Interleukins are the group of cytokines. classified as follows with Functions:
IL-1 : Secreted by Macrophages, induced acute phase reaction.
IL-2 : Secreted by T-Cells in an autocrine fashion, stimulate growth and differentiation of T-Cell responce, used in cancer treatment.
IL-3 : Secreted by T-Cells, stimulates Bone marrow stem cells.
IL-4 : Important roll in Allergic Responces.
IL-5 : Play important roll in differentiation of B-Cells, Eosinophil production & IgA production.
IL-6 : Secreted by Macrophages, Induces acute phase reaction.
IL-7 : Involved in B, T, & Nk cell survival.
IL-8 : Neutrophil Chemotaxis.
IL-9 : Stimulates Mast cells.
IL-10: Inhibits Th-1 Cytokine production.
IL-11: Acute phase protein production.
IL-12: Nk-cell stimulation & Th-1 cells induction.
IL-13: Stimulates growth and differentiation of B-cells.
IL-14: Unknown.
IL-15: Induces production of natural killer cells.
IL-16: Unknown.
IL-17: Induces production of inflamatory cytokines.
IL-18: Induces production of interferon gamma.
IL-19: Unknown.
IL-20: Unknown.
IL-21: Unknown.
IL-22: Unknown.
IL-23: Reduces CD8T-Cell infiltration.
IL-24: Unknown.
IL-25: Unknown.
IL-26: Unknown.
IL-27: Unknown.
IL-28: Unknown.
IL-29: Unknown.
IL-30: Unknown.
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