Rheumatoid arthritis is a chronic inflammatory joint disease with a multisystem involvement.
female are affected 3 times more often than male.
YES, there is absolute cure for rheumatoid arthritis .
MANAGEMENT OF RHEUMATOID ARTHRITIS.
rest and splinting of joint should be instituted in acute stage of disease.
active and passive physiotherapy help in mobilizations and prevention of contractures.
1)Analgesic like NSAID, aspirin, they acts by suppression of inflammation.
2)Disease modifying antirheumatic drug(DMARDS)
DMARDS reduce inflammation and prevent damage to joints ,bone,and ligament.these agent take 3-4 month before their full effect.
3)BIOLOGICAL RESPONSE MODIFIERS
newer agent that block specific immune factor leading to RA.
anti-TNF -alpha antibodies include infliximab and etanercept.
interleukin -1 receptor blocker include anakinra.
Rituximab an anti -CD20 antibody which block CD20 present on B cells.
this is third line t/t drug.
used in acute stage of disease.