (relevant numerical problems).
UNIT VIII
Electromotive force and oxidation Reduction systems: Electrochemical cells. Electrometric determination of pH and redox.
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