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JNTU 2007-08 II Year I Sem B.Pharmacy - PHYSICAL PHARMACY - II


Posted Date: 28 Dec 2007    Resource Type: Articles/Knowledge Sharing    Category: Syllabus

Posted By: India       Member Level: Diamond
Rating:     Points: 1



JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY
HYDERABAD
II Year B. Pharmacy I-Semester T P C
4+1* 0 4
(R7204) PHYSICAL PHARMACY - II

UNIT-I
Solubility and Distribution Phenomena: Solvent-solute interaction, solubility of gases in liquids, liquids in liquids, solids in liquids, distribution of solutes in immiscible solvents.
Introduction to phenomena of diffusion: Ficks first law and second law.

UNIT-II
Complexation: Metal complexes, organic molecular complexes in inclusion complex, and methods of analysis, complexation and drug action.

UNIT-III
Kinetics: Rates and orders of the reaction. Influence of temperature and other factors on reaction rates. Decomposition and stabilization of medicinal agents, kinetics in the solid state and accelerated stability analysis (relevant numerical problems).

UNIT-IV
Interfacial Phenomena: Liquid interfaces, measurement of surface and interfacial tensions, adsorption at liquid interfaces. Surface-active agents and systems of hydrophilic lipophillic classification. Adsorption at solid interfaces. Electrical properties of interfaces.

UNIT-V
Micromeritics: Particle size and size distribution, methods for determining surface area, methods for determining practicle size, pore size, particle shape and surface area, derived properties of powders.

UNIT-VI
Rheology: Newtonian system, non-Newtonian system, thixotropy, measurement and applications in formulations. Determination of viscosity and its applications.

UNIT - VII
Colloids: Introduction, types of colloidal systems, solubilization, Stability of colloids, optical properties, kinetic properties, electrical properties and Donnan Membran equilibraium.

UNIT-VIII
Coarse Dispersions: Suspensions, emulsions: suspensions, interfacial properties of suspended particles. Settling in suspensions. Formulation of suspensions: emulsions- theories of emulsification, physical stability of emulsions, preservation of emulsions, rheological properties of emulsions and suspensions.




Responses

Author: India    28 Dec 2007Member Level: Diamond   Points : 5
TEXT BOOKS

1. Patrick J. Sinko, Martin's Physical Pharmacy and Pharmaceutical Sciences 5th Edition.
2. CVS Subhramanyam, Physical Pharmacy, Vallabh prakashan.
3. L. Lachman, H. Lieberman The Theory And Practice Of Industrial Pharmacy J. L Kaniz Lee & Febiger Philadelphia, USA

REFERENCE

1. Lippincott Williams and Wilkins, Remington Pharmaceutical Sciences
2. M.E. Aulton, Pharmaceutics – The science of dosage form design, 2nd edition
3. Derle D.V., Essentials of Physical Pharmacy.




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