Blaze a trail (in something) to create and develop a new area of study or development.(Literal in reference to creating and marking a trail.
In other words to do something that no-one has done before, especially something which will be important for other people.
To lead the way.
In the area of conservation, Wright and Walters blazed a trail in the use of technology to preserve topsoil.
Professor Williams blazed a trail in the study of physics.
The scout blazed a trail through the forest.
The hospital has blazed a trail in developing new techniques for treating infertility.