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JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY
HYDERABAD
I Year B. Pharmacy T P C
4+1* 0 8
(R7103) PHARMACEUTICAL INORGANIC CHEMISTRY
UNIT- I
1. Classification of Inorganic Pharmaceuticals based on their applications and therapeutic uses.
2. Sources of impurities, quality control and test for purity
3. Qualitative tests for anion and cations
4. Limit tests for Arsenic, heavy metals, lead, iron, chloride and sulphate and Pharmacopoeial standards.
Notes: Definition, Preparation, Assay principle, Limits tests and Uses for the following classes of compoundsfrom Unit II to Unit VII
UNIT - II
1. Electrolytes: Sodium, potassium and calcium replenishers.
2. Sodium and potassium replenishers: Sodium chloride, compound sodium chloride solution (Ringer solution), potassium chloride, ORS.
3. Calcium replenishers: Calcium chloride, calcium gluconate, dibasic calcium phosphate.
4. Acid base regulators: Sodium bicarbonate, sodium lactate, sodium citrate/potassium citrate, sodium acetate, and ammonium chloride
5. Dialysis fluids: Haemodialysis fluids, intraperitoneal dialysis fluids and gastro-intestinal agents.
UNIT III
1. Acidifiers and Antacids: IP monographs: Dilute hydrochloric acid, sodium acid phosphate, sodium bicarbonate, sodium citrate, potassium citrate, aluminium hydroxide gel, dried aluminium hydroxide gel, magnesium oxide (Magnesia), magnesium hydroxide mixture, magnesium carbonate, magnesium trisilicate, calcium carbonate.
2. Adsorbents and related drugs: Light kaolin, heavy kaolin, and activated charcoal.
3. Laxatives: Magnesium sulphate, sodium phosphate.
UNIT -IV
1) Mineral Nutrients/Supplements
(a) Haematinics – Ferrous sulphate, ferrous fumarate, ferrous gluconate, ferric ammonium citrate, iron and dextrose injection.
(b) Halogens: Iodine, Iodides and fluorides.
2) Pharmaceutical aids:
(a) Excipients: Dicalcium phosphate, tricalcium phosphate, magnesium stearate, talc and calcium carbonate (Precipitated chalk).
(b) Suspending agents: Bentonite, colloidal silica, aluminium stearate.
(c) Colorants: Titanium oxide, Ferric oxide
UNIT- V
(a) Expectorants: Ammonium chloride, potassium iodide.
(b) Emetics: Potassium antimony tartarate, copper sulphate, zinc sulphate.
(c) Antidotes: Sodium thiosulphate, sodium nitrite.
UNIT -VI
Topical agents:
1) Astringents: Zinc sulphate, zinc oxide, calcium hydroxide, copper sulphate, Bismuth sub carbonate.
2) Topical protectants: Zinc oxide, calamine, zinc stearate, talc, titanium-dioxide, heavy kaolin and light kaolin (only uses).
3) Silicone polymers: Activated dimethicone.
4) Anti-Infectives: Hydrogen peroxide solution, potassium permanganate, silver nitrate (silver protein), iodine, (solutions of iodine, povidone iodine), boric acid, zinc undecylenate, mercury compounds (yellow mercuric chloride)
UNIT- VII
Dental products:
1) Fluorides: Sodium fluoride, sodium monofluorophosphate and stannous fluoride.
2) Oral antiseptics and Astringents: Hydrogen peroxide, sodium peroxide (bp), magnesium peroxide, zinc peroxide and mouth washes.
3) Dentifrices: Calcium carbonate, dibasic calcium phosphate, calcium phosphate, sodium metaphosphate and strontium chloride.
4) Cements & fillers : Zinc oxide (only uses).
UNIT-VIII
Miscellaneous Medicinal Agents
a) Antineoplastics : Cisplatin
b) Antidepressants : Lithium carbonate
c) Diagnostic agents : Barium sulphate
d) Surgical Aids : Plaster of Paris
e) Antirheumatic agents : Sodium aurothiomalate
f) Internal parasiticid : Sodium antimony gluconate
g) Anti thyroid agents : Potassium perchlorate
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