Fever with joint pain
This article explains about fever with joint pain. Read to know more about fever with joint pain and in autoimmune diseases. Read to know the drugs useful in joint pain.
Fever is the common manifestation of many diseases, and so is the joint pain. When these two symptoms occur together many diseases can be short listed.
There are two terms used to refer joint pain – one is arthralgia, which means joint pain and the other term is arthritis which means inflammation of the joint associated with arthralgia.
Causes of fever with joint pain
When a patient presents with fever and arthritis or arthralgia, the first and foremost important cause comes in clinical practice is of infective origin. Other important causes include autoimmune diseases. There are some drugs which lead to joint pain as there side effects. The details of the causes are described below.
Infections causing fever with joint pain
Infective causes of fever with joint pain include viral infection, bacterial infection and fungal infection. In our clinical practice viral arthritis is probably the commonest form of infective arthritis followed by bacterial or septic arthritis. About 50% of women having rubella infection also called German measles have arthritis with joint pain. The pain is usually in the small joints.
Arthropods born viral infections like Japanese encephalitis, yellow fever, West Nile fever causes fever with joint pain. One of the recent observation is the Chickungunya infection which has been epidemic recently. The joints involved in arthropod born viral infection are usually the larger joints like elbow, hip, knee joints.
Other causes of viral arthritis include mumps, infectious mononucleosis also called glandular fever, Parvo virus 19, Hepatitis B and HIV infection.
Bacterial causes of arthritis are staphylococcus, streptococcus, gram negative bacilli Neisseria gonorrhoea causing sexually transmitted disease called gonorrhoea, Lyme disease. Tuberculosis of the joints is one of the important causes of chronic febrile arthritis in low socioeconomic populations.
Some fungal infections are also a cause for fever with joint pain. These fungi include Candida, Cryptococci etc.
Fever with joint pain in autoimmune diseases
Fever with joint pain is also a manifestation of systemic autoimmune diseases. In India post streptococcal rheumatic fever is one of the leading causes of fever with arthritis. Autoimmune disease like systemic lupus erythematosus (SLE) may also manifest with fever with joint pain. Other causes in this group are rheumatoid arthritis patients may be RA factor positive or negative, Still,s disease, inflammatory bowel disease which include Ulcerative colitis and Crohn’s disease, reactive arthritis which may be associated with urethritis and conjunctivitis and called Reiter’s disease and other vasculitidis.
Acute attack of gout may have fever with joint pain. Even infective endocarditis may manifest as fever with joint pain along with other cardiac symptoms.
Drugs causing fever with joint pain
Some drugs also cause joint pain and if these drugs are administered during an episode of fever. These drugs include quinolones an antibiotic usually used in Typhoid fever and other Gram positive infections. Cefadroxil and cefixime the third generation cephalosporin, clindamycin a macrolide clopidogrel used as an antiplatelet agent in prevention of myocardial infarction and lamuvudin an anti retroviral drug.
Thus a patient with fever and joint pain can be dealt accordingly as per the cause. It is necessary to diagnose the proper cause to ensure proper treatment. For diagnosis and treatment of patient kindly see
Diagnosis and treatment of patient with fever and joint pain.
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M. K. Singh
M. K. Singh
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