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JNTU 2007-08 III Year I Sem B.Pharmacy - PHARMACEUTICAL BIOCHEMISTRY
Posted Date: 29 Dec 2007 Resource Type: Articles/Knowledge Sharing Category: Syllabus
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Posted By: India Member Level: Diamond
Rating:  Points: 1
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JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY
HYDERABAD
III Year B. Pharmacy I-Semester T P C
4+1* 0 4
(R7401) PHARMACEUTICAL BIOCHEMISTRY
UNIT - I
Bio chemical organization of the cell, molecular constitutents of membrane, active & passive transport process, sodium and potassium pumps, osmoregulation and heamostatis.
UNIT – II
Bio-energetics & Redox Reactions: The concept of free energy, laws of thermodynamics.Determination of change in free energy from equilibrium constant & reduction potential. Production of ATP and its biological significance.
Redox reactions, redox potential, the respiratory chain & its role in energy capture & its control. Oxidative phosphorylation & its energetics & E.T.S mechanism of actions.
UNIT – III
Enzymes & Co-Enzymes: Classification, Structure, mechanism of action, properties, factors affecting enzymes action. Activators & de activators of enzymes, enzyme kinetics & enzyme inhibitions, repressions with reference to drug action.
UNIT - IV
Introduction to Bio-Molecules: Structure, classification, cell and biological functions of carbohydrates, proteins, lipids, nucleic acids (DNA & RNA) vitamins & minerals.
UNIT - V
Metabolism of Carbohydrates: Glycolysis, glycogenolysis, gluconeogenesis, Kreb’s cycle, HMP & uronic acid pathways, anaerobic respiration in muscle.
UNIT – VI
Metabolism of Proteins: Amino acid structure & classifications, de amination, Trans-amination, de-carboxylation, Urea cycle, Metabolism & examples:
Valine, cystine, cystein, tryptophan, tyrocine, methionine.
UNIT – VII
Metabolism of Lipids:
Oxidations : Alpha, Beta, Gama & Omega oxidations of fatty acids, bio-synthesis of fatty acids, cholesterol, ketogenesis.
UNIT – VIII
Introduction to xenobiotic metabolism, detoxification, conjugation, prostaglandins & related products (Ecosanoids).
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Responses
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| Author: India 29 Dec 2007 | Member Level: Diamond Points : 5 | TEXT BOOKS
1. Harper, Biochemistry
2. A.L.Lehninger, Principles of Biochemistry.
3. J.L.Jain, Fundamentals of Biochemistry
4. Satyanarayana, Text Book of Biochemistry
5. Rama Rao, Text Book of Bio Chemistry.
6. Conn, Outlines of biochemistry
REFERENCES
1. L.Stryer, Text Book of Bio Chemistry.
2. E.E Conn & P.K. Stumpf, Outlines of Biochemistry by, Publ, John Wiley & sons, New York.
3. B.Harrow and A. Mazur, Text Book of Biochemistry, WB Saunders Co., Philadelphia.
4. Boyer Rodney, Modern experimental Bio Chemistry.
5. West, Edward Text Book of Biochemistry.
6. Conn, Outlines of Biochemistry.
7. Plummer, Practical Bio Chemistry.
8. Denniston, Topping & Caret; General, Organic, and Biochemistry, McGraw-Hill
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