Meaning:"little" is negetive in nature,it has negetive meaning,idea or sense. It is generally used to mean "NONE" or "NO".
Meaning :"A little" is positive in nature,it has positive meaning,idea or sense.It is generally used to mean "SOME" or "SMALL AMOUNT OF".
1)He is fool and has little commonsense.
2)She talked little about his previous job.
3)There is little hope of her recovery.
4)Karen has little hope of her mother's recovery.
5)Pooja showed little concern for her father.
1)Please give me a little water.
2)I will see you in a little while.
3)She has a little chance to win.
4)A little care could have prevented the accident.
5)A little courage by us would have saved the child.